MBD3L1 and NDUFAF3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MBD3L1	NDUFAF3
Description		methyl-CpG binding domain protein 3 like 1	NADH:ubiquinone oxidoreductase complex assembly factor 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Mitochondrion Mitochondrial Inner Membrane Membrane
	Molecular Function	Protein Binding Methyl-CpG Binding	Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation-dependent Constitutive Heterochromatin Formation	Mitochondrial Respiratory Chain Complex I Assembly
Pathways			Complex I biogenesis
Drugs
Diseases			Mitochondrial respiratory chain deficiencies (MRCD), including: Mitochondrial complex I deficiency (MT-C1D); Complex II deficiency (MT-C2D); Complex III deficiency (MT-C3D); Complex IV deficiency (MT-C4D); Complex V deficiency (MT-ATPSD); Leigh syndrome (LS); Kearns-Sayre Syndrome (KSS); LCHD deficiency (LCHD); Leber Hereditary Optic Neuropathy (LHON); Myoclonic Epilepsy and Ragged-Red Fiber Disease (MERRF); NARP; MELAS; ACAD9 deficiency; HADH deficiency; HIBCH deficiency; GRACILE syndrome
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Inflammatory bowel disease ( 28067908) Mood instability ( 31168069) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		44 interacting genes: AIRIM ANKS1A BOLA2 BOLA2B C1orf74 CLCNKA CLIC3 CTNNA3 DTX2 EFHC1 EXOC8 FAM124B FHL2 FNDC3B FRS3 GPSM3 GTPBP3 IL16 KCTD9 KIFC3 LMO1 LMO3 MAD2L2 MBD2 MBD3 MLH1 MPPED2 NDUFAF3 NEK6 NXF1 SH2D4A SNAPC5 SNRPB STX11 SUOX TRAPPC2 TRAPPC2B TSGA10 TSGA10IP TSSK3 UBL5 USP20 ZNF76 ZNF77	16 interacting genes: AGTRAP CABP2 CYSRT1 GEM GOLGA6L9 INCA1 KRT27 KRTAP10-3 LSM1 MBD3L1 POU2AF1 RBCK1 REL RNF146 SNRPA UHMK1
Entrez ID		85509	25915
HPRD ID		12138	16809
Ensembl ID		ENSG00000170948	ENSG00000178057
Uniprot IDs		Q8WWY6	A4FU71 Q9BU61
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Vesicle Tethering Response To Bisphenol A
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