COX6A2 and MRPL12

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		COX6A2	MRPL12
Gene Name		cytochrome c oxidase subunit VIa polypeptide 2	mitochondrial ribosomal protein L12
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrial Respiratory Chain Complex IV	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Large Ribosomal Subunit
	Molecular Function	Cytochrome-c Oxidase Activity	RNA Binding Structural Constituent Of Ribosome Protein Binding
	Biological Process	Generation Of Precursor Metabolites And Energy Hydrogen Ion Transmembrane Transport	Transcription From Mitochondrial Promoter Organelle Organization Mitochondrial Translation Positive Regulation Of Transcription, DNA-templated Mitochondrial Translational Initiation Mitochondrial Translational Elongation Mitochondrial Translational Termination
Pathways			Mitochondrial translation Organelle biogenesis and maintenance Mitochondrial translation elongation Mitochondrial translation initiation Mitochondrial translation termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP COL6A2 MRPL12 POT1 SNX21	5 interactors: COX6A2 OLIG1 POLR1D RARG TMEM51
Entrez ID		1339	6182
HPRD ID		03598	03849
Ensembl ID		ENSG00000156885	ENSG00000262814
Uniprot IDs		Q02221	P52815
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of DNA Strand Elongation Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury Telomere Formation Via Telomerase Collateral Sprouting Axon Midline Choice Point Recognition Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Telomere Capping Positive Regulation Of Helicase Activity Negative Regulation Of Telomere Maintenance Via Telomerase Axon Choice Point Recognition Positive Regulation Of Telomerase Activity Telomere Assembly Positive Regulation Of Telomere Maintenance Via Telomerase Neuron Remodeling Negative Regulation Of Telomerase Activity Telomere Maintenance Via Telomerase Negative Regulation Of Telomere Maintenance Transcription From Mitochondrial Promoter Positive Regulation Of Telomere Maintenance Regulation Of Telomere Maintenance Via Telomerase Positive Regulation Of Macromolecule Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization Protein Heterotrimerization Axon Guidance Positive Regulation Of Cellular Biosynthetic Process Regulation Of Telomerase Activity Cellular Copper Ion Homeostasis Regulation Of Telomere Maintenance Positive Regulation Of DNA Biosynthetic Process Cellular Component Assembly RNA-dependent DNA Replication Copper Ion Homeostasis Suckling Behavior Axonogenesis Negative Regulation Of DNA Biosynthetic Process Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Telomere Maintenance Via Telomere Lengthening Neuron Projection Morphogenesis Mating Behavior Protein Trimerization Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation	Growth Plate Cartilage Chondrocyte Growth Growth Plate Cartilage Chondrocyte Development Harderian Gland Development Chondrocyte Hypertrophy DNA-templated Transcription, Initiation Growth Plate Cartilage Chondrocyte Differentiation Retinal Pigment Epithelium Development Lacrimal Gland Development
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