MBD3L1 and GPSM3

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MBD3L1	GPSM3
Description		methyl-CpG binding domain protein 3 like 1	G protein signaling modulator 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Cytoplasm Plasma Membrane
	Molecular Function	Protein Binding Methyl-CpG Binding	Protein Binding GTPase Regulator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation-dependent Constitutive Heterochromatin Formation	Positive Regulation Of Leukocyte Chemotaxis Regulation Of Inflammatory Response Positive Regulation Of Inflammatory Response Positive Regulation Of Cytokine Production Involved In Inflammatory Response
Pathways			G alpha (i) signalling events
Drugs
Diseases
GWAS			A body shape index ( 34021172) Asthma ( 31619474) Atopic dermatitis ( 23042114 25574825) Autism spectrum disorder or schizophrenia ( 28540026) Bipolar disorder ( 31043756) Body mass index ( 31453325) Body mass index variance ( 31453325) Estimated glomerular filtration rate ( 31152163) Hip circumference ( 31453325) Hip circumference variance ( 31453325) Inflammatory bowel disease ( 28067908) Obesity-related traits ( 23251661) Prostate cancer ( 23535732) Sarcoidosis (non-Lofgren's syndrome without extrapulmonary manifestations) ( 26651848) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)
Interacting Genes		44 interacting genes: AIRIM ANKS1A BOLA2 BOLA2B C1orf74 CLCNKA CLIC3 CTNNA3 DTX2 EFHC1 EXOC8 FAM124B FHL2 FNDC3B FRS3 GPSM3 GTPBP3 IL16 KCTD9 KIFC3 LMO1 LMO3 MAD2L2 MBD2 MBD3 MLH1 MPPED2 NDUFAF3 NEK6 NXF1 SH2D4A SNAPC5 SNRPB STX11 SUOX TRAPPC2 TRAPPC2B TSGA10 TSGA10IP TSSK3 UBL5 USP20 ZNF76 ZNF77	44 interacting genes: ACMSD ANKRD33 ASB15 BATF2 BMF C9orf57 CHRDL2 COA7 CTAG1A CTAG1B FAM86C1P FGFR3 GATAD2B GNAI1 GNAI2 GNAI3 HELT HIGD2B HRAS HSF2BP IQCE IVD KCNJ5-AS1 KRTAP11-1 KRTAP13-3 KRTAP19-4 MAPK7 MBD3L1 MEOX2 NR0B2 P4HA3 PRR5 RIPK4 RSPO4 SPAG8 SPMIP5 SPRY3 STXBP5L TADA2A TEX11 UFSP1 USHBP1 ZNF20 ZNF581
Entrez ID		85509	63940
HPRD ID		12138	13605
Ensembl ID		ENSG00000170948	ENSG00000213654
Uniprot IDs		Q8WWY6	A0A024RCP6 Q9Y4H4
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Vesicle Tethering Response To Bisphenol A	Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding Heterotrimeric G-protein Complex
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