RBMS1 and TFCP2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		RBMS1	TFCP2
Description		RNA binding motif single stranded interacting protein 1	transcription factor CP2
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytosol Ribonucleoprotein Complex	Chromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex
	Molecular Function	Nucleic Acid Binding DNA Binding Double-stranded DNA Binding Single-stranded DNA Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Poly(A) Binding Poly(U) RNA Binding	Transcription Cis-regulatory Region Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Transcription Factor Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	DNA Replication RNA Processing	Regulation Of Transcription By RNA Polymerase II MRNA Transcription By RNA Polymerase II Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Adult body size ( 32376654) Age at first sexual intercourse ( 34211149) Amyotrophic lateral sclerosis ( 19451621) Basal cell carcinoma ( 31174203) Body size at age 10 ( 32376654) Chronotype ( 30696823) FEV1 ( 30804560) Gut microbiota relative abundance (Ruminococcus belonging to family Lachnospiraceae) ( 33208821) HDL cholesterol levels ( 32203549) High light scatter reticulocyte count ( 32888494) High light scatter reticulocyte percentage of red cells ( 32888494) Hip circumference adjusted for BMI ( 34021172) Idiopathic membranous nephropathy ( 21323541) Intelligence (MTAG) ( 29326435) Lung function (FVC) ( 30804560) Lymphocyte count ( 27863252 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Monocyte percentage of white cells ( 27863252 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 32888494) Peak expiratory flow ( 30804560) Refractive error ( 32231278) Reticulocyte count ( 32888494) Reticulocyte fraction of red cells ( 32888494) Systolic blood pressure ( 30224653) Tourette syndrome ( 30818990) Triglyceride levels ( 32203549) Type 2 diabetes ( 20418489 30297969 30054458 29358691 22885922) Waist circumference adjusted for body mass index ( 34021172) Weight ( 31647587 28552196) White blood cell count ( 32888494 27863252)
Interacting Genes		10 interacting genes: MIR16-2 MIR205 MIR29A MIR7-1 MIR92A2 MIR93 MIRLET7G OGT POLA1 TFCP2	73 interacting genes: ACAA1 ADPRH APBB1 ASAP3 BAG6 C19orf73 CA1 CAPN3 CASP8 CBX8 CDC73 COIL DNAJC5B DPH1 E2F8 EAF1 EIF5B EPHA10 FAM120C FANCL FARS2 FBXL18 FXR2 GPANK1 HAPLN2 HDAC1 HDAC2 IRAK1BP1 LDB3 LSM1 MAPK1 MAPK14 MAPK8 MOB3C MORF4L1 MRPL11 MRPL40 MVP NABP1 NEDD9 NFE4 NHSL2 NOM1 NPEPL1 PHF1 PHF21B PIMREG PITPNM1 PLCB1 POLL POLR3GL PPIG PPP1R1B PPP3R2 PSMD5 RBMS1 RNF2 RXRB SDCBP SHTN1 SIN3A STMN2 SUMO1 TCEA2 TDRD1 TLK1 TRAPPC12 TSPAN12 UBE2I YJU2 YY1 ZCCHC10 ZCCHC12
Entrez ID		5937	7024
HPRD ID		03814	01790
Ensembl ID		ENSG00000153250	ENSG00000135457
Uniprot IDs		A0A0S2Z499 P29558	Q12800
PDB IDs		1X5O 6M75 7C36
Enriched GO Terms of Interacting Partners?		RISC Complex MiRNA-mediated Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Regulatory NcRNA-mediated Gene Silencing Post-transcriptional Regulation Of Gene Expression Negative Regulation Of Gene Expression MRNA Base-pairing Post-transcriptional Repressor Activity Negative Regulation Of Cell Migration Negative Regulation Of Cell Motility Negative Regulation Of Locomotion Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Gene Expression Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of Vascular Endothelial Growth Factor Production MRNA 3'-UTR Binding Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Cell Migration Negative Regulation Of SMAD Protein Signal Transduction Negative Regulation Of Translation Regulation Of Cell Motility Regulation Of Locomotion Regulation Of Vascular Endothelial Growth Factor Production MiRNA-mediated Gene Silencing By Inhibition Of Translation Protein N-acetylglucosaminyltransferase Complex Negative Regulation Of Non-canonical Inflammasome Complex Assembly Cellular Response To Glucose Stimulus Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Signal Transduction Regulation Of SMAD Protein Signal Transduction Regulation Of Angiogenesis Regulation Of Vasculature Development Regulation Of Cellular Response To Growth Factor Stimulus Cellular Response To Carbohydrate Stimulus Extracellular Space Negative Regulation Of Cell Communication Negative Regulation Of Signaling Intracellular Glucose Homeostasis Extracellular Vesicle Negative Regulation Of Developmental Process Regulation Of Translation Lagging Strand Elongation	Nucleus Sin3-type Complex Protein Binding Nucleoplasm DNA Damage Response MAP Kinase Activity Protein Lysine Delactylase Activity Fungiform Papilla Formation RING-like Zinc Finger Domain Binding Macromolecule Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Stress-activated MAPK Cascade Chromatin Binding Chromatin Organization Stress-activated Protein Kinase Signaling Cascade Hair Follicle Placode Formation Negative Regulation Of Stem Cell Population Maintenance PcG Protein Complex Small Protein Activating Enzyme Binding Postsynaptic Cytosol Cellular Response To Stress Enzyme Binding Cellular Response To Dopamine Response To Dopamine Nucleic Acid Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Metabolic Process Self Proteolysis Fibroblast Proliferation Histone Deacetylase Complex Histone Deacetylase Activity, Hydrolytic Mechanism Substrate-dependent Cell Migration, Cell Extension Negative Regulation Of Gene Expression, Epigenetic
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