MARK4 and MAP2

Number of citations of the paper that reports this interaction (PMID 14594945)
21

Data Source:
HPRD (in vitro)

		MARK4	MAP2
Gene Name		MAP/microtubule affinity-regulating kinase 4	microtubule-associated protein 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Microtubule Organizing Center Cytosol Microtubule Cytoskeleton Neuron Projection	Nucleolus Cytoplasm Microtubule Microtubule Associated Complex Nuclear Periphery Neuronal Cell Body Dendritic Shaft
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Gamma-tubulin Binding Ubiquitin Binding Tau-protein Kinase Activity	Dystroglycan Binding Structural Molecule Activity Protein Binding Calmodulin Binding Microtubule Binding
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Protein Phosphorylation Organelle Organization Nervous System Development Positive Regulation Of Programmed Cell Death	Microtubule Bundle Formation Axonogenesis Central Nervous System Neuron Development Neuron Projection Development Dendrite Morphogenesis Cellular Response To Organic Substance
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane
Drugs			Estramustine Paclitaxel Docetaxel
Diseases
GWAS
Protein-Protein Interactions		28 interactors: CDC42 HGS HNRNPK HPS6 KHDRBS3 KRT31 KRT40 MAP2 MAP4 MAPT MTUS2 NEDD4 NOTCH2NL ODF2 PARD6A PNMA1 PRKCG PRKCI PRNP RPTOR STK11 TUBA4A TUBB TUBG1 UBC YWHAB YWHAH YWHAZ	24 interactors: ACTB ACTN1 APOE APP CPEB1 DAG1 FYN GRB2 GRIN1 GRIN2D JUNB MARK1 MARK3 MARK4 MYO7A NEDD4L NEFL PAFAH1B1 PLEC PRKACA PRKAR2A SRC TTBK1 TUBA1A
Entrez ID		57787	4133
HPRD ID		09402	01140
Ensembl ID		ENSG00000007047	ENSG00000078018
Uniprot IDs		Q96L34	P11137 Q6NYC5
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Localization G2/M Transition Of Mitotic Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Establishment Of Localization In Cell Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Golgi Localization Regulation Of Cell Projection Organization Positive Regulation Of Transport Cell Cycle Cell Cycle Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Intracellular Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Neuron Development Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Microtubule Cytoskeleton Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cellular Localization Regulation Of Cell Morphogenesis Response To Stimulus Microtubule-based Process Regulation Of Apoptotic Process Cellular Response To Organic Substance Cellular Component Assembly Establishment Of Golgi Localization Neuron Differentiation Cytoskeleton Organization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Response To Stress Axonogenesis Regulation Of Cellular Component Organization Neuron Projection Development Negative Regulation Of ERBB Signaling Pathway Regulation Of Cell Death Generation Of Neurons Membrane Organization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Glucocorticoid Receptor Signaling Pathway Neurogenesis	Response To Peptide Hormone Response To Peptide Axon Development Response To Organonitrogen Compound Nervous System Development Cellular Component Assembly Neuron Development Response To Wounding Platelet Activation Neuron Projection Development Cell Morphogenesis Involved In Neuron Differentiation Neuron Differentiation Neuromuscular Process Cell Projection Organization Movement Of Cell Or Subcellular Component Blood Coagulation Neuron Projection Morphogenesis Hemostasis Generation Of Neurons Response To Hormone Locomotion Neurogenesis Cell Morphogenesis Involved In Differentiation Axonogenesis Cell Morphogenesis Cell Development Response To Abiotic Stimulus Cellular Response To Growth Factor Stimulus Cell Projection Morphogenesis Regulation Of Body Fluid Levels Response To Growth Factor Cell Part Morphogenesis Axon Guidance Chemotaxis Wound Healing Anatomical Structure Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway System Development Response To Organic Substance Transport Cell Surface Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Response To External Stimulus Epidermal Growth Factor Receptor Signaling Pathway Cellular Response To Peptide Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Cell Differentiation Cytoskeleton Organization Multicellular Organismal Development
Tagcloud ?		acetate activator antimetastatic ap atra benzamido benzoic bis consequently cytotoxicity derivative includes interfering inverted l5 metalloproteinase mmp noncytotoxic partly plasminogen proteolytic question tac tetradecanoylphorbol tpa trimethylsilyl urokinase zymographic	amorphous angiopathy autopsy congophilic cortices filaments frontal granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally
Tagcloud (Difference) ?		acetate activator antimetastatic ap atra benzamido benzoic bis consequently cytotoxicity derivative includes interfering inverted l5 metalloproteinase mmp noncytotoxic partly plasminogen proteolytic question tac tetradecanoylphorbol tpa trimethylsilyl urokinase zymographic	amorphous angiopathy autopsy congophilic cortices filaments frontal granular helical histologically immunolabeled immunolabeling immunolocalized map5 myelin neurofibrillary pallor plaques plastic pyramidal remarkable senile somata spongy sprouting stronger tangles temporal ultrastructurally
Tagcloud (Intersection) ?