CCL24 and CCR3

Number of citations of the paper that reports this interaction (PMID 12218106)
9

Data Source:
HPRD (in vitro, in vivo)

		CCL24	CCR3
Gene Name		chemokine (C-C motif) ligand 24	chemokine (C-C motif) receptor 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space	Plasma Membrane Integral Component Of Plasma Membrane
	Molecular Function	Chemokine Activity	Chemokine Receptor Activity Protein Binding C-C Chemokine Receptor Activity
	Biological Process	Positive Regulation Of Endothelial Cell Proliferation Chemotaxis Inflammatory Response Immune Response Cytoskeleton Organization Signal Transduction Cell-cell Signaling Regulation Of Cell Shape Positive Regulation Of Cell Migration Positive Regulation Of Actin Filament Polymerization Positive Regulation Of Rac GTPase Activity Positive Regulation Of Angiogenesis Eosinophil Chemotaxis Positive Regulation Of Inflammatory Response Positive Regulation Of Eosinophil Migration	Positive Regulation Of Endothelial Cell Proliferation Chemotaxis Inflammatory Response Cellular Defense Response Cell Adhesion Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Viral Process Positive Regulation Of Angiogenesis Chemokine-mediated Signaling Pathway
Pathways			Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Signaling by GPCR GPCR downstream signaling Peptide ligand-binding receptors Chemokine receptors bind chemokines Class A/1 (Rhodopsin-like receptors) G alpha (i) signalling events Metabolic disorders of biological oxidation enzymes GPCR ligand binding
Drugs
Diseases
GWAS			Behcet's disease ( 23291587) Celiac disease ( 20190752 18311140) Monocyte chemoattractant protein-1 ( 23017229) Obesity-related traits ( 23251661)
Protein-Protein Interactions		1 interactors: CCR3	19 interactors: CCL11 CCL13 CCL14 CCL15 CCL2 CCL24 CCL26 CCL28 CCL3 CCL3L1 CCL4 CCL5 CCL7 CCL8 CXCL10 CXCL11 CXCL9 FGR HCK
Entrez ID		6369	1232
HPRD ID		03931	03167
Ensembl ID			ENSG00000183625
Uniprot IDs		O00175	P51677 Q8TDP4 Q8TDP5
PDB IDs		1EIG 1EIH
Enriched GO Terms of Interacting Partners?		Cellular Defense Response Chemokine-mediated Signaling Pathway Positive Regulation Of Endothelial Cell Proliferation Regulation Of Endothelial Cell Proliferation Positive Regulation Of Angiogenesis Adenylate Cyclase-modulating G-protein Coupled Receptor Signaling Pathway G-protein Coupled Receptor Signaling Pathway, Coupled To Cyclic Nucleotide Second Messenger Positive Regulation Of Epithelial Cell Proliferation Positive Regulation Of Cytosolic Calcium Ion Concentration Cytosolic Calcium Ion Homeostasis Regulation Of Angiogenesis Regulation Of Epithelial Cell Proliferation Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Cellular Metal Ion Homeostasis Inflammatory Response Cellular Cation Homeostasis Cytokine-mediated Signaling Pathway Cellular Ion Homeostasis Metal Ion Homeostasis Cellular Chemical Homeostasis Viral Process Ion Homeostasis Cellular Response To Cytokine Stimulus Chemotaxis	Cell Chemotaxis Cell Migration Cell Motility Chemotaxis Locomotion Immune Response Movement Of Cell Or Subcellular Component Inflammatory Response Response To External Stimulus Immune System Process Leukocyte Chemotaxis Regulation Of Leukocyte Migration Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Leukocyte Migration Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Eosinophil Chemotaxis Positive Regulation Of Leukocyte Migration Defense Response Eosinophil Migration Regulation Of Cell Migration Regulation Of Cell Motility Regulation Of Locomotion Positive Regulation Of Leukocyte Chemotaxis Regulation Of Cellular Component Movement Cellular Calcium Ion Homeostasis Calcium Ion Homeostasis Positive Regulation Of Chemotaxis Granulocyte Chemotaxis Positive Regulation Of Behavior Regulation Of Chemotaxis Regulation Of Lymphocyte Migration Cellular Metal Ion Homeostasis Regulation Of Cell Shape Cellular Cation Homeostasis Cell-cell Signaling Cellular Ion Homeostasis Positive Regulation Of Calcium Ion Transport Metal Ion Homeostasis Regulation Of Behavior Response To Other Organism Lymphocyte Chemotaxis Positive Regulation Of Natural Killer Cell Chemotaxis Response To Biotic Stimulus T Cell Migration Cellular Chemical Homeostasis Ion Homeostasis Positive Regulation Of Immune System Process Regulation Of Immune System Process
Tagcloud ?		analyze ccl11 chemokines cognitive cxcl10 depressive disability drawn eotaxin great hoehn hypothesized immunosorbent ip mcp mood nonmotor parkinson pd performance pilot positively preliminary staging subjected symptoms worse yahr	basophil basophils c5a ccr2 chains chemoattractant chemotactic continuous continuously cxcr1 cxcr2 eotaxin express fmlp formyl granulocyte hardly leu leukotrienes lt ltc4 macrophage mcp mcp1 mediate migratory phe unrelated weakly
Tagcloud (Difference) ?		analyze ccl11 chemokines cognitive cxcl10 depressive disability drawn great hoehn hypothesized immunosorbent ip mood nonmotor parkinson pd performance pilot positively preliminary staging subjected symptoms worse yahr	basophil basophils c5a ccr2 chains chemoattractant chemotactic continuous continuously cxcr1 cxcr2 express fmlp formyl granulocyte hardly leu leukotrienes lt ltc4 macrophage mcp1 mediate migratory phe unrelated weakly
Tagcloud (Intersection) ?		eotaxin mcp