BBS2 and HSCB

Number of citations of the paper that reports this interaction (PMID 18000879)
5

Data Source:
BioGRID (two hybrid)

		BBS2	HSCB
Gene Name		Bardet-Biedl syndrome 2	HscB mitochondrial iron-sulfur cluster co-chaperone
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol Motile Cilium BBSome Ciliary Basal Body Ciliary Membrane	Cytoplasm Mitochondrion Centrosome Plasma Membrane
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Protein Binding	Molecular_function Protein Binding Metal Ion Binding Chaperone Binding
	Biological Process	Organelle Organization Sperm Axoneme Assembly Visual Perception Protein Localization Negative Regulation Of Gene Expression Artery Smooth Muscle Contraction Striatum Development Hippocampus Development Cerebral Cortex Development Adult Behavior Melanosome Transport Protein Localization To Organelle Nonmotile Primary Cilium Assembly Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Negative Regulation Of Multicellular Organism Growth Positive Regulation Of Multicellular Organism Growth Vasodilation Golgi To Plasma Membrane Protein Transport Fat Cell Differentiation Photoreceptor Cell Maintenance Brain Morphogenesis Cartilage Development Cilium Morphogenesis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility	Protein Folding Iron-sulfur Cluster Assembly Protein Oligomerization
Pathways		Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Assembly of the primary cilium BBSome-mediated cargo-targeting to cilium	Mitochondrial protein import
Drugs
Diseases
GWAS			Esophageal cancer and gastric cancer ( 20729852)
Protein-Protein Interactions		11 interactors: BHMT EEF1A1 EPAS1 EXOC7 FHOD1 HSCB KRT18 MDFI PAX2 PSME3 RBPMS	4 interactors: AGTRAP BBS1 BBS2 BBS4
Entrez ID		583	150274
HPRD ID		05855	16289
Ensembl ID		ENSG00000125124	ENSG00000100209
Uniprot IDs		Q9BXC9	B0QYH2 Q8IWL3
PDB IDs			3BVO
Enriched GO Terms of Interacting Partners?		Cellular Response To Epidermal Growth Factor Stimulus Response To Epidermal Growth Factor Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Optic Chiasma Development Positive Regulation Of Optic Nerve Formation Golgi To Plasma Membrane CFTR Protein Transport Pronephric Field Specification Optic Nerve Structural Organization Negative Regulation Of Apoptotic Process Involved In Metanephric Collecting Duct Development Negative Regulation Of Apoptotic Process Involved In Metanephric Nephron Tubule Development Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephric Nephron Morphogenesis Positive Regulation Of Metanephric DCT Cell Differentiation Regulation Of Metanephros Size S-methylmethionine Cycle S-methylmethionine Metabolic Process Embryonic Organ Development Embryonic Placenta Development Amino-acid Betaine Catabolic Process Regulation Of Homocysteine Metabolic Process Negative Regulation Of Cytolysis Kidney Rudiment Formation Paramesonephric Duct Development Vestibulocochlear Nerve Formation Metanephric Nephron Tubule Formation Positive Regulation Of Mesenchymal To Epithelial Transition Involved In Metanephros Morphogenesis Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Nephron Morphogenesis Regulation Of Kidney Size Positive Regulation Of Metabolic Process Positive Regulation Of Metanephric Glomerulus Development Nephric Duct Formation Metanephric Mesenchymal Cell Differentiation Ureter Morphogenesis Metanephric Tubule Formation Ureter Maturation Regulation Of Protein Import Into Nucleus Visual Perception Sensory Perception Of Light Stimulus Negative Regulation Of Mesenchymal Cell Apoptotic Process Involved In Metanephros Development Mesodermal Cell Fate Specification Myoblast Fate Commitment Placenta Development Negative Regulation Of Wnt Signaling Pathway Metanephric Distal Convoluted Tubule Development Metanephric Nephron Tubule Morphogenesis Regulation Of Protein Localization To Nucleus Cellular Response To Oxidative Stress Cellular Response To Stress Developmental Process Involved In Reproduction Optic Cup Morphogenesis Involved In Camera-type Eye Development	Nonmotile Primary Cilium Assembly Photoreceptor Cell Maintenance Negative Regulation Of Appetite By Leptin-mediated Signaling Pathway Retina Homeostasis Regulation Of Cilium Beat Frequency Involved In Ciliary Motility Leptin-mediated Signaling Pathway Negative Regulation Of Appetite Cellular Response To Leptin Stimulus Cilium Assembly Visual Perception Sensory Perception Of Light Stimulus Regulation Of Microtubule-based Movement Tissue Homeostasis Cilium Organization Response To Leptin Striatum Development Cilium Morphogenesis Regulation Of Response To Food Multicellular Organismal Homeostasis Regulation Of Appetite Subpallium Development Golgi To Plasma Membrane Protein Transport Cell Projection Assembly Blood Circulation Golgi To Plasma Membrane Transport Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Brain Morphogenesis Positive Regulation Of Multicellular Organism Growth Organelle Assembly Cellular Pigmentation Protein Localization To Organelle Hippocampus Development Establishment Of Protein Localization To Plasma Membrane Post-Golgi Vesicle-mediated Transport Limbic System Development Regulation Of Multicellular Organism Growth Pigmentation Sensory Perception Fat Cell Differentiation Cell Projection Morphogenesis Cell Part Morphogenesis Spermatid Development Spermatid Differentiation Protein Localization To Plasma Membrane Positive Regulation Of Developmental Growth Cerebral Cortex Development Adult Behavior
Tagcloud ?		actr1a backgrounds bovines c2orf29 cnot7 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131	acetylserine azotobacter bear cluster cyse designated desulfurization fdx hemophilus homodimer hsca hscba influenzae isca iscs iscsua iscu microsequencing nif nifs nifu nitrogenase oligopeptides orf6 proposal pyridoxal sulfur tryptic vinelandii
Tagcloud (Difference) ?		actr1a backgrounds bovines c2orf29 cnot7 cq cycling dnajc17 endometrium establishes friesian gapdh genorm holstein normalise normalised normfinder oestrus oxtr oxytocin ppia ranbp10 rps15a rps9 slc30a6 suitability suz12 uxt znf131	acetylserine azotobacter bear cluster cyse designated desulfurization fdx hemophilus homodimer hsca hscba influenzae isca iscs iscsua iscu microsequencing nif nifs nifu nitrogenase oligopeptides orf6 proposal pyridoxal sulfur tryptic vinelandii
Tagcloud (Intersection) ?