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RPS28 and CTBP2
Number of citations of the paper that reports this interaction (PubMedID
21988832
)
38
Data Source:
BioGRID
(two hybrid)
RPS28
CTBP2
Description
ribosomal protein S28
C-terminal binding protein 2
Image
GO Annotations
Cellular Component
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Endoplasmic Reticulum
Rough Endoplasmic Reticulum
Cytosol
Ribosome
Small Ribosomal Subunit
Cytosolic Ribosome
Cytosolic Small Ribosomal Subunit
Small-subunit Processome
Synapse
Extracellular Exosome
Cytoplasmic Side Of Rough Endoplasmic Reticulum Membrane
Ribonucleoprotein Complex
Nucleus
Transcription Repressor Complex
Synapse
Molecular Function
RNA Binding
Structural Constituent Of Ribosome
Protein Binding
Transcription Coregulator Binding
Transcription Corepressor Binding
Transcription Coactivator Activity
Transcription Corepressor Activity
Protein Binding
Oxidoreductase Activity
Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor
Protein Kinase Binding
Identical Protein Binding
Protein-containing Complex Binding
NAD Binding
DNA-binding Transcription Factor Binding
Biological Process
Ribosomal Small Subunit Assembly
Cytoplasmic Translation
RRNA Processing
Translation
Maturation Of SSU-rRNA
Ribosome Biogenesis
Ribosomal Small Subunit Biogenesis
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Cell Population Proliferation
Viral Genome Replication
Cell Differentiation
Negative Regulation Of DNA-templated Transcription
Positive Regulation Of Transcription By RNA Polymerase II
Positive Regulation Of Retinoic Acid Receptor Signaling Pathway
White Fat Cell Differentiation
Pathways
L13a-mediated translational silencing of Ceruloplasmin expression
Peptide chain elongation
SRP-dependent cotranslational protein targeting to membrane
SRP-dependent cotranslational protein targeting to membrane
Viral mRNA Translation
Selenocysteine synthesis
Major pathway of rRNA processing in the nucleolus and cytosol
Translation initiation complex formation
Formation of a pool of free 40S subunits
Formation of the ternary complex, and subsequently, the 43S complex
Ribosomal scanning and start codon recognition
GTP hydrolysis and joining of the 60S ribosomal subunit
Eukaryotic Translation Termination
Regulation of expression of SLITs and ROBOs
Response of EIF2AK4 (GCN2) to amino acid deficiency
SARS-CoV-1 modulates host translation machinery
SARS-CoV-2 modulates host translation machinery
Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
PELO:HBS1L and ABCE1 dissociate a ribosome on a non-stop mRNA
ZNF598 and the Ribosome-associated Quality Trigger (RQT) complex dissociate a ribosome stalled on a no-go mRNA
Repression of WNT target genes
Signaling by TCF7L2 mutants
Negative Regulation of CDH1 Gene Transcription
Drugs
Artenimol
Diseases
GWAS
Adult body size (
32376654
)
Age-related cognitive decline (visuospatial skill) (slope of z-scores) (
30954325
)
Age-related hearing impairment (
34108613
)
Apolipoprotein A1 levels (
32203549
)
Body mass index (
25673413
29273807
)
Body size at age 10 (
32376654
)
Brain morphology (MOSTest) (
32665545
)
Chronotype (
30696823
)
Diastolic blood pressure (
30224653
)
Haemorrhoidal disease (
33888516
)
HDL cholesterol levels (
32203549
)
Height (
25429064
)
Hemoglobin levels (
32327693
)
Hip circumference adjusted for BMI (
34021172
)
Infant, child and juvenile death in continuous marriage (proportion of children died <15 years) (
30188897
)
Menarche (age at onset) (
25231870
)
Oily fish consumption (
32066663
)
Pork consumption (
32066663
)
Prostate cancer (
18264096
)
Red blood cell count (
32888494
)
Refractive error (
32231278
)
Vigorous physical activity (
29899525
)
Walking pace (
33128006
)
Interacting Genes
19 interacting genes:
CCNDBP1
CEBPA
CTBP2
DMRTB1
EEF1G
EXOSC8
HMGB2
HSF2BP
