RN7SL1 and STRAP

Number of citations of the paper that reports this interaction (PubMedID 23221635)
111

Data Source:
BioGRID (unspecified method)

		RN7SL1	STRAP
Description		RNA component of signal recognition particle 7SL1	serine/threonine kinase receptor associated protein
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Signal Recognition Particle, Endoplasmic Reticulum Targeting	Nucleus Cytoplasm Cytosol SMN Complex SMN-Sm Protein Complex
	Molecular Function		RNA Binding MRNA Binding Signaling Receptor Binding Protein Binding U2 SnRNP Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition	Negative Regulation Of Transcription By RNA Polymerase II Alternative MRNA Splicing, Via Spliceosome Spliceosomal SnRNP Assembly MRNA Splicing, Via Spliceosome MRNA Processing RNA Splicing Protein-RNA Complex Assembly Neuron Differentiation Maintenance Of Gastrointestinal Epithelium Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Pathways			Downregulation of TGF-beta receptor signaling Downregulation of TGF-beta receptor signaling Positive Regulation of CDH1 Gene Transcription
Drugs
Diseases
GWAS
Interacting Genes		9 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 SMN1 STRAP	31 interacting genes: ANXA1 CEBPA CHEK2 FOXP1 GEMIN6 GEMIN7 MAP1B MTRES1 NEIL3 NXF1 PBLD PDPK1 PTEN RN7SL1 RNU1-1 RNU2-1 SMAD2 SMAD3 SMAD6 SMAD7 SMN1 SMURF1 SNRPB SNRPD2 SNRPD3 SNRPE SUMO2 SUMO4 SZRD1 TGFBR1 TGFBR2
Entrez ID		6029	11171
HPRD ID			05816
Ensembl ID		ENSG00000276168	ENSG00000023734
Uniprot IDs			Q9Y3F4
PDB IDs
Enriched GO Terms of Interacting Partners?		SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Protein-containing Complex Assembly Nuclear Body RNA Metabolic Process Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions Nucleic Acid Metabolic Process Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Cytosol Nucleoplasm Nucleus Cytoplasm RNA Binding Cajal Body SMN-Gemin2 Complex Sm-like Protein Family Complex U2 SnRNP Binding U4atac SnRNA Binding U4 SnRNA Binding RNA Polymerase II Transcription Repressor Complex U1 SnRNA Binding SnRNA Binding Ribonucleoside Triphosphate Phosphatase Activity RNA 7-methylguanosine Cap Binding MRNA Binding Small Nuclear Ribonucleoprotein Complex Spliceosomal Tri-snRNP Complex Assembly DNA-templated Transcription Termination Maintenance Of Gastrointestinal Epithelium Alternative MRNA Splicing, Via Spliceosome	SMN-Sm Protein Complex I-SMAD Binding Spliceosomal SnRNP Assembly Spliceosomal Complex Assembly Heteromeric SMAD Protein Complex 7-methylguanosine Cap Hypermethylation SMAD Protein Signal Transduction U2 SnRNP Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Protein-RNA Complex Assembly Type I Transforming Growth Factor Beta Receptor Binding U4 SnRNP Response To Growth Factor Methylosome Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Small Nuclear Ribonucleoprotein Complex Cellular Response To Growth Factor Stimulus Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway U1 SnRNP Cell Surface Receptor Protein Serine/threonine Kinase Signaling Pathway U5 SnRNP Regulation Of Epithelial To Mesenchymal Transition RNA Splicing, Via Transesterification Reactions Activin Receptor Binding U2-type Prespliceosome Assembly U12-type Spliceosomal Complex PICln-Sm Protein Complex Nucleoplasm R-SMAD Binding Regulation Of SMAD Protein Signal Transduction Trophoblast Cell Migration U7 SnRNP U2-type Spliceosomal Complex Embryonic Cranial Skeleton Morphogenesis Activin Receptor Signaling Pathway U2-type Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Ureteric Bud Development SMN Complex Ubiquitin Protein Ligase Binding Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Ossification Co-SMAD Binding Gemini Of Cajal Bodies Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway MRNA Splicing, Via Spliceosome Mesonephric Tubule Development Mesonephric Epithelium Development SMAD Binding
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