NDUFA7 and ELAC2

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
HPRD (two hybrid)

		NDUFA7	ELAC2
Description		NADH:ubiquinone oxidoreductase subunit A7	elaC ribonuclease Z 2
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GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I	Nucleus Nucleoplasm Mitochondrion Mitochondrial Matrix Cytosol Mitochondrial Nucleoid
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	RNA Binding Nuclease Activity Endonuclease Activity RNA Endonuclease Activity TRNA-specific Ribonuclease Activity Hydrolase Activity 3'-tRNA Processing Endoribonuclease Activity Metal Ion Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration ATP Synthesis Coupled Electron Transport Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	TRNA Processing TRNA Decay TRNA 3'-end Processing Mitochondrial TRNA Processing Mitochondrial TRNA 3'-end Processing
Pathways		Respiratory electron transport Complex I biogenesis	tRNA processing in the nucleus tRNA processing in the mitochondrion rRNA processing in the mitochondrion tRNA-derived small RNA (tsRNA or tRNA-related fragment, tRF) biogenesis
Drugs		NADH
Diseases
GWAS			Squamous cell lung carcinoma ( 28604730)
Interacting Genes		8 interacting genes: ELAC2 LMO1 MDFI PRKAB1 RTP2 STARD9 TTPA UPF2	10 interacting genes: ASCC2 CTBP1 CTBP2 CUX1 GOLM1 NDUFA7 RING1 RNF10 SMAD2 SUMO2
Entrez ID		4701	60528
HPRD ID		11885	05641
Ensembl ID		ENSG00000267855	ENSG00000006744
Uniprot IDs		O95182	A0A0S2Z5M8 Q9BQ52
PDB IDs		5XTB 5XTD 5XTH 5XTI	8CBL 8RR1 8RR3 8RR4 8Z0P 8Z1F 8Z1G 9EY0 9EY1 9EY2
Enriched GO Terms of Interacting Partners?			Ribosome-associated Ubiquitin-dependent Protein Catabolic Process White Fat Cell Differentiation Viral Genome Replication Regulation Of DNA-templated Transcription NAD Binding DNA-binding Transcription Factor Binding Regulation Of RNA Biosynthetic Process Transcription Coregulator Binding Regulation Of RNA Metabolic Process Transcription Corepressor Binding Oxidoreductase Activity, Acting On The CH-OH Group Of Donors, NAD Or NADP As Acceptor Transcription Repressor Complex Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Primary Metabolic Process Negative Regulation Of RNA Biosynthetic Process Homomeric SMAD Protein Complex Negative Regulation Of RNA Metabolic Process Zygotic Specification Of Dorsal/ventral Axis Activin Responsive Factor Complex Paraxial Mesoderm Morphogenesis Ubiquitin Protein Ligase Activity Cytosolic Ribosome RQC-trigger Complex GABA-ergic Synapse Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Ubiquitin Ligase Complex
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