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CCL5 and CCL16
Number of citations of the paper that reports this interaction (PubMedID
28381538
)
0
Data Source:
BioGRID
(pull down)
CCL5
CCL16
Description
C-C motif chemokine ligand 5
C-C motif chemokine ligand 16
Image
GO Annotations
Cellular Component
Extracellular Region
Extracellular Space
Cytoplasm
Extracellular Region
Extracellular Space
Molecular Function
Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity
Protein Kinase Activity
Cytokine Activity
Protein Binding
Chemokine Activity
Phospholipase Activator Activity
Receptor Signaling Protein Tyrosine Kinase Activator Activity
CCR1 Chemokine Receptor Binding
CCR4 Chemokine Receptor Binding
CCR5 Chemokine Receptor Binding
Chemoattractant Activity
Chemokine Receptor Binding
Identical Protein Binding
Protein Homodimerization Activity
Chemokine Receptor Antagonist Activity
CCR Chemokine Receptor Binding
Cytokine Activity
Protein Binding
Chemokine Activity
Chemoattractant Activity
CCR Chemokine Receptor Binding
Biological Process
Dendritic Cell Chemotaxis
Monocyte Chemotaxis
Regulation Of Chronic Inflammatory Response
Calcium Ion Transport
Intracellular Calcium Ion Homeostasis
Exocytosis
Chemotaxis
Inflammatory Response
Immune Response
Leukocyte Cell-cell Adhesion
G Protein-coupled Receptor Signaling Pathway
Cell-cell Signaling
Response To Virus
Response To Toxic Substance
Positive Regulation Of Macrophage Chemotaxis
Positive Regulation Of T Cell Chemotaxis
Positive Regulation Of Smooth Muscle Cell Migration
Positive Regulation Of Cell Migration
Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of TOR Signaling
Positive Regulation Of Cell-cell Adhesion Mediated By Integrin
Response To Cytokine
Positive Regulation Of Homotypic Cell-cell Adhesion
Response To Tumor Necrosis Factor
Chemokine (C-C Motif) Ligand 5 Signaling Pathway
Positive Regulation Of T Cell Proliferation
Neutrophil Activation
Host-mediated Suppression Of Viral Transcription
Cellular Response To Fibroblast Growth Factor Stimulus
Positive Regulation Of Viral Genome Replication
Negative Regulation Of Viral Genome Replication
Positive Regulation Of Innate Immune Response
Negative Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of G Protein-coupled Receptor Signaling Pathway
Positive Regulation Of Cell Adhesion
Positive Regulation Of Translational Initiation
Eosinophil Chemotaxis
Macrophage Chemotaxis
Positive Regulation Of Smooth Muscle Cell Proliferation
Epithelial Cell Proliferation
Positive Regulation Of Epithelial Cell Proliferation
Regulation Of Insulin Secretion
Regulation Of T Cell Activation
Positive Chemotaxis
Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction
Positive Regulation Of Calcium Ion Transport
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Negative Regulation Of Chemokine-mediated Signaling Pathway
Negative Regulation Of T Cell Apoptotic Process
Positive Regulation Of T Cell Apoptotic Process
ERK1 And ERK2 Cascade
Cellular Response To Type II Interferon
Cellular Response To Interleukin-1
Cellular Response To Tumor Necrosis Factor
Positive Regulation Of Monocyte Chemotaxis
Cell Surface Receptor Signaling Pathway Via STAT
Cellular Response To Virus
Positive Regulation Of Neuroinflammatory Response
Positive Regulation Of Receptor Signaling Pathway Via STAT
Negative Regulation Of Macrophage Apoptotic Process
Positive Regulation Of T Cell Migration
Positive Regulation Of Natural Killer Cell Chemotaxis
Chemotaxis
Inflammatory Response
Immune Response
Cell Communication
Cell-cell Signaling
Positive Regulation Of Cell Migration
Eosinophil Chemotaxis
Positive Chemotaxis
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Chemokine-mediated Signaling Pathway
Pathways
Chemokine receptors bind chemokines
G alpha (i) signalling events
Interleukin-10 signaling
Chemokine receptors bind chemokines
G alpha (i) signalling events
Drugs
Heparin Disaccharide I-S