KRTAP1-1
KRTAP10-3
KRTAP10-7
KRTAP10-8
KRTAP2-4
KRTAP4-12
NOTCH2NLA
PFDN1
RBFOX2
UNKL
WEE2-AS1
96 interacting genes:
ACTG1
AKTIP
APP
BAZ2B
BCAS3
BCL3
BIRC2
BIRC3
C15orf39
CACNB1
CACNB2
CACNB3
CACNB4
CAPN7
CASP8AP2
CATSPER1
CBX4
CCDC120
CCNH
CCR5
CDKN2A
CEP68
CSTF2
CTBP1
CTPS2
DCAF6
DMRTB1
DTNB
DUSP21
DVL2
EEF1D
EGLN3
EIF4G1
ELAC2
ENKD1
EP300
FHL3
FLI1
FUNDC1
GLIS2
H3-4
HEMGN
HIC1
HOXA5
HOXB5
HOXC5
IKZF2
KCNIP3
KLF3
KLF8
KYNU
LCORL
LMO4
MDM2
MECOM
NEK6
NOL4
NOL4L
NRIP1
PLCB1
PNN
PPP1R15A
PROX1
PSMF1
QARS1
RAI2
RBBP8NL
RIMBP3
RNF135
RPL17
RPL7A
RPS28
RPS29
RPS4X
SDCBP
SHISA6
SOX6
STUB1
STX11
TEAD3
TGIF1
TLE5
TRIML2
TSHZ3
UBC
UBE2I
VRTN
XRCC6
ZBP1
ZEB1
ZEB2
ZFPM1
ZFPM2
ZNF512B
ZNF750
ZSCAN4
Entrez ID
6234
1488
HPRD ID
04731
04016
Ensembl ID
ENSG00000233927
ENSG00000175029
Uniprot IDs
B2R4R9
P62857
P56545
PDB IDs
4UG0
4V6X
5A2Q
5AJ0
5FLX
5LKS
5OA3
5T2C
5VYC
6FEC
6G18
6G4S
6G4W
6G51
6G53
6G5H
6G5I
6IP5
6IP6
6IP8
6OLE
6OLF
6OLG
6OLI
6OLZ
6OM0
6OM7
6QZP
6XA1
6Y0G
6Y2L
6Y57
6YBS
6Z6L
6Z6M
6Z6N
6ZLW
6ZM7
6ZME
6ZMI
6ZMO
6ZMT
6ZMW
6ZN5
6ZOJ
6ZOL
6ZON
6ZP4
6ZUO
6ZV6
6ZVH
6ZVJ
6ZXD
6ZXE
6ZXF
6ZXG
6ZXH
7A09
7K5I
7MQ8
7MQ9
7MQA
7QP6
7QP7
7R4X
7TQL
7WTT
7WTU
7WTV
7WTW
7WTX
7WTZ
7WU0
7XNX
7XNY
8G5Y
8G5Z
8G60
8G61
8G6J
8GLP
8IFD
8IFE
8JDJ
8JDK
8JDL
8JDM
8K2C
8OZ0
8PJ1
8PJ2
8PJ3
8PJ4
8PJ5
8PJ6
8PPK
8PPL
8QOI
8RG0
8T4S
8UKB
8XP2
8XP3
8XSX
8XSY
8XSZ
8XXL
8XXM
8XXN
8Y0W
8Y0X
8YOO
8YOP
8ZDB
8ZDC
8ZDD
9BKD
9BLN
9C3H
9G8M
9G8O
2OME
4LCJ
6WKW
8ATI
Enriched GO Terms of Interacting Partners
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Keratin Filament
Intermediate Filament
DNA-binding Transcription Factor Binding
White Fat Cell Differentiation
Nucleus
Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of DNA-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Regulation Of DNA-templated Transcription
Regulation Of RNA Biosynthetic Process
Negative Regulation Of RNA Metabolic Process
Negative Regulation Of Nucleobase-containing Compound Metabolic Process
Regulation Of RNA Metabolic Process
Regulation Of Nucleobase-containing Compound Metabolic Process
Negative Regulation Of Transcription By RNA Polymerase II
Regulation Of Primary Metabolic Process
Nucleoplasm
Regulation Of Gene Expression
Regulation Of Macromolecule Biosynthetic Process
Regulation Of Macromolecule Metabolic Process
DNA Binding
Negative Regulation Of Macromolecule Biosynthetic Process
Positive Regulation Of Transcription By RNA Polymerase II
RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
Chromatin
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Macromolecule Metabolic Process
Protein Binding
Positive Regulation Of RNA Biosynthetic Process
Positive Regulation Of DNA-templated Transcription
Regulation Of Metabolic Process
Voltage-gated Calcium Channel Activity
Negative Regulation Of Metabolic Process
Positive Regulation Of RNA Metabolic Process
Positive Regulation Of Macromolecule Biosynthetic Process
Transcription Corepressor Activity
DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific
SUMO Transferase Activity
Positive Regulation Of Biosynthetic Process
Positive Regulation Of Macromolecule Metabolic Process
Voltage-gated Calcium Channel Complex
Positive Regulation Of Nucleobase-containing Compound Metabolic Process
L-type Voltage-gated Calcium Channel Complex
Positive Regulation Of Metabolic Process
Apoptotic Process
Positive Regulation Of Signal Transduction By P53 Class Mediator
High Voltage-gated Calcium Channel Activity
Programmed Cell Death
Protein K63-linked Ubiquitination
Cell Death
Regulation Of Signal Transduction By P53 Class Mediator
Monoatomic Ion Channel Complex
Voltage-gated Calcium Channel Activity Involved In Regulation Of Presynaptic Cytosolic Calcium Levels
DNA-binding Transcription Factor Activity, RNA Polymerase II-specific
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