BBS2 and FHOD1

Number of citations of the paper that reports this interaction (PubMedID 18000879)
0

Data Source:
BioGRID (two hybrid)

		BBS2	FHOD1
Description		Bardet-Biedl syndrome 2	formin homology 2 domain containing 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Cytoskeleton Plasma Membrane Microvillus Cilium Membrane Motile Cilium Stereocilium Centriolar Satellite BBSome Ciliary Basal Body Cell Projection Neuron Projection Ciliary Membrane	Stress Fiber Nucleus Nucleoplasm Cytoplasm Cytosol Cytoskeleton Intercalated Disc Membrane Bleb Cell Projection
	Molecular Function	Protein Binding RNA Polymerase II-specific DNA-binding Transcription Factor Binding	Actin Binding Protein Binding Identical Protein Binding Actin Filament Binding
	Biological Process	Sperm Axoneme Assembly Visual Perception Intracellular Protein Localization Gene Expression Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Protein Transport Striatum Development Hippocampus Development Cerebral Cortex Development Cell Projection Organization Adult Behavior Melanosome Transport Leptin-mediated Signaling Pathway Protein Localization To Organelle Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Response To Leptin Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Assembly Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Non-motile Cilium Assembly	Actin Filament Organization Nuclear Migration Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Stress Fiber Assembly Positive Regulation Of Stress Fiber Assembly Establishment Of Centrosome Localization
Pathways		BBSome-mediated cargo-targeting to cilium
Drugs
Diseases		Bardet-Biedl syndrome (BBS)
GWAS			Waist circumference adjusted for body mass index ( 34021172)
Interacting Genes		17 interacting genes: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 FNDC3B HNRNPF HSCB KRT18 LMO4 MDFI NRF1 PAX2 PJA2 PSME3 RBPMS UBC	22 interacting genes: ACTA1 ACTG1 APC BBS1 BBS2 BBS4 BBS7 CR2 EXOSC8 GRB2 LNPEP NCOA6 NLGN3 PFN2 PPARG PRKG1 RAC1 RANBP2 RNF5 TRIM21 YWHAZ ZMYND8
Entrez ID		583	29109
HPRD ID		05855	06049
Ensembl ID		ENSG00000125124	ENSG00000135723
Uniprot IDs		A0A804HIE1 A0A804HKG1 Q9BXC9	A0A068F7M9 Q9Y613
PDB IDs			3DAD 6XF1 6XF2
Enriched GO Terms of Interacting Partners?		Reverse Cholesterol Transport Very-low-density Lipoprotein Particle Remodeling Centriolar Satellite Cholesterol Transport Triglyceride-rich Lipoprotein Particle Remodeling Regulation Of Cholesterol Transport Regulation Of Primary Metabolic Process Sterol Transport Sterol Homeostasis Cholesterol Homeostasis Microtubule Organizing Center	BBSome Regulation Of Cell Motility Regulation Of Locomotion Dendrite Development Regulation Of Biological Quality Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Negative Regulation Of Immune Response Negative Regulation Of Innate Immune Response Regulation Of Microtubule-based Movement Non-motile Cilium Assembly Fat Cell Differentiation Ciliary Membrane Regulation Of Organelle Organization Regulation Of Metabolic Process Striatum Development Regulation Of Cilium Beat Frequency Positive Regulation Of Cellular Component Biogenesis Brain Morphogenesis Melanosome Transport Establishment Of Melanosome Localization Pigment Granule Transport Melanosome Localization Pigment Granule Localization Regulation Of Stress Fiber Assembly Regulation Of Supramolecular Fiber Organization Regulation Of Cell Projection Assembly Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Cytosol Regulation Of Cilium Movement Positive Regulation Of Plasma Membrane Bounded Cell Projection Assembly Regulation Of Actin Filament Organization Cytoskeleton Organization Regulation Of Microtubule-based Process Photoreceptor Cell Maintenance Regulation Of Actin Filament Polymerization Centriolar Satellite Negative Regulation Of Defense Response Neuron Migration Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Positive Regulation Of Actin Filament Polymerization Adult Behavior Cytoskeleton Regulation Of Cytoskeleton Organization Negative Regulation Of Metabolic Process Negative Regulation Of Immune System Process Negative Regulation Of Cell Migration Cellular Developmental Process Regulation Of Actin Cytoskeleton Organization Negative Regulation Of Cell Motility
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