RAB3A and SYTL5

Number of citations of the paper that reports this interaction (PubMedID 12051743)
0

Data Source:
HPRD (in vitro, in vivo)

		RAB3A	SYTL5
Description		RAB3A, member RAS oncogene family	synaptotagmin like 5
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Acrosomal Vesicle Cytoplasm Lysosome Endosome Cytosol Plasma Membrane Synaptic Vesicle Membrane Transport Vesicle Axon Secretory Granule Membrane Synaptic Vesicle Membrane Cytoplasmic Vesicle Vesicle Cell Projection Terminal Bouton Synapse Perinuclear Region Of Cytoplasm Presynaptic Active Zone Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Clathrin-sculpted Glutamate Transport Vesicle Membrane Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Clathrin-sculpted Monoamine Transport Vesicle Membrane Presynapse Postsynapse Extracellular Vesicle	Plasma Membrane Membrane Exocytic Vesicle
	Molecular Function	Nucleotide Binding GTPase Activity Protein Binding GTP Binding Hydrolase Activity Protein-macromolecule Adaptor Activity GTP-dependent Protein Binding Myosin V Binding Metal Ion Binding	Protein Binding Phospholipid Binding Zinc Ion Binding Small GTPase Binding Neurexin Family Protein Binding Metal Ion Binding
	Biological Process	Plasma Membrane Repair Respiratory System Process Exocytosis Mitochondrion Organization Neuromuscular Synaptic Transmission Axonogenesis Post-embryonic Development Protein Transport Synaptic Vesicle Exocytosis Synaptic Vesicle Maturation Calcium-ion Regulated Exocytosis Regulation Of Exocytosis Insulin Secretion Lung Development Regulation Of Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Lysosome Localization Synaptic Vesicle Recycling Constitutive Secretory Pathway Regulated Exocytosis Positive Regulation Of Exocytosis Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Transport Maintenance Of Presynaptic Active Zone Structure Sensory Perception Of Touch Response To Electrical Stimulus Establishment Of Localization In Cell Acrosomal Vesicle Exocytosis Evoked Neurotransmitter Secretion Synaptic Vesicle Clustering Regulation Of Presynaptic Dense Core Granule Exocytosis Positive Regulation Of Regulated Secretory Pathway Regulation Of Plasma Membrane Repair	Intracellular Protein Transport Exocytosis
Pathways		Serotonin Neurotransmitter Release Cycle Norepinephrine Neurotransmitter Release Cycle Glutamate Neurotransmitter Release Cycle Dopamine Neurotransmitter Release Cycle Acetylcholine Neurotransmitter Release Cycle Neutrophil degranulation RAB geranylgeranylation RAB GEFs exchange GTP for GDP on RABs GABA synthesis, release, reuptake and degradation Sensory processing of sound by inner hair cells of the cochlea
Drugs
Diseases
GWAS		Emphysema annual change measurement in smokers (percent low attenuation area) ( 31324189)	Anorexia nervosa ( 23568457) Erectile dysfunction and prostate cancer treatment ( 20932654)
Interacting Genes		32 interacting genes: A2M ADRB2 AP1M2 APP CASK CHM CHML CHRM4 DMXL2 ECSIT EGFR GRSF1 KRTAP10-8 MAST1 MYO5A PSEN1 RAB3IL1 RAB3IP RABAC1 RABGGTB RABIF REP15 RIMS1 RIMS2 RNF32 RPH3A RPH3AL SGSM2 SNCA SYTL4 SYTL5 VRTN	8 interacting genes: CCDC85A CEP70 RAB27A RAB3A RAB6A TRIM54 WAC YIF1A
Entrez ID		5864	94122
HPRD ID		01535	06736
Ensembl ID		ENSG00000105649	ENSG00000147041
Uniprot IDs		A0A024R7I7 P20336	Q8TDW5
PDB IDs
Enriched GO Terms of Interacting Partners?		Small GTPase Binding Vesicle-mediated Transport Cellular Localization Establishment Of Localization In Cell Protein Transport Establishment Of Protein Localization Intracellular Transport Intracellular Protein Localization Rab-protein Geranylgeranyltransferase Complex Synaptic Vesicle Priming Regulation Of Exocytosis Protein Geranylgeranylation Positive Regulation Of Excitatory Postsynaptic Potential Regulation Of Vesicle-mediated Transport Synapse Intracellular Protein Transport Protein Prenylation Secretion By Cell Neurexin Family Protein Binding Exocytosis Modulation Of Excitatory Postsynaptic Potential Cytoplasmic Vesicle Secretion Regulation Of Regulated Secretory Pathway Synaptic Vesicle Positive Regulation Of Vesicle Fusion Neuronal Dense Core Vesicle Signal Release Positive Regulation Of Exocytosis Astrocyte Activation Involved In Immune Response Rab Geranylgeranyltransferase Activity Regulation Of Neurotransmitter Secretion Modulation Of Chemical Synaptic Transmission Positive Regulation Of Amyloid Fibril Formation Growth Factor Receptor Binding Neurotransmitter Transport Synaptic Vesicle Exocytosis Regulation Of Vesicle Fusion Spontaneous Neurotransmitter Secretion Positive Regulation Of Inhibitory Postsynaptic Potential Neurotransmitter Secretion Regulation Of Nervous System Process Regulation Of Secretion By Cell Structural Constituent Of Presynaptic Active Zone Modulation Of Inhibitory Postsynaptic Potential Maintenance Of Presynaptic Active Zone Structure Synapse Organization Regulation Of Synaptic Vesicle Exocytosis Presynaptic Membrane Cellular Response To Amyloid-beta	Myosin V Binding Regulation Of Presynaptic Dense Core Granule Exocytosis Positive Regulation Of Regulated Secretory Pathway GTPase Activity Synaptic Vesicle Transport GTP Binding Establishment Of Organelle Localization Evoked Neurotransmitter Secretion Peptidyl-cysteine Methylation Cytotoxic T Cell Degranulation Positive Regulation Of Constitutive Secretory Pathway Protein Localization To Extracellular Region Organelle Localization Clathrin-sculpted Acetylcholine Transport Vesicle Membrane Vesicle-mediated Transport Regulated Exocytosis Positive Regulation Of Exocytosis Protein Transport Establishment Of Protein Localization To Extracellular Region Protein Secretion Vesicle Localization Regulation Of Dense Core Granule Exocytosis Secretory Granule Membrane Sensory Perception Of Touch Establishment Of Vesicle Localization Antigen Processing And Presentation Endosome To Plasma Membrane Transport Vesicle Complement-dependent Cytotoxicity Regulation Of Regulated Secretory Pathway Establishment Of Protein Localization Clathrin-sculpted Glutamate Transport Vesicle Membrane Minus-end-directed Organelle Transport Along Microtubule Exosomal Secretion Acrosomal Vesicle Exocytosis Clathrin-sculpted Monoamine Transport Vesicle Membrane Regulation Of Microtubule Cytoskeleton Organization Constitutive Secretory Pathway Protein Localization To Golgi Membrane Weibel-Palade Body Regulation Of Exocytosis Regulation Of Plasma Membrane Repair Regulation Of Calcium Ion-dependent Exocytosis Of Neurotransmitter Natural Killer Cell Degranulation Establishment Of Localization In Cell Synaptic Vesicle Maturation Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane Maintenance Of Presynaptic Active Zone Structure Exocytosis Presynaptic Active Zone Organization Protein Domain Specific Binding
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