TRAPPC2 and MBD3L1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		TRAPPC2	MBD3L1
Description		trafficking protein particle complex subunit 2	methyl-CpG binding domain protein 3 like 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm TRAPPII Protein Complex TRAPPIII Protein Complex	Nucleus
	Molecular Function	Protein Binding Transmembrane Transporter Binding	Protein Binding Methyl-CpG Binding
	Biological Process	Skeletal System Development Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport COPII Vesicle Coating Vesicle Tethering	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation-dependent Constitutive Heterochromatin Formation
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs
Drugs
Diseases		Spondyloepiphyseal dysplasia tarda
GWAS
Interacting Genes		34 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 KCTD1 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 SNCA TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBTB38 ZNF438 ZNF655 ZRANB1	44 interacting genes: AIRIM ANKS1A BOLA2 BOLA2B C1orf74 CLCNKA CLIC3 CTNNA3 DTX2 EFHC1 EXOC8 FAM124B FHL2 FNDC3B FRS3 GPSM3 GTPBP3 IL16 KCTD9 KIFC3 LMO1 LMO3 MAD2L2 MBD2 MBD3 MLH1 MPPED2 NDUFAF3 NEK6 NXF1 SH2D4A SNAPC5 SNRPB STX11 SUOX TRAPPC2 TRAPPC2B TSGA10 TSGA10IP TSSK3 UBL5 USP20 ZNF76 ZNF77
Entrez ID		6399	85509
HPRD ID		02189	12138
Ensembl ID		ENSG00000196459	ENSG00000170948
Uniprot IDs		P0DI81 P0DI82 Q6IBE5	Q8WWY6
PDB IDs
Enriched GO Terms of Interacting Partners?		TRAPP Complex Vesicle Tethering TRAPPII Protein Complex Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport TRAPPIII Protein Complex Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity COPII Vesicle Coating Golgi Vesicle Transport Protein Binding Cis-Golgi Network Membrane Vesicle-mediated Transport Vesicle Organization Intracellular Transport Establishment Of Localization In Cell	Protein Binding Vesicle Tethering Response To Bisphenol A
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