RBBP8 and LMO1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		RBBP8	LMO1
Gene Name		retinoblastoma binding protein 8	LIM domain only 1 (rhombotin 1)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Transcriptional Repressor Complex	Nucleus
	Molecular Function	Single-stranded DNA Endodeoxyribonuclease Activity RNA Polymerase II Repressing Transcription Factor Binding RNA Polymerase II Transcription Corepressor Activity Damaged DNA Binding Protein Binding	Zinc Ion Binding
	Biological Process	Cell Cycle Checkpoint G1/S Transition Of Mitotic Cell Cycle Negative Regulation Of Transcription From RNA Polymerase II Promoter Double-strand Break Repair Via Homologous Recombination DNA Catabolic Process, Endonucleolytic Blastocyst Hatching DNA Repair Regulation Of Transcription From RNA Polymerase II Promoter Mitotic Nuclear Division DNA Double-strand Break Processing Involved In Repair Via Single-strand Annealing G2 DNA Damage Checkpoint Cell Division Meiotic Cell Cycle	Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Meiotic recombination
Drugs
Diseases
GWAS		Height ( 18391951) Intracranial aneurysm ( 20364137) Tuberculosis ( 20694014)	Alcohol consumption ( 23743675) Fasting glucose-related traits (interaction with BMI) ( 22581228) Neuroblastoma ( 22941191 21124317)
Protein-Protein Interactions		34 interactors: ATM BARD1 BRCA1 CLU CTBP1 CTBP2 EEF1A1 FXR2 FZR1 HID1 IGFBP7 IKBKG IKZF1 IKZF3 LIMS1 LMO1 LMO2 LMO4 MAP2K4 MRE11A PCNA PIN1 PRKDC PRRG4 RAF1 RB1 RBL1 RBL2 RGS17 SIAH1 SIAH2 TGIF2 TMEM54 WDYHV1	38 interactors: ADAMTSL4 AES BCL11A BLZF1 CARD9 CDCA7L CDX4 CEP170P1 CEP44 ERBB2IP FAM154A FAM208B GABPB1 GATA3 GOLGA2 IKZF3 KANK2 KRT40 LDB1 LPXN LYL1 LZTS2 NHLH1 NUTM1 PHC2 PTPN3 RBBP8 REL SNTA1 SOX5 SPERT TAL1 TAL2 TCF4 TFIP11 TRIM27 ZBTB43 ZNF219
Entrez ID		5932	4004
HPRD ID		04990	01738
Ensembl ID		ENSG00000101773	ENSG00000166407
Uniprot IDs		Q99708	P25800
PDB IDs		2L4Z
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Cell Cycle Positive Regulation Of Cellular Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Gene Expression Regulation Of Cell Cycle Regulation Of Protein Metabolic Process Positive Regulation Of Cellular Biosynthetic Process G2 DNA Damage Checkpoint Negative Regulation Of Biosynthetic Process Regulation Of Cellular Protein Metabolic Process Regulation Of RNA Metabolic Process Negative Regulation Of Protein Metabolic Process Regulation Of Apoptotic Process Positive Regulation Of Protein Metabolic Process Apoptotic Process Regulation Of Cell Death Cell Cycle Checkpoint Regulation Of Nucleic Acid-templated Transcription Programmed Cell Death Regulation Of RNA Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Phosphorylation Cell Death Negative Regulation Of Gene Expression Death Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Catalytic Activity Nucleobase-containing Compound Metabolic Process Positive Regulation Of Cellular Protein Metabolic Process DNA Damage Checkpoint Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Cellular Process Positive Regulation Of Protein Modification Process Telomere Maintenance Regulation Of Phosphorus Metabolic Process Response To Organic Substance Immune System Process Heterocycle Metabolic Process Regulation Of Transcription, DNA-templated Cellular Aromatic Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Cycle Process Positive Regulation Of Gene Expression Double-strand Break Repair Via Homologous Recombination Recombinational Repair	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Metabolic Process Negative Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Cellular Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Wnt Signaling Pathway Organ Development Positive Regulation Of Cellular Metabolic Process Interferon-gamma Secretion Multicellular Organismal Development Cellular Metabolic Process Anatomical Structure Development Developmental Process System Development Interferon-gamma Production Negative Regulation Of Interleukin-2 Production Regulation Of Binding Negative Regulation Of Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Cytokine Biosynthetic Process Definitive Hemopoiesis Embryo Development
Tagcloud ?		advance breaks cluster ctip doi downregulates downregulating dsbs elusive faithful genotoxic hypersensitivity impairs mechanistic microrna mir october onc oncogenic oncomir online polycistronic publication recombination repressed resection strand suppresses untranslated	bhlh collaborates collaboration construct demonstrating dispensable dysregulation elements exerts helix inappropriately interfere interstitial juxtaposed lastly lymphoblastic mesoderm misexpressed oncogenesis product recapitulating scl sil situation supporting tcl5 transactivation translocations whereby
Tagcloud (Difference) ?		advance breaks cluster ctip doi downregulates downregulating dsbs elusive faithful genotoxic hypersensitivity impairs mechanistic microrna mir october onc oncogenic oncomir online polycistronic publication recombination repressed resection strand suppresses untranslated	bhlh collaborates collaboration construct demonstrating dispensable dysregulation elements exerts helix inappropriately interfere interstitial juxtaposed lastly lymphoblastic mesoderm misexpressed oncogenesis product recapitulating scl sil situation supporting tcl5 transactivation translocations whereby
Tagcloud (Intersection) ?