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RGS12 and PM20D2
Number of citations of the paper that reports this interaction (PubMedID
32296183
)
50
Data Source:
BioGRID
(two hybrid)
RGS12
PM20D2
Description
regulator of G protein signaling 12
peptidase M20 domain containing 2
Image
GO Annotations
Cellular Component
Condensed Nuclear Chromosome
Nucleus
Nucleoplasm
Nucleolus
Cytoplasm
Cytosol
Plasma Membrane
Nuclear Matrix
Dendrite
Cell Projection
Synapse
Nucleoplasm
Cytoplasm
Molecular Function
GTPase Activity
GTPase Activator Activity
Protein Binding
GTPase Regulator Activity
Carboxypeptidase Activity
Protein Binding
Peptidase Activity
Hydrolase Activity
Dipeptidase Activity
Identical Protein Binding
Para-aminobenzoyl-glutamate Hydrolase Activity
Biological Process
Signal Transduction
G Protein-coupled Receptor Signaling Pathway
Regulation Of G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Signal Transduction
Proteolysis
Folic Acid Catabolic Process
Regulation Of Protein Metabolic Process
Pathways
G alpha (i) signalling events
G alpha (i) signalling events
Drugs
Diseases
GWAS
Adult body size (
32376654
)
Coronary artery disease (
29212778
)
Creatinine levels (
29403010
)
Estimated glomerular filtration rate (
30604766
31015462
)
Glomerular filtration rate (
29403010
)
Hepatocyte growth factor levels (
25998175
)
Itch intensity from mosquito bite adjusted by bite size (
28199695
)
Medication use (agents acting on the renin-angiotensin system) (
31015401
)
Medication use (HMG CoA reductase inhibitors) (
31015401
)
Platelet count (
29403010
)
Serum albumin levels (
29403010
)
Total cholesterol levels (
29403010
33339817
)
Tuberculosis (
29036319
)
Worry too long after an embarrassing experience (
29500382
)
Serum metabolite levels (
33031748
)
Interacting Genes
17 interacting genes:
ARAF
CACNA1B
CXCR2
EEF1A1
GNAI1
GNAI2
GNAI3
GRM2
GRM5
HRAS
MAP2K2
MTNR1A
NPY2R
PLCB1
PLCB3
PM20D2
YWHAG
24 interacting genes:
CERT1
CNNM3
DALRD3
DDIT4L
DNAJC11
EPDR1
HAPLN2
KEL
KRT75
KRTAP26-1
MEOX1
MYOZ3
NAA80
OGT
POU6F2
PSMA1
REL
RGS12
RP2
RUSC1
SAXO1
SIVA1
TAPBPL
TDO2
Entrez ID
6002
135293
HPRD ID
03943
16473
Ensembl ID
ENSG00000159788
ENSG00000146281
Uniprot IDs
O14924
Q8IYS1
PDB IDs
2EBZ
2KV8
7YH4
8XZC
Enriched GO Terms of Interacting Partners
?
Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway
Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway
G Protein-coupled Receptor Signaling Pathway
Modulation Of Chemical Synaptic Transmission
Negative Regulation Of Adenylate Cyclase Activity
Guanyl Nucleotide Binding
Signal Transduction
G-protein Beta/gamma-subunit Complex Binding
Heterotrimeric G-protein Complex
Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway
Negative Regulation Of Synaptic Transmission
GTPase Activity
Regulation Of Secretion By Cell
Negative Regulation Of Catalytic Activity
Glutamate Receptor Signaling Pathway
Regulation Of Secretion
GTP Binding
Phosphatidylinositol Phospholipase C Activity
G Protein-coupled Receptor Activity
Adenylate Cyclase-inhibiting G Protein-coupled Glutamate Receptor Signaling Pathway
Regulation Of Intracellular Signal Transduction
Regulation Of Synaptic Plasticity
Regulation Of Biological Quality
G Protein-coupled Receptor Binding
Regulation Of Synaptic Transmission, Glutamatergic
Membrane
GDP Binding
Glutamate Receptor Activity
Astrocyte Projection
Phospholipase C Activity
Regulation Of Cell Communication
Regulation Of Signaling
Calcium Ion Transmembrane Import Into Cytosol
Nucleotide Binding
G Protein-coupled Glutamate Receptor Signaling Pathway
Intracellular Signal Transduction
Schwann Cell Development
Regulation Of Catalytic Activity
Glutamatergic Synapse
G Protein-coupled Serotonin Receptor Signaling Pathway
G Protein-coupled Acetylcholine Receptor Signaling Pathway
Ciliary Basal Body
Cell-cell Signaling
Regulation Of Dopamine Secretion
Phosphatidylinositol-mediated Signaling
Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity
Signaling
Cell Surface Receptor Signaling Pathway
Regulation Of Long-term Neuronal Synaptic Plasticity
Synaptic Signaling
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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