CCL24 and CCL5

Number of citations of the paper that reports this interaction (PubMedID 28381538)
0

Data Source:
BioGRID (pull down, pull down)

		CCL24	CCL5
Description		C-C motif chemokine ligand 24	C-C motif chemokine ligand 5
Image
GO Annotations	Cellular Component	Extracellular Region Extracellular Space	Extracellular Region Extracellular Space Cytoplasm
	Molecular Function	Cytokine Activity Protein Binding Chemokine Activity CCR3 Chemokine Receptor Binding Receptor Ligand Activity CCR Chemokine Receptor Binding	Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Protein Kinase Activity Cytokine Activity Protein Binding Chemokine Activity Phospholipase Activator Activity Receptor Signaling Protein Tyrosine Kinase Activator Activity CCR1 Chemokine Receptor Binding CCR4 Chemokine Receptor Binding CCR5 Chemokine Receptor Binding Chemoattractant Activity Chemokine Receptor Binding Identical Protein Binding Protein Homodimerization Activity Chemokine Receptor Antagonist Activity CCR Chemokine Receptor Binding
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Chemotaxis Inflammatory Response Immune Response Cytoskeleton Organization Signal Transduction Cell-cell Signaling Regulation Of Cell Shape Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Angiogenesis Eosinophil Chemotaxis Positive Regulation Of Inflammatory Response Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Positive Regulation Of Eosinophil Migration	Dendritic Cell Chemotaxis Monocyte Chemotaxis Regulation Of Chronic Inflammatory Response Calcium Ion Transport Intracellular Calcium Ion Homeostasis Exocytosis Chemotaxis Inflammatory Response Immune Response Leukocyte Cell-cell Adhesion G Protein-coupled Receptor Signaling Pathway Cell-cell Signaling Response To Virus Response To Toxic Substance Positive Regulation Of Macrophage Chemotaxis Positive Regulation Of T Cell Chemotaxis Positive Regulation Of Smooth Muscle Cell Migration Positive Regulation Of Cell Migration Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of TOR Signaling Positive Regulation Of Cell-cell Adhesion Mediated By Integrin Response To Cytokine Positive Regulation Of Homotypic Cell-cell Adhesion Response To Tumor Necrosis Factor Chemokine (C-C Motif) Ligand 5 Signaling Pathway Positive Regulation Of T Cell Proliferation Neutrophil Activation Host-mediated Suppression Of Viral Transcription Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Viral Genome Replication Negative Regulation Of Viral Genome Replication Positive Regulation Of Innate Immune Response Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Positive Regulation Of Translational Initiation Eosinophil Chemotaxis Macrophage Chemotaxis Positive Regulation Of Smooth Muscle Cell Proliferation Epithelial Cell Proliferation Positive Regulation Of Epithelial Cell Proliferation Regulation Of Insulin Secretion Regulation Of T Cell Activation Positive Chemotaxis Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Calcium Ion Transport Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemokine-mediated Signaling Pathway Negative Regulation Of Chemokine-mediated Signaling Pathway Negative Regulation Of T Cell Apoptotic Process Positive Regulation Of T Cell Apoptotic Process ERK1 And ERK2 Cascade Cellular Response To Type II Interferon Cellular Response To Interleukin-1 Cellular Response To Tumor Necrosis Factor Positive Regulation Of Monocyte Chemotaxis Cell Surface Receptor Signaling Pathway Via STAT Cellular Response To Virus Positive Regulation Of Neuroinflammatory Response Positive Regulation Of Receptor Signaling Pathway Via STAT Negative Regulation Of Macrophage Apoptotic Process Positive Regulation Of T Cell Migration Positive Regulation Of Natural Killer Cell Chemotaxis
Pathways			Chemokine receptors bind chemokines G alpha (i) signalling events Interleukin-10 signaling
Drugs			Heparin Disaccharide I-S Heparin Disaccharide Iii-S
