CLSPN and USP29

Number of citations of the paper that reports this interaction (PMID 24632611)
2

Data Source:
BioGRID (affinity chromatography technology, enzymatic study)

		CLSPN	USP29
Gene Name		claspin	ubiquitin specific peptidase 29
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm	Cellular_component Nucleus
	Molecular Function	DNA Binding Protein Binding Anaphase-promoting Complex Binding	Cysteine-type Endopeptidase Activity Ubiquitin-specific Protease Activity
	Biological Process	DNA Damage Checkpoint DNA Replication DNA Repair Apoptotic Process Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Peptidyl-serine Phosphorylation G2 DNA Damage Checkpoint Activation Of Protein Kinase Activity Mitotic DNA Replication Checkpoint	Protein Deubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Proteasomal Protein Catabolic Process
Pathways		Apoptotic cleavage of cellular proteins G2/M Checkpoints Activation of ATR in response to replication stress Programmed Cell Death Apoptotic execution phase Cell Cycle Checkpoints
Drugs
Diseases
GWAS
Protein-Protein Interactions		10 interactors: ATR BRCA1 CASP7 CDC7 CHEK1 FZR1 RAD9A USP28 USP29 USP7	1 interactors: CLSPN
Entrez ID		63967	57663
HPRD ID		09257	07163
Ensembl ID		ENSG00000092853	ENSG00000131864
Uniprot IDs		Q9HAW4	Q9HBJ7
PDB IDs
Enriched GO Terms of Interacting Partners?		DNA Repair DNA Damage Checkpoint Cellular Response To DNA Damage Stimulus Cell Cycle Checkpoint DNA Metabolic Process Cellular Response To Stress Cell Cycle Process DNA Replication Regulation Of Cellular Protein Metabolic Process Regulation Of Proteolysis Regulation Of Response To DNA Damage Stimulus Cell Cycle Regulation Of Protein Metabolic Process Cellular Response To Radiation Response To Ionizing Radiation G2 DNA Damage Checkpoint Response To Radiation Regulation Of Histone H3-K9 Acetylation Cellular Response To UV Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Response To DNA Damage Stimulus Proteasomal Protein Catabolic Process Cellular Protein Modification Process Double-strand Break Repair Via Homologous Recombination Recombinational Repair Cellular Response To Light Stimulus Response To Stress Protein Deubiquitination Cellular Macromolecule Catabolic Process Regulation Of Protein Catabolic Process Protein Modification By Small Protein Removal Protein Metabolic Process Regulation Of Cell Cycle Response To UV Replicative Senescence Double-strand Break Repair Regulation Of Cell Cycle Process Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Cellular Protein Metabolic Process Response To Abiotic Stimulus Proteolysis Involved In Cellular Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway Cellular Protein Catabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Proteasomal Protein Catabolic Process Cellular Response To Stimulus Protein Catabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process	Mitotic DNA Replication Checkpoint DNA Replication Checkpoint Negative Regulation Of G2/M Transition Of Mitotic Cell Cycle Negative Regulation Of Cell Cycle G2/M Phase Transition G2 DNA Damage Checkpoint Regulation Of G2/M Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G2/M Phase Transition Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Execution Phase Of Apoptosis Mitotic DNA Integrity Checkpoint Peptidyl-serine Phosphorylation Negative Regulation Of Mitotic Cell Cycle Phase Transition DNA Damage Checkpoint Mitotic Cell Cycle Checkpoint Regulation Of Mitotic Cell Cycle Phase Transition Negative Regulation Of Mitotic Cell Cycle Regulation Of Cell Cycle Phase Transition Cell Cycle Checkpoint Activation Of Protein Kinase Activity DNA Replication
Tagcloud ?		aplp1 attempted bioinformatics candidates carcinogenic carcinogenicity cav1 comet cytoprotective fosl2 functioned h2ax imbalance lethal mica mutagenicity nickel nrf2 pcaf pim2 prame principally qrt redox regarded runx1 slc7a6 synergistic toxicants
Tagcloud (Difference) ?		aplp1 attempted bioinformatics candidates carcinogenic carcinogenicity cav1 comet cytoprotective fosl2 functioned h2ax imbalance lethal mica mutagenicity nickel nrf2 pcaf pim2 prame principally qrt redox regarded runx1 slc7a6 synergistic toxicants
Tagcloud (Intersection) ?