TNFRSF17 and TNFSF13B

Number of citations of the paper that reports this interaction (PMID 10801128)
170

Data Source:
HPRD (in vivo, in vitro)

		TNFRSF17	TNFSF13B
Gene Name		tumor necrosis factor receptor superfamily, member 17	tumor necrosis factor (ligand) superfamily, member 13b
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Endomembrane System Integral Component Of Membrane	Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Receptor Activity	Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	Immune System Process Signal Transduction Multicellular Organismal Development Cell Proliferation	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Immune Response Signal Transduction Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Positive Regulation Of T Cell Proliferation Immunoglobulin Secretion
Pathways
Drugs			1,4-Diethylene Dioxide Citric Acid Belimumab
Diseases
GWAS		QT interval ( 19305408)
Protein-Protein Interactions		5 interactors: TNFSF13 TNFSF13B TRAF1 TRAF2 TRAF3	5 interactors: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13
Entrez ID		608	10673
HPRD ID		00144	04914
Ensembl ID		ENSG00000048462	ENSG00000102524
Uniprot IDs		Q02223	Q9Y275
PDB IDs		1OQD 1XU2 2KN1	1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 1OTZ 3V56
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Germinal Center Formation Positive Regulation Of Adaptive Immune Response Positive Regulation Of Immune Response Regulation Of Germinal Center Formation Regulation Of Adaptive Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Cell Activation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Immune Response Regulation Of Lymphocyte Activation Regulation Of Immune System Process Immunoglobulin Production TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Cell Activation MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of B Cell Activation Toll-like Receptor 4 Signaling Pathway Cellular Response To Tumor Necrosis Factor Toll-like Receptor Signaling Pathway Response To Tumor Necrosis Factor Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Immune System Process Activation Of Innate Immune Response Signal Transduction Positive Regulation Of Innate Immune Response B Cell Costimulation Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Programmed Cell Death Positive Regulation Of T Cell Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Signaling Positive Regulation Of Homotypic Cell-cell Adhesion Cell Death Death Cell Communication Immunoglobulin Production In Mucosal Tissue Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Immunoglobulin Secretion Positive Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of Glial Cell Apoptotic Process Regulation Of T Cell Activation Cellular Response To Stimulus Positive Regulation Of Protein Homodimerization Activity	Positive Regulation Of Germinal Center Formation Regulation Of Germinal Center Formation Immune System Process B Cell Homeostasis Regulation Of Lymphocyte Activation Regulation Of B Cell Proliferation Regulation Of Cell Activation Lymphocyte Homeostasis Positive Regulation Of B Cell Activation Leukocyte Homeostasis Positive Regulation Of Adaptive Immune Response Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury B Cell Costimulation Regulation Of Adaptive Immune Response Collateral Sprouting Axon Midline Choice Point Recognition Immunoglobulin Production In Mucosal Tissue Homeostasis Of Number Of Cells Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Isotype Switching To IgA Isotypes Axon Choice Point Recognition Regulation Of Immune System Process Positive Regulation Of Cell Activation Homeostatic Process Neuron Remodeling Regulation Of Cell Proliferation Positive Regulation Of Interferon-gamma Biosynthetic Process Negative Regulation Of B Cell Proliferation Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Isotype Switching Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mucosal Immune Response Regulation Of Isotype Switching Positive Regulation Of Immune Response Mating Behavior Positive Regulation Of Immunoglobulin Mediated Immune Response Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Positive Regulation Of Immunoglobulin Production Negative Regulation Of B Cell Activation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response
Tagcloud ?		assayed buck chose clic5 conditional cxcl13 dichotomization dichotomous dr ffpe hrneg hrpos ics incorporating microarray multigene multiplexed nodal optimized platforms prognostically proved reaffirmed rtpcr signatures subtyping tneg today xcl2	17a 23r arntl atf5 ccl20 ccr6 cd40lg ceacam1 covert ctsh cxcr6 faslg furin isg20 ltb map3k4 mcam permissiveness ppargamma pseudotyped ptk2 ptpn13 rorc rosiglitazone serpinb6 th1 th1th17 vsv
Tagcloud (Difference) ?		assayed buck chose clic5 conditional cxcl13 dichotomization dichotomous dr ffpe hrneg hrpos ics incorporating microarray multigene multiplexed nodal optimized platforms prognostically proved reaffirmed rtpcr signatures subtyping tneg today xcl2	17a 23r arntl atf5 ccl20 ccr6 cd40lg ceacam1 covert ctsh cxcr6 faslg furin isg20 ltb map3k4 mcam permissiveness ppargamma pseudotyped ptk2 ptpn13 rorc rosiglitazone serpinb6 th1 th1th17 vsv
Tagcloud (Intersection) ?