Diseases
GWAS		CCL24 levels ( 25147954) Eosinophil count ( 27863252 32888494) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252 32888494) Neonatal cytokine/chemokine levels (fetal genetic effect) ( 30134952) Response to cognitive-behavioural therapy in major depressive disorder ( 31123309) Sarcoidosis ( 32826979) Sum eosinophil basophil counts ( 27863252)	Blood protein levels ( 30072576)
Interacting Genes		6 interacting genes: CCL13 CCL21 CCL5 CCR3 CXCL11 XCL1	55 interacting genes: ACKR1 ACKR2 ACKR4 APC BAG4 BCAR3 CCL11 CCL13 CCL16 CCL17 CCL2 CCL20 CCL21 CCL24 CCL25 CCL26 CCL27 CCL28 CCR1 CCR3 CCR4 CCR5 CHEK2 CXCL10 CXCL11 CXCL12 CXCL14 CXCL17 CXCL2 CXCL6 CXCL8 CXCL9 DPP4 EDC4 FZR1 GRB2 IGFBP7 KRAS PALB2 PF4 PHB1 PIGR PPBP PTPN1 RANGAP1 RELA SDC1 SDC4 SLC2A5 TGFB1 TRIP6 VCAN WT1 XCL1 XCL2
Entrez ID		6369	6352
HPRD ID		03931	01751
Ensembl ID		ENSG00000106178	ENSG00000271503
Uniprot IDs		O00175	A0A494C1Q1 D0EI67 P13501
PDB IDs		1EIG 1EIH	1B3A 1EQT 1HRJ 1RTN 1RTO 1U4L 1U4M 1U4P 1U4R 2L9H 2VXW 5CMD 5COY 5DNF 5L2U 5UIW 6AEZ 6C6D 6FGP 6LOG 6STK 7F1R 7O7F
Enriched GO Terms of Interacting Partners?		Chemokine-mediated Signaling Pathway Chemokine Activity Cytokine-mediated Signaling Pathway Cell Chemotaxis CCR Chemokine Receptor Binding Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Chemotaxis Locomotion Leukocyte Chemotaxis Antimicrobial Humoral Response Chemokine Receptor Binding Cytokine Activity Inflammatory Response Granulocyte Chemotaxis Positive Regulation Of T Cell Chemotaxis Leukocyte Migration Regulation Of T Cell Chemotaxis Humoral Immune Response Granulocyte Migration Positive Regulation Of Lymphocyte Chemotaxis Eosinophil Chemotaxis Eosinophil Migration Mononuclear Cell Migration Regulation Of Lymphocyte Chemotaxis Killing Of Cells Of Another Organism Myeloid Leukocyte Migration G Protein-coupled Receptor Signaling Pathway Positive Regulation Of T Cell Migration Cell Migration Positive Regulation Of Lymphocyte Migration Cell Killing Regulation Of T Cell Migration Cell Motility Regulation Of Granulocyte Chemotaxis Positive Regulation Of Natural Killer Cell Chemotaxis Cell Surface Receptor Signaling Pathway Immune Response Cell-cell Signaling Regulation Of Lymphocyte Migration Signaling Cell Communication Defense Response Defense Response To Symbiont Defense Response To Other Organism Positive Regulation Of Leukocyte Chemotaxis Positive Regulation Of Mononuclear Cell Migration Positive Regulation Of Calcium Ion Transport Regulation Of Translational Initiation Eukaryotic Translation Initiation Factor 4F Complex Cellular Response To Cytokine Stimulus	Chemokine Activity Cell Chemotaxis Chemotaxis Locomotion Chemokine-mediated Signaling Pathway Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide Antimicrobial Humoral Response Cell Migration Cytokine Activity Leukocyte Chemotaxis Cell Motility Inflammatory Response Humoral Immune Response Leukocyte Migration Granulocyte Chemotaxis Myeloid Leukocyte Migration Granulocyte Migration Cytokine-mediated Signaling Pathway Immune Response Killing Of Cells Of Another Organism Defense Response Cell Killing Defense Response To Symbiont Defense Response To Other Organism Immune System Process Response To Stress CXCR Chemokine Receptor Binding G Protein-coupled Receptor Signaling Pathway Signal Transduction Response To Other Organism CCR Chemokine Receptor Binding Response To External Biotic Stimulus Extracellular Space Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Regulation Of Cell Migration Eosinophil Chemotaxis Mononuclear Cell Migration Extracellular Region Positive Regulation Of Locomotion Eosinophil Migration Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Leukocyte Migration Neutrophil Chemotaxis Chemokine Receptor Binding C-C Chemokine Binding Neutrophil Migration Positive Regulation Of Leukocyte Migration
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?