TMEM132D and TUBGCP5

Number of citations of the paper that reports this interaction (PubMedID 33726789)
50

Data Source:
BioGRID (two hybrid)

		TMEM132D	TUBGCP5
Description		transmembrane protein 132D	tubulin gamma complex component 5
Image		No pdb structure
GO Annotations	Cellular Component	Membrane	Spindle Pole Gamma-tubulin Complex Gamma-tubulin Ring Complex Cytoplasm Centrosome Microtubule Organizing Center Cytosol Cytoskeleton Microtubule Cilium Ciliary Basal Body
	Molecular Function	Protein Binding	Protein Binding Microtubule Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process		Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle
Pathways			Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
Drugs
Diseases
GWAS		Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL) ( 28090653) Anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anti-thyroid peroxidase (TPOAb) and anti-thyroglobulin (TgAb) levels in Hashimoto's thyroiditis ( 30926877) Anxiety disorder ( 25390645) Asthma ( 29273806) Blood protein levels ( 30072576) Body fat mass ( 28552196) Cognitive decline rate in late mild cognitive impairment ( 26252872) Heart rate ( 23534349) Initial pursuit acceleration ( 29064472) Male-pattern baldness ( 27182965) Mosquito bite size ( 28199695) Obesity-related traits ( 23251661) Positive urgency ( 30718321) Retinal venular tortuosity ( 31597446) Schizophrenia (inflammation and infection response interaction) ( 25781172) Sleep (1/2-day periodicity) ( 33075057) Triglyceride levels ( 34074324) Trunk fat mass ( 28552196) Type 2 diabetes (age of onset) ( 28060188)	Bipolar disorder ( 34099189) Obsessive-compulsive disorder ( 30456828) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		70 interacting genes: ANKRD31 ANKRD36 ARL3 ATP1B1 ATP7A BNIP3L CADPS2 CCDC85A CD59 CMPK1 CNGB3 CNTN1 COMMD1 COX11 CPD EFEMP1 ENOPH1 FAM106A FMO2 GFM2 H3C1 HDAC2 HEBP2 HNRNPUL1 HOXA9 IDI2-AS1 IL13RA1 LNX1 MIR181A1HG MME NAMPT NCKAP1 NDUFS5 NPAS3 PAIP1 PCCA PCLO PGM1 PLSCR2 PNISR PRMT3 PRPF40A PTPN2 PTPRD RAB6A RCBTB2 RNF2 SAMD12 SDHB SEC22B SHLD2 SLC35E2A SRSF5 STK39 SVIL TCF12 TMED5 TMED7-TICAM2 TNFAIP8 TOB2 TPST1 TRAPPC11 TRAPPC8 TUBGCP5 UBA5 UMOD USP32P2 VPS13C ZBTB20 ZNF302	4 interacting genes: CLIC6 CRYAA HEMK1 TMEM132D
Entrez ID		121256	114791
HPRD ID		13906	12177
Ensembl ID		ENSG00000151952	ENSG00000275835
Uniprot IDs		Q14C87	Q96RT8
PDB IDs			6L81 6V69 6V6S 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 7QJE 8Q62 8RX1 8VRD 8VRJ 8VRK
Enriched GO Terms of Interacting Partners?		Golgi Vesicle Transport Protein Transport Into Plasma Membrane Raft Purine Nucleotide Metabolic Process Nucleotide Metabolic Process Ribonucleotide Metabolic Process Ribose Phosphate Metabolic Process ATP Metabolic Process Nucleoside Phosphate Metabolic Process Protein Transport Into Membrane Raft Positive Regulation Of Potassium Ion Import Across Plasma Membrane Purine Ribonucleotide Metabolic Process Nucleobase-containing Small Molecule Metabolic Process Protein Localization To Plasma Membrane Raft Purine-containing Compound Metabolic Process Regulation Of Sodium Ion Transport Regulation Of Potassium Ion Import Positive Regulation Of Sodium Ion Transport	Protein-glutamine N-methyltransferase Activity Peptide Chain Release Factor N(5)-glutamine Methyltransferase Activity D4 Dopamine Receptor Binding D3 Dopamine Receptor Binding D2 Dopamine Receptor Binding N-methyltransferase Activity Lens Fiber Cell Morphogenesis Tubulin Complex Assembly Response To UV-A Embryonic Camera-type Eye Morphogenesis Lens Morphogenesis In Camera-type Eye Protein Methyltransferase Activity Translational Termination
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