TRAPPC2 and NICN1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid, two hybrid)

		TRAPPC2	NICN1
Description		trafficking protein particle complex subunit 2	nicolin 1, tubulin polyglutamylase complex subunit
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Endoplasmic Reticulum Endoplasmic Reticulum-Golgi Intermediate Compartment Cytosol TRAPP Complex Perinuclear Region Of Cytoplasm TRAPPII Protein Complex TRAPPIII Protein Complex	Nucleus Nucleoplasm Microtubule
	Molecular Function	Protein Binding Transmembrane Transporter Binding	Protein Binding
	Biological Process	Skeletal System Development Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle Coating Vesicle-mediated Transport COPII Vesicle Coating Vesicle Tethering
Pathways		COPII-mediated vesicle transport RAB GEFs exchange GTP for GDP on RABs	Carboxyterminal post-translational modifications of tubulin
Drugs
Diseases		Spondyloepiphyseal dysplasia tarda
GWAS			Brain morphology (min-P) ( 32665545) Brain morphology (MOSTest) ( 32665545) Cognitive function ( 25644384) Cortical surface area (MOSTest) ( 32665545) Crohn's disease ( 28067908) Depressive symptoms (binary sum-score) ( 31530331) Extremely high intelligence ( 29520040) General cognitive ability ( 29844566) Inflammatory bowel disease ( 28067908) Intelligence (MTAG) ( 29326435) Mood instability ( 31168069) Red cell distribution width ( 28957414) Refractive error ( 32231278) Regular attendance at a religious group ( 29970889) Sleep duration (short sleep) ( 30846698) Subcortical volume (min-P) ( 32665545) Subcortical volume (MOSTest) ( 32665545) Ulcerative colitis ( 28067908)
Interacting Genes		34 interacting genes: ABRA CLIC1 CLIC2 DAPK1 EIF3C ENO1 ENO3 EPS15L1 HLA-E INCA1 KCTD1 MBD3L1 MFHAS1 NICN1 NME4 NR5A1 PITX1 PYGM REPS1 SLC25A35 SNAPC5 SNCA TEPSIN TRAPPC3 TRAPPC3L TRAPPC4 TRAPPC6A TRAPPC6B TRAPPC9 UQCC2 ZBTB38 ZNF438 ZNF655 ZRANB1	11 interacting genes: ATP6V0D2 NFKBID P4HA3 POGZ RUSC1 TENT5B TLX3 TRAPPC2 TRAPPC2B TTC9C ZNF77
Entrez ID		6399	84276
HPRD ID		02189	17631
Ensembl ID		ENSG00000196459	ENSG00000145029
Uniprot IDs		P0DI81 P0DI82 Q6IBE5	Q9BSH3
PDB IDs
Enriched GO Terms of Interacting Partners?		TRAPP Complex Vesicle Tethering TRAPPII Protein Complex Vesicle Coating Endoplasmic Reticulum To Golgi Vesicle-mediated Transport TRAPPIII Protein Complex Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity COPII Vesicle Coating Golgi Vesicle Transport Protein Binding Cis-Golgi Network Membrane Vesicle-mediated Transport Vesicle Organization Intracellular Transport Establishment Of Localization In Cell	TRAPPII Protein Complex TRAPPIII Protein Complex TRAPP Complex COPII Vesicle Coating Vesicle Tethering Vesicle Coating Endoplasmic Reticulum-Golgi Intermediate Compartment Plasma Membrane Proton-transporting V-type ATPase Complex
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