MBD3L1 and ZNF77

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MBD3L1	ZNF77
Description		methyl-CpG binding domain protein 3 like 1	zinc finger protein 77
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	Protein Binding Methyl-CpG Binding	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA Methylation-dependent Constitutive Heterochromatin Formation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways			Generic Transcription Pathway
Drugs
Diseases
GWAS			Chronic kidney disease ( 30226566) Coronary artery disease ( 30402224) Daytime sleep phenotypes ( 27126917) Ischemic stroke ( 29930801) Myocardial infarction ( 30226566)
Interacting Genes		44 interacting genes: AIRIM ANKS1A BOLA2 BOLA2B C1orf74 CLCNKA CLIC3 CTNNA3 DTX2 EFHC1 EXOC8 FAM124B FHL2 FNDC3B FRS3 GPSM3 GTPBP3 IL16 KCTD9 KIFC3 LMO1 LMO3 MAD2L2 MBD2 MBD3 MLH1 MPPED2 NDUFAF3 NEK6 NXF1 SH2D4A SNAPC5 SNRPB STX11 SUOX TRAPPC2 TRAPPC2B TSGA10 TSGA10IP TSSK3 UBL5 USP20 ZNF76 ZNF77	7 interacting genes: FTO MBD3L1 METTL27 NICN1 PRDX3 RSPO4 RUSC1
Entrez ID		85509	58492
HPRD ID		12138	08936
Ensembl ID		ENSG00000170948	ENSG00000175691
Uniprot IDs		Q8WWY6	Q15935
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding Vesicle Tethering Response To Bisphenol A	NADH-dependent Peroxiredoxin Activity RNA Repair TRNA Demethylase Activity MRNA N6-methyladenosine Dioxygenase Activity
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