BBS2 and FHOD1

Number of citations of the paper that reports this interaction (PMID 18000879)
5

Data Source:
BioGRID (two hybrid)

		BBS2	FHOD1
Gene Name		Bardet-Biedl syndrome 2	formin homology 2 domain containing 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Motile Cilium BBSome Ciliary Basal Body Ciliary Membrane	Stress Fiber Nucleus Cytoplasm Membrane Bleb
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	Actin Binding Protein Binding Identical Protein Binding
	Biological Process	Organelle Organization Sperm Axoneme Assembly Visual Perception Protein Localization Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Nonmotile Primary Cilium Assembly Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Morphogenesis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility	Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Stress Fiber Assembly
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 HSCB KRT18 MDFI PAX2 PSME3 RBPMS	20 interactors: ACTA1 ACTG1 APC BBS1 BBS2 BBS4 BBS7 CR2 EXOSC8 GRB2 LNPEP NCOA6 PFN2 PPARG PRKG1 RAC1 RANBP2 RNF5 YWHAZ ZMYND8
Entrez ID		583	29109
HPRD ID		05855	06049
Ensembl ID		ENSG00000125124	ENSG00000135723
Uniprot IDs		Q9BXC9	Q9Y613
PDB IDs			3DAD
Enriched GO Terms of Interacting Partners?		Cellular Response To Epidermal Growth Factor Stimulus Response To Epidermal Growth Factor Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Optic Chiasma Development Positive Regulation Of Optic Nerve Formation Golgi To Plasma Membrane CFTR Protein Transport Pronephric Field Specification Optic Nerve Structural Organization Negative Regulation Of Apoptotic Process Involved In Metanephric Collecting Duct Development Negative Regulation Of Apoptotic Process Involved In Metanephric Nephron Tubule Development Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephric Nephron Morphogenesis Positive Regulation Of Metanephric DCT Cell Differentiation Regulation Of Metanephros Size S-methylmethionine Cycle S-methylmethionine Metabolic Process Embryonic Organ Development Embryonic Placenta Development Amino-acid Betaine Catabolic Process Regulation Of Homocysteine Metabolic Process Negative Regulation Of Cytolysis Kidney Rudiment Formation Paramesonephric Duct Development Vestibulocochlear Nerve Formation Metanephric Nephron Tubule Formation Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Nephron Morphogenesis Regulation Of Kidney Size Positive Regulation Of Metabolic Process Positive Regulation Of Metanephric Glomerulus Development Nephric Duct Formation Metanephric Mesenchymal Cell Differentiation Ureter Morphogenesis Metanephric Tubule Formation Ureter Maturation Regulation Of Protein Import Into Nucleus Visual Perception Sensory Perception Of Light Stimulus Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Mesodermal Cell Fate Specification Myoblast Fate Commitment Placenta Development Negative Regulation Of Wnt Signaling Pathway Metanephric Distal Convoluted Tubule Development Metanephric Nephron Tubule Morphogenesis Regulation Of Protein Localization To Nucleus Cellular Response To Oxidative Stress Cellular Response To Stress Developmental Process Involved In Reproduction Optic Cup Morphogenesis Involved In Camera-type Eye Development	Nonmotile Primary Cilium Assembly Cell Projection Organization Retina Homeostasis Cell Projection Morphogenesis Cell Part Morphogenesis Tissue Homeostasis Positive Regulation Of Organelle Organization Cellular Component Assembly Cell Morphogenesis Organelle Organization Multicellular Organismal Homeostasis Organelle Assembly Cytoskeleton Organization Cellular Response To Stimulus Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Positive Regulation Of Protein Polymerization Regulation Of Cell Projection Assembly Photoreceptor Cell Maintenance Cell Differentiation Cell Projection Assembly Fat Cell Differentiation Melanosome Transport Pigment Granule Transport Membrane Organization Establishment Of Melanosome Localization Response To Stimulus Positive Regulation Of Cellular Component Biogenesis Nervous System Development Regulation Of Organelle Organization Melanosome Localization Signal Transduction Cell Development Organ Development Homeostatic Process Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Cell Surface Receptor Signaling Pathway Positive Regulation Of Protein Complex Assembly Cilium Assembly Visual Perception Sensory Perception Of Light Stimulus Anatomical Structure Formation Involved In Morphogenesis Cell Activation Signaling Cilium Organization Leptin-mediated Signaling Pathway Cell Communication Cellular Pigmentation Platelet Activation Anatomical Structure Development Blood Coagulation
Tagcloud ?		actr1a backgrounds bovines c2orf29 cnot7 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131	actin adhesions adhesive arrays assembly bilayers clusters coordinated depends find force formin impairs insights integrin integrins matrix maturation pillar polymerization question raises recruited rho sensing spreading steps substrates upstream
Tagcloud (Difference) ?		actr1a backgrounds bovines c2orf29 cnot7 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131	actin adhesions adhesive arrays assembly bilayers clusters coordinated depends find force formin impairs insights integrin integrins matrix maturation pillar polymerization question raises recruited rho sensing spreading steps substrates upstream
Tagcloud (Intersection) ?