SELL and PODXL2

Number of citations of the paper that reports this interaction (PubMedID 12889478)
0

Data Source:
HPRD (in vivo)

		SELL	PODXL2
Description		selectin L	podocalyxin like 2
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane External Side Of Plasma Membrane Membrane Secretory Granule Membrane	Golgi Lumen Plasma Membrane Membrane
	Molecular Function	Protease Binding Calcium Ion Binding Protein Binding Heparin Binding Carbohydrate Binding Sialic Acid Binding Glycosphingolipid Binding Metal Ion Binding Oligosaccharide Binding	Protein Binding Glycosaminoglycan Binding
	Biological Process	Cell Adhesion Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Leukocyte Cell-cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Response To Cytokine Leukocyte Migration Leukocyte Tethering Or Rolling Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules	Cell Adhesion Leukocyte Tethering Or Rolling
Pathways		Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Cell surface interactions at the vascular wall Neutrophil degranulation	Cytosolic sulfonation of small molecules
Drugs
Diseases
GWAS		Acne (severe) ( 24399259) Amyotrophic lateral sclerosis ( 19451621) Basophil percentage of white cells ( 32888494) Blood protein levels ( 30072576) Eosinophil percentage of white cells ( 32888494) Inflammatory bowel disease ( 26192919) L-selectin levels ( 25576479) Monocyte count ( 32888494)	Refractive error ( 32231278)
Interacting Genes		16 interacting genes: CD4 CFH EMCN EZR GRB2 MSN MUC7 PODXL PODXL2 PRKCA PRKCQ PRKG1 SELE SELPLG SLC30A2 VCAN	1 interacting genes: SELL
Entrez ID		6402	50512
HPRD ID		07034	15154
Ensembl ID		ENSG00000188404	ENSG00000114631
Uniprot IDs		P14151	Q9NZ53
PDB IDs		2LGF 3CFW 5VC1
Enriched GO Terms of Interacting Partners?		Leukocyte Cell-cell Adhesion Cell Adhesion Regulation Of Cell-cell Adhesion Uropod Plasma Membrane Leukocyte Tethering Or Rolling Leukocyte Adhesion To Vascular Endothelial Cell Microvillus Membrane Regulation Of Platelet Aggregation Positive Regulation Of Cell Adhesion Regulation Of Cell Adhesion Cell Migration Membrane To Membrane Docking Positive Regulation Of Cell-cell Adhesion Regulation Of Platelet Activation Cell Motility Regulation Of Interleukin-2 Production Positive Regulation Of Early Endosome To Late Endosome Transport Microvillus Regulation Of Immune System Process Positive Regulation Of Protein Localization To Early Endosome Filopodium Positive Regulation Of Protein Localization To Endosome Cell-cell Adhesion Positive Regulation Of Leukocyte Cell-cell Adhesion Immune System Process Golgi Lumen Establishment Of Epithelial Cell Apical/basal Polarity Diacylglycerol-dependent Serine/threonine Kinase Activity Leukocyte Activation Regulation Of Early Endosome To Late Endosome Transport T Cell Activation Establishment Of Apical/basal Cell Polarity Positive Regulation Of Immune System Process Regulation Of Cell Activation Glycosaminoglycan Binding Epithelial Cell Development Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Polarized Epithelial Cell Differentiation Cell Activation Cortical Cytoskeleton Gland Morphogenesis Establishment Of Epithelial Cell Polarity Regulation Of Leukocyte Cell-cell Adhesion Signaling Receptor Binding Actin Filament-based Process Plasma Membrane Raft Positive Regulation Of Interleukin-2 Production Establishment Of Endothelial Barrier	Cell Migration Sialic Acid Binding Glycosphingolipid Binding Leukocyte Tethering Or Rolling Oligosaccharide Binding Leukocyte Adhesion To Vascular Endothelial Cell Semaphorin Receptor Activity Synaptic Target Recognition Lamellipodium Membrane Semaphorin Receptor Complex Dichotomous Subdivision Of Terminal Units Involved In Salivary Gland Branching Plasma Membrane Bounded Cell Projection Coronary Vasculature Development Cell Motility Aorta Development Branching Involved In Blood Vessel Morphogenesis Heterophilic Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Artery Development Cardiac Septum Development Neuron Recognition Semaphorin-plexin Signaling Pathway Leukocyte Cell-cell Adhesion Outflow Tract Morphogenesis Positive Regulation Of Axonogenesis Cell Body Endothelial Cell Migration Secretory Granule Membrane Synapse Assembly
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