Heparin Disaccharide Iii-S
Diseases
GWAS
Blood protein levels (
30072576
)
Initial pursuit acceleration (
29064472
)
Interacting Genes
55 interacting genes:
ACKR1
ACKR2
ACKR4
APC
BAG4
BCAR3
CCL11
CCL13
CCL16
CCL17
CCL2
CCL20
CCL21
CCL24
CCL25
CCL26
CCL27
CCL28
CCR1
CCR3
CCR4
CCR5
CHEK2
CXCL10
CXCL11
CXCL12
CXCL14
CXCL17
CXCL2
CXCL6
CXCL8
CXCL9
DPP4
EDC4
FZR1
GRB2
IGFBP7
KRAS
PALB2
PF4
PHB1
PIGR
PPBP
PTPN1
RANGAP1
RELA
SDC1
SDC4
SLC2A5
TGFB1
TRIP6
VCAN
WT1
XCL1
XCL2
6 interacting genes:
CCL5
CCR1
CCR5
CCR8
HRH4
UBQLN2
Entrez ID
6352
6360
HPRD ID
01751
03233
Ensembl ID
ENSG00000271503
ENSG00000275152
Uniprot IDs
A0A494C1Q1
D0EI67
P13501
O15467
PDB IDs
1B3A
1EQT
1HRJ
1RTN
1RTO
1U4L
1U4M
1U4P
1U4R
2L9H
2VXW
5CMD
5COY
5DNF
5L2U
5UIW
6AEZ
6C6D
6FGP
6LOG
6STK
7F1R
7O7F
5LTL
7SCT
8FK9
Enriched GO Terms of Interacting Partners
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Chemokine Activity
Cell Chemotaxis
Chemotaxis
Locomotion
Chemokine-mediated Signaling Pathway
Antimicrobial Humoral Immune Response Mediated By Antimicrobial Peptide
Antimicrobial Humoral Response
Cell Migration
Cytokine Activity
Leukocyte Chemotaxis
Cell Motility
Inflammatory Response
Humoral Immune Response
Leukocyte Migration
Granulocyte Chemotaxis
Myeloid Leukocyte Migration
Granulocyte Migration
Cytokine-mediated Signaling Pathway
Immune Response
Killing Of Cells Of Another Organism
Defense Response
Cell Killing
Defense Response To Symbiont
Defense Response To Other Organism
Immune System Process
Response To Stress
CXCR Chemokine Receptor Binding
G Protein-coupled Receptor Signaling Pathway
Signal Transduction
Response To Other Organism
CCR Chemokine Receptor Binding
Response To External Biotic Stimulus
Extracellular Space
Cell Surface Receptor Signaling Pathway
Positive Regulation Of Cell Migration
Positive Regulation Of Cell Motility
Regulation Of Cell Migration
Eosinophil Chemotaxis
Mononuclear Cell Migration
Extracellular Region
Positive Regulation Of Locomotion
Eosinophil Migration
Regulation Of Cell Motility
Regulation Of Locomotion
Regulation Of Leukocyte Migration
Neutrophil Chemotaxis
Chemokine Receptor Binding
C-C Chemokine Binding
Neutrophil Migration
Positive Regulation Of Leukocyte Migration
Chemokine Receptor Activity
Chemokine-mediated Signaling Pathway
Dendritic Cell Migration
Dendritic Cell Chemotaxis
C-C Chemokine Binding
C-C Chemokine Receptor Activity
Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity
Chemokine (C-C Motif) Ligand 5 Binding
Positive Regulation Of Cytosolic Calcium Ion Concentration
Cytokine-mediated Signaling Pathway
Cell Chemotaxis
Response To Cytokine
Response To Peptide
Negative Regulation Of Macrophage Apoptotic Process
Chemotaxis
Mononuclear Cell Migration
G Protein-coupled Receptor Signaling Pathway
Locomotion
G Protein-coupled Receptor Activity
Cellular Response To Cytokine Stimulus
Leukocyte Chemotaxis
Positive Regulation Of Neuroinflammatory Response
Negative Regulation Of Myeloid Cell Apoptotic Process
Positive Regulation Of Monocyte Chemotaxis
Monocyte Chemotaxis
Calcium-mediated Signaling
Inflammatory Response
Regulation Of Monocyte Chemotaxis
Regulation Of Myeloid Cell Apoptotic Process
Immune Response
Cell-cell Signaling
Leukocyte Migration
Regulation Of Neuroinflammatory Response
Signaling
Calcium Ion Transport
Cell Communication
Negative Regulation Of Viral Genome Replication
Defense Response
G Protein-coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger
Negative Regulation Of Leukocyte Apoptotic Process
Coreceptor Activity
Chemokine Receptor Antagonist Activity
Chemokine (C-C Motif) Ligand 5 Signaling Pathway
CCR4 Chemokine Receptor Binding
Intracellular Signaling Cassette
External Side Of Plasma Membrane
Negative Regulation Of Viral Process
Regulation Of Viral Genome Replication
Cell Migration
Chemokine (C-C Motif) Ligand 7 Binding
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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