TNFRSF17

Gene Name		tumor necrosis factor receptor superfamily, member 17
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Endomembrane System Integral Component Of Membrane
	Molecular Function	Receptor Activity
	Biological Process	Immune System Process Signal Transduction Multicellular Organismal Development Cell Proliferation
Pathways
Drugs
Diseases
GWAS		QT interval ( 19305408)
Protein-protein Interactions		5 interactors: TNFSF13 TNFSF13B TRAF1 TRAF2 TRAF3
Entrez ID		608
HPRD ID		00144
Ensembl ID		ENSG00000048462
Uniprot IDs		Q02223
PDB IDs		1OQD 1XU2 2KN1
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Germinal Center Formation Positive Regulation Of Adaptive Immune Response Positive Regulation Of Immune Response Regulation Of Germinal Center Formation Regulation Of Adaptive Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Tumor Necrosis Factor-mediated Signaling Pathway Positive Regulation Of Cell Activation Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Immune Response Regulation Of Lymphocyte Activation Regulation Of Immune System Process Immunoglobulin Production TRIF-dependent Toll-like Receptor Signaling Pathway Regulation Of Cell Activation MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Positive Regulation Of B Cell Activation Toll-like Receptor 4 Signaling Pathway Cellular Response To Tumor Necrosis Factor Toll-like Receptor Signaling Pathway Response To Tumor Necrosis Factor Positive Regulation Of NF-kappaB Transcription Factor Activity Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Immune System Process Activation Of Innate Immune Response Signal Transduction Positive Regulation Of Innate Immune Response B Cell Costimulation Apoptotic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Programmed Cell Death Positive Regulation Of T Cell Activation Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Signaling Positive Regulation Of Homotypic Cell-cell Adhesion Cell Death Death Cell Communication Immunoglobulin Production In Mucosal Tissue Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Immunoglobulin Secretion Positive Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of Glial Cell Apoptotic Process Regulation Of T Cell Activation Cellular Response To Stimulus Positive Regulation Of Protein Homodimerization Activity
Tagcloud ?		assayed buck chose clic5 conditional cxcl13 dichotomization dichotomous dr ffpe hrneg hrpos ics incorporating microarray multigene multiplexed nodal optimized platforms prognostically proved reaffirmed rtpcr signatures subtyping tneg today xcl2