RDX and VWA5A

		RDX	VWA5A
Description		radixin	von Willebrand factor A domain containing 5A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Ruffle Extracellular Space Cytoplasm Cytoskeleton Plasma Membrane Microvillus Adherens Junction Focal Adhesion Membrane Apical Plasma Membrane Lamellipodium Filopodium T-tubule Midbody Cortical Actin Cytoskeleton Cleavage Furrow Stereocilium Cell Projection Apical Part Of Cell Cell Tip Extracellular Exosome Cell Periphery Stereocilium Base	Nucleoplasm
	Molecular Function	RNA Binding Actin Binding Protein Binding Cytoskeletal Protein Binding Protein Domain Specific Binding Cadherin Binding Cell Adhesion Molecule Binding Protein Kinase A Binding ATPase Binding	Protein Binding
	Biological Process	Regulation Of Cell Shape Positive Regulation Of Gene Expression Protein Kinase A Signaling Microvillus Assembly Regulation Of Rap Protein Signal Transduction Cellular Response To Platelet-derived Growth Factor Stimulus Apical Protein Localization Establishment Of Protein Localization Positive Regulation Of Protein Catabolic Process Barbed-end Actin Filament Capping Actin Filament Capping Establishment Of Endothelial Barrier Establishment Of Protein Localization To Plasma Membrane Protein Localization To Plasma Membrane Cellular Response To Thyroid Hormone Stimulus Regulation Of Postsynaptic Neurotransmitter Receptor Diffusion Trapping Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Organelle Assembly Positive Regulation Of Protein Localization To Early Endosome Regulation Of Adherens Junction Organization Positive Regulation Of Early Endosome To Late Endosome Transport
Pathways		Recycling pathway of L1 Recycling pathway of L1 Sensory processing of sound by inner hair cells of the cochlea Sensory processing of sound by outer hair cells of the cochlea
Drugs		1D-myo-inositol 1,4,5-trisphosphate
Diseases
GWAS		Cognitive function ( 24684796) Computer vision syndrome ( 33941792) Coronary artery disease ( 32469254) Multiple sclerosis ( 31604244)	Aging (time to death) ( 21782286)
Interacting Genes		23 interacting genes: ABCC2 ARHGDIA C1QTNF9 CALM1 CPNE1 CPNE2 CPNE4 DRD3 EZR FTCD GNA13 ICAM2 ITGB2 L1CAM LINC01554 NHERF1 NHERF2 PRPF38A PSME3 RBPMS ROCK1 TSC1 VPS11	6 interacting genes: APP MEOX2 PPARA PRTFDC1 RHOU SPSB1
Entrez ID		5962	4013
HPRD ID		01534	04238
Ensembl ID		ENSG00000137710	ENSG00000110002
Uniprot IDs		B0YJ88 P35241 Q6PKD3	O00534
PDB IDs
Enriched GO Terms of Interacting Partners?		Type 2 Metabotropic Glutamate Receptor Binding Membrane Docking Type 3 Metabotropic Glutamate Receptor Binding Membrane To Membrane Docking Response To Calcium Ion Phospholipase C-activating Dopamine Receptor Signaling Pathway Regulation Of Cell Shape Leukocyte Cell-cell Adhesion Protein Localization To Membrane Microvillus Organization Positive Regulation Of Early Endosome To Late Endosome Transport Microvillus Assembly Calcium-dependent Phospholipid Binding Plasma Membrane Response To Metal Ion Adenylate Cyclase-activating Dopamine Receptor Signaling Pathway Rho Protein Signal Transduction Microvillus Receptor Internalization Uropod Protein Localization To Plasma Membrane Cellular Response To Calcium Ion Regulation Of Intracellular Signal Transduction Establishment Of Epithelial Cell Apical/basal Polarity Protein Localization To Cell Periphery Regulation Of Early Endosome To Late Endosome Transport Focal Adhesion Extracellular Exosome Associative Learning Cell Periphery Regulation Of Cell Morphogenesis G Protein-coupled Dopamine Receptor Signaling Pathway Cell-matrix Adhesion Ruffle Establishment Of Apical/basal Cell Polarity Polarized Epithelial Cell Differentiation Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Negative Regulation Of Intracellular Signal Transduction Cell-cell Adhesion Acid Secretion Microvillus Membrane Gland Morphogenesis Establishment Of Epithelial Cell Polarity Localization Within Membrane Positive Regulation Of Focal Adhesion Assembly Cortical Actin Cytoskeleton Organization Monocarboxylic Acid Transport Regulation Of Vesicle-mediated Transport Protein-membrane Adaptor Activity	Regulation Of Neuronal Synaptic Plasticity Visual Behavior Visual Learning Circadian Regulation Of Gene Expression Associative Learning Circadian Rhythm Adult Behavior Positive Regulation Of Long-term Synaptic Potentiation Learning Regulation Of Neurotransmitter Uptake Negative Regulation Of MiRNA Transcription Regulation Of Long-term Neuronal Synaptic Plasticity Positive Regulation Of Receptor Internalization Lipoprotein Metabolic Process Regulation Of Synaptic Plasticity Positive Regulation Of ATP Metabolic Process Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of G Protein-coupled Receptor Signaling Pathway Regulation Of Long-term Synaptic Potentiation Rhythmic Process Negative Regulation Of Blood Pressure Positive Regulation Of Gene Expression, Epigenetic Learning Or Memory Regulation Of Glycolytic Process Cellular Response To Growth Factor Stimulus Positive Regulation Of Receptor-mediated Endocytosis Amyloid-beta Complex Regulation Of Cellular Component Organization Growth Cone Lamellipodium Cognition Response To Metal Ion Response To Light Stimulus Regulation Of Response To Calcium Ion Regulation Of Developmental Growth Regulation Of Carbohydrate Catabolic Process Regulation Of Multicellular Organism Growth Response To Growth Factor Amylin Binding Positive Regulation Of Toll Signaling Pathway Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Cell Cycle Positive Regulation Of Transformation Of Host Cell By Virus Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of ATP Metabolic Process Regulation Of Biological Quality Regulation Of Receptor Internalization Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of MiRNA Transcription Positive Regulation Of RNA Biosynthetic Process Adult Locomotory Behavior
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