TNFSF13B and TNFRSF13B

Number of citations of the paper that reports this interaction (PMID 10801128)
170

Data Source:
HPRD (in vivo, in vitro)

		TNFSF13B	TNFRSF13B
Gene Name		tumor necrosis factor (ligand) superfamily, member 13b	tumor necrosis factor receptor superfamily, member 13B
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	Integral Component Of Plasma Membrane External Side Of Plasma Membrane
	Molecular Function	Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding	Receptor Activity Protein Binding
	Biological Process	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Immune Response Signal Transduction Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Positive Regulation Of T Cell Proliferation Immunoglobulin Secretion	B Cell Homeostasis Hematopoietic Progenitor Cell Differentiation Cell Surface Receptor Signaling Pathway Negative Regulation Of B Cell Proliferation
Pathways
Drugs		1,4-Diethylene Dioxide Citric Acid Belimumab
Diseases
GWAS			Diabetic retinopathy ( 21441570) Hematological and biochemical traits ( 20139978) Hematology traits ( 23303382) IgG levels ( 22673310) Non-albumin protein levels ( 22558069) Serum total protein level ( 23022100)
Protein-Protein Interactions		5 interactors: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13	7 interactors: CAMLG SGTA TNFSF13 TNFSF13B TRAF2 TRAF5 TRAF6
Entrez ID		10673	23495
HPRD ID		04914	05365
Ensembl ID		ENSG00000102524	ENSG00000240505
Uniprot IDs		Q9Y275	B7Z6V8 O14836 Q4ACX1
PDB IDs		1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 1OTZ 3V56	1XU1 1XUT
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Germinal Center Formation Regulation Of Germinal Center Formation Immune System Process B Cell Homeostasis Regulation Of Lymphocyte Activation Regulation Of B Cell Proliferation Regulation Of Cell Activation Lymphocyte Homeostasis Positive Regulation Of B Cell Activation Leukocyte Homeostasis Positive Regulation Of Adaptive Immune Response Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury B Cell Costimulation Regulation Of Adaptive Immune Response Collateral Sprouting Axon Midline Choice Point Recognition Immunoglobulin Production In Mucosal Tissue Homeostasis Of Number Of Cells Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Isotype Switching To IgA Isotypes Axon Choice Point Recognition Regulation Of Immune System Process Positive Regulation Of Cell Activation Homeostatic Process Neuron Remodeling Regulation Of Cell Proliferation Positive Regulation Of Interferon-gamma Biosynthetic Process Negative Regulation Of B Cell Proliferation Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Isotype Switching Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mucosal Immune Response Regulation Of Isotype Switching Positive Regulation Of Immune Response Mating Behavior Positive Regulation Of Immunoglobulin Mediated Immune Response Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Positive Regulation Of Immunoglobulin Production Negative Regulation Of B Cell Activation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response	Positive Regulation Of Adaptive Immune Response Regulation Of Adaptive Immune Response Positive Regulation Of Germinal Center Formation Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Cell Activation Regulation Of Immunoglobulin Secretion Regulation Of Germinal Center Formation Positive Regulation Of T Cell Cytokine Production Positive Regulation Of Immune Response Positive Regulation Of T Cell Activation Regulation Of T Cell Cytokine Production Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Activation Of NF-kappaB-inducing Kinase Activity Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of NIK/NF-kappaB Signaling Positive Regulation Of Cell-cell Adhesion Protein K63-linked Ubiquitination Positive Regulation Of Interleukin-2 Production Positive Regulation Of Cell Proliferation NIK/NF-kappaB Signaling Regulation Of NIK/NF-kappaB Signaling Regulation Of Immune Response Protein Autoubiquitination Regulation Of T Cell Activation Positive Regulation Of Immune System Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cytokine Production Involved In Immune Response I-kappaB Kinase/NF-kappaB Signaling Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Immunoglobulin Production TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of JUN Kinase Activity Regulation Of Cytokine Production Involved In Immune Response Positive Regulation Of B Cell Activation Toll-like Receptor 4 Signaling Pathway Regulation Of JUN Kinase Activity Positive Regulation Of T Cell Proliferation Immune Response Regulation Of Immune System Process Positive Regulation Of T Cell Mediated Immunity Toll-like Receptor Signaling Pathway Regulation Of Cell Proliferation Protein Ubiquitination Positive Regulation Of Lymphocyte Proliferation Positive Regulation Of Mononuclear Cell Proliferation
Tagcloud ?		17a 23r arntl atf5 ccl20 ccr6 cd40lg ceacam1 covert ctsh cxcr6 faslg furin isg20 ltb map3k4 mcam permissiveness ppargamma pseudotyped ptk2 ptpn13 rorc rosiglitazone serpinb6 th1 th1th17 vsv	adjusting associations card11 clear consortium correcting determinants endometrioid eoc highlight histologies histology immunity inherited member modulating mucinous note phospholipase plcg1 rs11696662 rs17250239 rs41324349 rs7501462 serous superfamily threshold traf2
Tagcloud (Difference) ?		17a 23r arntl atf5 ccl20 ccr6 cd40lg ceacam1 covert ctsh cxcr6 faslg furin isg20 ltb map3k4 mcam permissiveness ppargamma pseudotyped ptk2 ptpn13 rorc rosiglitazone serpinb6 th1 th1th17 vsv	adjusting associations card11 clear consortium correcting determinants endometrioid eoc highlight histologies histology immunity inherited member modulating mucinous note phospholipase plcg1 rs11696662 rs17250239 rs41324349 rs7501462 serous superfamily threshold traf2
Tagcloud (Intersection) ?