RORB and PNRC2

Number of citations of the paper that reports this interaction (PMID 15604093)
36

Data Source:
HPRD (two hybrid)

		RORB	PNRC2
Gene Name		RAR-related orphan receptor B	proline-rich nuclear receptor coactivator 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm	Cytoplasmic MRNA Processing Body Nucleus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Steroid Hormone Receptor Activity Ligand-activated Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity Protein Binding Transcription Factor Binding Zinc Ion Binding Sequence-specific DNA Binding	Protein Binding
	Biological Process	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Visual Perception Gene Expression Intracellular Receptor Signaling Pathway Amacrine Cell Differentiation Eye Photoreceptor Cell Development Regulation Of Circadian Rhythm Steroid Hormone Mediated Signaling Pathway Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Retinal Rod Cell Development Retinal Cone Cell Development Rhythmic Process Retina Development In Camera-type Eye Cellular Response To Retinoic Acid	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Transcription, DNA-templated Regulation Of Transcription, DNA-templated Deadenylation-independent Decapping Of Nuclear-transcribed MRNA
Pathways
Drugs
Diseases
GWAS		Refractive error ( 23396134) Visceral adipose tissue/subcutaneous adipose tissue ratio ( 22589738)	Obesity-related traits ( 23251661)
Protein-Protein Interactions		16 interactors: EIF3I MAP6 NCOA1 NCOA6 NME1 NME2 NPPA NRIP1 NRIP2 NSD1 PNRC1 PNRC2 PSMC4 SRC TNNI2 UBE2I	20 interactors: AR DCP1A ESR1 ESR2 ESRRA ESRRG GLOD4 HNF4A HNF4G NR5A1 NR5A2 RARA RARG RORA RORB SF1 SPAG9 XRCC6 ZBTB16 ZBTB48
Entrez ID		6096	55629
HPRD ID		09062	17871
Ensembl ID		ENSG00000198963	ENSG00000189266
Uniprot IDs		Q58EY0	Q9NPJ4
PDB IDs			4B6H
Enriched GO Terms of Interacting Partners?		Intracellular Steroid Hormone Receptor Signaling Pathway Gene Expression Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process RNA Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Small Molecule Interconversion Cellular Nitrogen Compound Metabolic Process Regulation Of Metabolic Process RNA Metabolic Process Intracellular Estrogen Receptor Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression GTP Biosynthetic Process UTP Biosynthetic Process Nucleobase-containing Compound Metabolic Process Purine Nucleotide Biosynthetic Process GTP Metabolic Process UTP Metabolic Process Ribose Phosphate Biosynthetic Process CTP Biosynthetic Process Heterocycle Metabolic Process Nucleoside Diphosphate Phosphorylation Cellular Aromatic Compound Metabolic Process Regulation Of Cellular Process Reproductive Structure Development Cellular Metabolic Process Reproductive System Development Response To Hormone Peptidyl-amino Acid Modification Androgen Receptor Signaling Pathway Pyrimidine Ribonucleotide Biosynthetic Process Cellular Response To Fatty Acid Pyrimidine Nucleoside Biosynthetic Process Response To Progesterone	Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Cellular Response To Steroid Hormone Stimulus Transcription Initiation From RNA Polymerase II Promoter Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Cellular Response To Organic Cyclic Compound Cellular Response To Lipid Response To Steroid Hormone Cellular Response To Hormone Stimulus Transcription From RNA Polymerase II Promoter Response To Lipid Response To Organic Cyclic Compound Response To Hormone Positive Regulation Of Transcription, DNA-templated Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process RNA Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Gene Expression Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Cellular Response To Organic Substance Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nitrogen Compound Metabolic Process Organ Development Response To Organic Substance Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process System Development Developmental Process Involved In Reproduction Prostate Gland Development Sex Differentiation Multicellular Organismal Development Anatomical Structure Development Regulation Of Metabolic Process
Tagcloud ?		agt ass1 beadchip benjamini crym differentiates egr2 folr3 gja1 hochberg hrasls humanref illumina leiomyosarcoma lms lmss masp1 nlgn1 nlgn4x ostn shmt1 slitrk4 tdo2 thbs1 tnnt1 tspan10 tspan7 uterine xrn2	2d af alternatives biologically circular coactivators cognate competitive confirms constitutes coregulator coregulators dichroism ecd eralpha eralpha17p exception exhaustive governing grb2 issued motifs polyproline ppii pxxp sh3 spectroscopy transductions
Tagcloud (Difference) ?		agt ass1 beadchip benjamini crym differentiates egr2 folr3 gja1 hochberg hrasls humanref illumina leiomyosarcoma lms lmss masp1 nlgn1 nlgn4x ostn shmt1 slitrk4 tdo2 thbs1 tnnt1 tspan10 tspan7 uterine xrn2	2d af alternatives biologically circular coactivators cognate competitive confirms constitutes coregulator coregulators dichroism ecd eralpha eralpha17p exception exhaustive governing grb2 issued motifs polyproline ppii pxxp sh3 spectroscopy transductions
Tagcloud (Intersection) ?