RN7SL1 and GEMIN2

Number of citations: 111 (PubMedID 23221635)
Data Source: BioGRID (unspecified method)

		RN7SL1	GEMIN2
Name		RNA component of signal recognition particle 7SL1	gem nuclear organelle associated protein 2
Structure		No pdb structure
GO Annotations	Cellular Component	Signal Recognition Particle, Endoplasmic Reticulum Targeting	Nucleus Nucleoplasm Spliceosomal Complex Nucleolus Cytoplasm Cytosol Nuclear Body SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies
	Molecular Function	None	Protein Binding
	Biological Process	SRP-dependent Cotranslational Protein Targeting To Membrane, Signal Sequence Recognition	Spliceosomal Complex Assembly RNA Splicing, Via Transesterification Reactions Spliceosomal SnRNP Assembly MRNA Processing RNA Splicing Protein-containing Complex Assembly
Pathways		None	snRNP Assembly SARS-CoV-2 modulates host translation machinery
GWAS		No GWAS studies recorded	Vitamin D levels ( 28757204 )
Novel Interactors		None recorded	1 novel interactors: AKAP6
Interacting Genes		9 interacting genes: DDX20 GEMIN2 GEMIN4 GEMIN5 GEMIN6 GEMIN7 GEMIN8 SMN1 STRAP	33 interacting genes: BEND7 DDX20 DHX9 FBXO7 GEMIN5 HOXD10 IKBKG INCA1 KPNA6 MEOX1 MTNR1A NUFIP1 PAX6 PSMB1 RN7SL1 RNU1-1 RNU2-1 RPP14 SMN1 SMN2 SNRNP70 SNRPD1 SNRPD2 SNRPD3 SNRPN SPG21 SRSF1 SRSF2 SRSF3 SRSF4 STXBP2 STXBP3 U2AF2
Entrez ID		6029	8487
HPRD ID		Not available	03999
Ensembl ID		ENSG00000276168	ENSG00000092208
Uniprot IDs		Not available	A0A8J9FJK1 A0A8J9FN78 O14893
PDB IDs		Not available	2LEH 5XJL 5XJQ 5XJR 5XJS 5XJT 5XJU
GO Terms Enriched among Interactors		SMN Complex SMN-Sm Protein Complex Gemini Of Cajal Bodies Spliceosomal SnRNP Assembly Protein-RNA Complex Assembly RNA Splicing MRNA Processing MRNA Metabolic Process RNA Processing Protein-containing Complex Assembly Nuclear Body RNA Metabolic Process Protein-containing Complex Organization RNA Splicing, Via Transesterification Reactions Nucleic Acid Metabolic Process Cellular Component Assembly Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Assembly MRNA Splicing, Via Spliceosome Macromolecule Metabolic Process Cytosol Nucleoplasm Nucleus Cytoplasm RNA Binding Cajal Body SMN-Gemin2 Complex Sm-like Protein Family Complex U2 SnRNP Binding U4atac SnRNA Binding U4 SnRNA Binding RNA Polymerase II Transcription Repressor Complex U1 SnRNA Binding SnRNA Binding Ribonucleoside Triphosphate Phosphatase Activity RNA 7-methylguanosine Cap Binding MRNA Binding Small Nuclear Ribonucleoprotein Complex Spliceosomal Tri-snRNP Complex Assembly DNA-templated Transcription Termination Maintenance Of Gastrointestinal Epithelium Alternative MRNA Splicing, Via Spliceosome	RNA Splicing MRNA Processing SMN-Sm Protein Complex Protein-RNA Complex Assembly RNA Splicing, Via Transesterification Reactions RNA Processing MRNA Metabolic Process Spliceosomal SnRNP Assembly RNA Metabolic Process MRNA Splicing, Via Spliceosome U1 SnRNP Spliceosomal Complex Assembly RNA Binding U2 SnRNP SMN Complex U4 SnRNP Nucleoplasm Nucleic Acid Metabolic Process Gemini Of Cajal Bodies Regulation Of MRNA Processing Small Nuclear Ribonucleoprotein Complex Protein-containing Complex Assembly Spliceosomal Complex U5 SnRNP Commitment Complex Regulation Of MRNA Splicing, Via Spliceosome PICln-Sm Protein Complex Protein-containing Complex Organization Nucleobase-containing Compound Metabolic Process 7-methylguanosine Cap Hypermethylation MRNA Binding Catalytic Step 2 Spliceosome U4/U6 X U5 Tri-snRNP Complex Regulation Of RNA Splicing Methylosome Sequence-specific MRNA Binding Regulation Of MRNA Metabolic Process Nucleus U2-type Prespliceosome Nuclear Body DNA-templated Transcription Termination Precatalytic Spliceosome Ribonucleoprotein Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Tertiary Granule Nucleic Acid Binding Cellular Response To Cytokine Stimulus U2-type Prespliceosome Assembly U12-type Spliceosomal Complex Cytoplasmic Ribonucleoprotein Granule