OPN1LW and PIAS3

Number of citations of the paper that reports this interaction (PMID 14691252)
24

Data Source:
HPRD (in vivo, in vitro)

		OPN1LW	PIAS3
Gene Name		opsin 1 (cone pigments), long-wave-sensitive	protein inhibitor of activated STAT, 3
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Photoreceptor Outer Segment Membrane	Nucleus Cytoplasm Dendrite Synapse
	Molecular Function	G-protein Coupled Receptor Activity Photoreceptor Activity	Protein Binding Protein C-terminus Binding Zinc Ion Binding Potassium Channel Regulator Activity Ligase Activity SUMO Transferase Activity Enzyme Binding Protein N-terminus Binding
	Biological Process	Retinoid Metabolic Process Signal Transduction G-protein Coupled Receptor Signaling Pathway Visual Perception Phototransduction, Visible Light Protein-chromophore Linkage Positive Regulation Of Cytokinesis	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Response To Hormone Positive Regulation Of Gene Expression Protein Sumoylation Positive Regulation Of Protein Sumoylation Positive Regulation Of Membrane Potential
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		4 interactors: NCOA2 PIAS3 RANBP2 TICAM2	49 interactors: AR ATF7IP C19orf60 CARHSP1 CBS CREM EP300 ESR1 ESR2 GEMIN4 GFI1 GLUL HABP4 HDAC1 HMGA2 MITF NCOA2 NR3C2 OPN1LW PGR PPP1CA PRPF40A PSMC1 RAC1 RELA SATB1 SERBP1 SERPINA10 SIAH1 SIAH2 SKIL SMAD2 SMAD3 SMAD4 SREBF2 STAT3 SUMO1 SUMO2 SUMO3 TBP TRIM27 TRIM32 TRIM55 TRIM63 UBA1 UBE2I ZFHX3 ZMIZ1 ZMIZ2
Entrez ID		5956	10401
HPRD ID		02366	09068
Ensembl ID		ENSG00000102076	ENSG00000131788
Uniprot IDs			B3KNI3 Q6IAR4 Q9Y6X2
PDB IDs
Enriched GO Terms of Interacting Partners?		Peptidyl-lysine Modification Protein Sumoylation Regulation Of Glucose Metabolic Process Response To Organic Substance Positive Regulation Of Interleukin-18-mediated Signaling Pathway Regulation Of Carbohydrate Metabolic Process Peptidyl-amino Acid Modification Negative Regulation Of Chemokine (C-C Motif) Ligand 5 Production Positive Regulation Of Chemokine (C-C Motif) Ligand 5 Production TRAM-dependent Toll-like Receptor 4 Signaling Pathway Regulation Of Gluconeogenesis Involved In Cellular Glucose Homeostasis Response To Interleukin-12 Positive Regulation Of Toll-like Receptor 4 Signaling Pathway Negative Regulation Of Glucokinase Activity Negative Regulation Of Toll-like Receptor 4 Signaling Pathway Cellular Response To Organic Substance Positive Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Protein Sumoylation Regulation Of Protein Sumoylation RNA Biosynthetic Process Protein Modification By Small Protein Conjugation Negative Regulation Of Toll-like Receptor Signaling Pathway Positive Regulation Of Cytokine-mediated Signaling Pathway Positive Regulation Of Response To Cytokine Stimulus Response To Cytokine Mitotic Nuclear Envelope Disassembly Regulation Of Toll-like Receptor Signaling Pathway Nuclear Envelope Disassembly Positive Regulation Of Receptor Activity Positive Regulation Of Membrane Potential Positive Regulation Of Chemokine Production Regulation Of Gluconeogenesis Positive Regulation Of Interferon-gamma Production RNA Metabolic Process Cellular Protein Modification Process Response To Hormone Regulation Of Chemokine Production I-kappaB Kinase/NF-kappaB Signaling TRIF-dependent Toll-like Receptor Signaling Pathway Gene Expression MyD88-independent Toll-like Receptor Signaling Pathway Nuclear Envelope Organization Toll-like Receptor 3 Signaling Pathway Positive Regulation Of Interleukin-6 Production Glucose Transport	Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Negative Regulation Of Cellular Metabolic Process Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Metabolic Process Gene Expression Transcription Initiation From RNA Polymerase II Promoter RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process DNA-templated Transcription, Initiation Regulation Of Transcription, DNA-templated Positive Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Biosynthetic Process Cellular Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Response To Organic Substance Regulation Of Cellular Process Macromolecule Biosynthetic Process Positive Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Viral Process Cellular Response To Organic Substance Biosynthetic Process Epithelium Development Regulation Of Signal Transduction Regulation Of Cell Death Regulation Of Signaling Response To Stimulus Cellular Response To Stimulus
Tagcloud ?			achieved atm atr consistently crucial dbc1 deficient diverse establish etoposide finely genotoxic interaction knockdown metabolism modification modifier promoted promotion remarkably senp1 sirt1 sumo sumo1 sumo2 sumoylation switching transactivation ubiquitin
Tagcloud (Difference) ?			achieved atm atr consistently crucial dbc1 deficient diverse establish etoposide finely genotoxic interaction knockdown metabolism modification modifier promoted promotion remarkably senp1 sirt1 sumo sumo1 sumo2 sumoylation switching transactivation ubiquitin
Tagcloud (Intersection) ?