NDUFA7 and PRKAB1

Number of citations: 0 (PubMedID 16169070)
Data Source: BioGRID (two hybrid), HPRD (two hybrid)

		NDUFA7	PRKAB1
Name		NADH:ubiquinone oxidoreductase subunit A7	protein kinase AMP-activated non-catalytic subunit beta 1
Structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Inner Membrane Membrane Respiratory Chain Complex I	Nucleus Nucleoplasm Cytoplasm Cytosol Nucleotide-activated Protein Kinase Complex Protein-containing Complex
	Molecular Function	Protein Binding NADH Dehydrogenase (ubiquinone) Activity	Protein Binding Protein Kinase Binding
	Biological Process	Mitochondrial Electron Transport, NADH To Ubiquinone Aerobic Respiration ATP Synthesis Coupled Electron Transport Proton Motive Force-driven Mitochondrial ATP Synthesis Proton Transmembrane Transport	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Signal Transduction Cellular Response To Nutrient Levels Nail Development Positive Regulation Of Cold-induced Thermogenesis
Pathways		Respiratory electron transport Complex I biogenesis	Translocation of SLC2A4 (GLUT4) to the plasma membrane Macroautophagy Activation of PPARGC1A (PGC-1alpha) by phosphorylation Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes Regulation of TP53 Activity through Phosphorylation Lipophagy Activation of AMPK downstream of NMDARs AMPK-induced ERAD and lysosome mediated degradation of PD-L1(CD274)
Drugs		NADH	Adenosine phosphate Adenosine phosphate Metformin Acetylsalicylic acid Fostamatinib
GWAS		No GWAS studies recorded	Basophil count ( 32888494 ) Inflammatory bowel disease ( 26192919 ) Lymphocyte percentage of white cells ( 32888494 ) Mitochondrial heteroplasmy measurement ( 33731350 ) Monocyte count ( 32888494 ) Neutrophil count ( 32888494 ) Plateletcrit ( 32888494 ) Ulcerative colitis ( 26192919 ) White blood cell count ( 32888494 )
Interacting Genes		8 interacting genes: ELAC2 LMO1 MDFI PRKAB1 RTP2 STARD9 TTPA UPF2	13 interacting genes: ACACA AGL APP F10 GRB2 MAP3K7 MAPK6 NDUFA7 PRKAA1 PRKAA2 PRKAG1 PRKAG2 SLC31A1
Entrez ID		4701	5564
HPRD ID		11885	04116
Ensembl ID		ENSG00000267855	ENSG00000111725
Uniprot IDs		O95182	Q9Y478
PDB IDs		5XTB 5XTD 5XTH 5XTI	4CFE 4CFF 4ZHX 5EZV 5ISO 6B1U 6C9F 6C9G 6C9H 6C9J 7MYJ 8BIK
GO Terms Enriched among Interactors		None	AMP-activated Protein Kinase Activity Nucleotide-activated Protein Kinase Complex Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Regulation Of ATP Metabolic Process Regulation Of Purine Nucleotide Metabolic Process Fatty Acid Biosynthetic Process Regulation Of Generation Of Precursor Metabolites And Energy Cellular Response To Glucose Starvation Positive Regulation Of Small Molecule Metabolic Process Cellular Response To Prostaglandin E Stimulus Positive Regulation Of Glycolytic Process Histone H2BS36 Kinase Activity [hydroxymethylglutaryl-CoA Reductase (NADPH)] Kinase Activity Cellular Response To Prostaglandin Stimulus Carboxylic Acid Biosynthetic Process Response To Prostaglandin E Phosphate-containing Compound Metabolic Process Regulation Of Carbon Utilization Fatty Acid Metabolic Process Regulation Of Phosphorus Metabolic Process Positive Regulation Of ATP Metabolic Process Regulation Of Small Molecule Metabolic Process Protein Localization To Lipid Droplet Sterol Biosynthetic Process Negative Regulation Of Tubulin Deacetylation CAMP-dependent Protein Kinase Activity Negative Regulation Of Hepatocyte Apoptotic Process Cellular Response To Starvation Regulation Of Tubulin Deacetylation Lipid Droplet Disassembly CAMP-dependent Protein Kinase Regulator Activity Small Molecule Biosynthetic Process Protein Kinase Binding Monocarboxylic Acid Metabolic Process Response To Starvation Response To Nutrient Levels Phosphatidylethanolamine Biosynthetic Process ATP Binding Organophosphate Biosynthetic Process Lipid Biosynthetic Process Regulation Of Protein Deacetylation Regulation Of Stress Granule Assembly Cellular Response To Nutrient Levels Steroid Biosynthetic Process AMP Binding Positive Regulation Of TOR Signaling Response To Hormone Intracellular Copper Ion Homeostasis Protein Kinase Regulator Activity