TNFSF13B and TNFRSF13C

Number of citations of the paper that reports this interaction (PMID 11509692)
139

Data Source:
HPRD (in vivo, in vitro)

		TNFSF13B	TNFRSF13C
Gene Name		tumor necrosis factor (ligand) superfamily, member 13b	tumor necrosis factor receptor superfamily, member 13C
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Plasma Membrane Integral Component Of Membrane Perinuclear Region Of Cytoplasm	External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Receptor Binding Cytokine Activity Tumor Necrosis Factor Receptor Binding Protein Binding
	Biological Process	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Immune Response Signal Transduction Cell Proliferation Positive Regulation Of Cell Proliferation Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Positive Regulation Of T Cell Proliferation Immunoglobulin Secretion	B Cell Homeostasis Positive Regulation Of Germinal Center Formation Positive Regulation Of B Cell Proliferation T Cell Costimulation B Cell Costimulation Positive Regulation Of T Cell Proliferation Positive Regulation Of Interferon-gamma Biosynthetic Process
Pathways
Drugs		1,4-Diethylene Dioxide Citric Acid Belimumab
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP TNFRSF13B TNFRSF13C TNFRSF17 TNFSF13	2 interactors: TNFSF13B TRAF3
Entrez ID		10673	115650
HPRD ID		04914	05883
Ensembl ID		ENSG00000102524	ENSG00000159958
Uniprot IDs		Q9Y275	Q5H8V1 Q96RJ3
PDB IDs		1JH5 1KD7 1KXG 1OQD 1OQE 1OSG 1OTZ 3V56	1MPV 1OQE 1OSX 1P0T 2HFG
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Germinal Center Formation Regulation Of Germinal Center Formation Immune System Process B Cell Homeostasis Regulation Of Lymphocyte Activation Regulation Of B Cell Proliferation Regulation Of Cell Activation Lymphocyte Homeostasis Positive Regulation Of B Cell Activation Leukocyte Homeostasis Positive Regulation Of Adaptive Immune Response Synaptic Growth At Neuromuscular Junction Collateral Sprouting In Absence Of Injury B Cell Costimulation Regulation Of Adaptive Immune Response Collateral Sprouting Axon Midline Choice Point Recognition Immunoglobulin Production In Mucosal Tissue Homeostasis Of Number Of Cells Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Isotype Switching To IgA Isotypes Axon Choice Point Recognition Regulation Of Immune System Process Positive Regulation Of Cell Activation Homeostatic Process Neuron Remodeling Regulation Of Cell Proliferation Positive Regulation Of Interferon-gamma Biosynthetic Process Negative Regulation Of B Cell Proliferation Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Positive Regulation Of Isotype Switching Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity Mucosal Immune Response Regulation Of Isotype Switching Positive Regulation Of Immune Response Mating Behavior Positive Regulation Of Immunoglobulin Mediated Immune Response Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Positive Regulation Of Immunoglobulin Production Negative Regulation Of B Cell Activation Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Positive Regulation Of B Cell Proliferation Immunoglobulin Production Involved In Immunoglobulin Mediated Immune Response	B Cell Costimulation Immunoglobulin Secretion Positive Regulation Of Germinal Center Formation Positive Regulation Of Immune Response Toll Signaling Pathway Regulation Of Germinal Center Formation Regulation Of Immune Response Positive Regulation Of Immune System Process Tumor Necrosis Factor-mediated Signaling Pathway Immune Response Regulation Of Immune System Process B Cell Homeostasis Regulation Of Interferon-beta Production Positive Regulation Of B Cell Proliferation Negative Regulation Of Type I Interferon Production Regulation Of B Cell Proliferation Negative Regulation Of NF-kappaB Transcription Factor Activity Immunoglobulin Production TRIF-dependent Toll-like Receptor Signaling Pathway MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Lymphocyte Homeostasis Positive Regulation Of B Cell Activation T Cell Costimulation Regulation Of Defense Response To Virus Toll-like Receptor 4 Signaling Pathway Positive Regulation Of T Cell Proliferation Leukocyte Homeostasis Cellular Response To Tumor Necrosis Factor Immune System Process Regulation Of Type I Interferon Production Toll-like Receptor Signaling Pathway Positive Regulation Of Lymphocyte Proliferation Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Mononuclear Cell Proliferation Protein Secretion Response To Tumor Necrosis Factor Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Regulation Of T Cell Proliferation Positive Regulation Of Adaptive Immune Response Positive Regulation Of Innate Immune Response Regulation Of Adaptive Immune Response Negative Regulation Of Cytokine Production Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Homeostasis Of Number Of Cells Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response
Tagcloud ?		17a 23r arntl atf5 ccl20 ccr6 cd40lg ceacam1 covert ctsh cxcr6 faslg furin isg20 ltb map3k4 mcam permissiveness ppargamma pseudotyped ptk2 ptpn13 rorc rosiglitazone serpinb6 th1 th1th17 vsv	activating adjacent baff cascades correlates document encodes encoding germline his159tyr hodgkin immunoglobulin kappab1 kappab2 lymphoma modulate motif mutation recruitment requirement reveals subset substitution tail traf2 traf3 traf6 wt
Tagcloud (Difference) ?		17a 23r arntl atf5 ccl20 ccr6 cd40lg ceacam1 covert ctsh cxcr6 faslg furin isg20 ltb map3k4 mcam permissiveness ppargamma pseudotyped ptk2 ptpn13 rorc rosiglitazone serpinb6 th1 th1th17 vsv	activating adjacent baff cascades correlates document encodes encoding germline his159tyr hodgkin immunoglobulin kappab1 kappab2 lymphoma modulate motif mutation recruitment requirement reveals subset substitution tail traf2 traf3 traf6 wt
Tagcloud (Intersection) ?