MARK4 and ODF2

Number of citations of the paper that reports this interaction (PMID 23400999)
9

Data Source:
BioGRID (enzymatic study)

		MARK4	ODF2
Gene Name		MAP/microtubule affinity-regulating kinase 4	outer dense fiber of sperm tails 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Centrosome Microtubule Organizing Center Cytosol Microtubule Cytoskeleton Neuron Projection	Spindle Pole Outer Dense Fiber Nucleus Centrosome Centriole Cytosol Microtubule Ciliary Basal Body Primary Cilium
	Molecular Function	Protein Serine/threonine Kinase Activity Protein Binding ATP Binding Microtubule Binding Gamma-tubulin Binding Ubiquitin Binding Tau-protein Kinase Activity	Structural Molecule Activity Protein Binding Rab GTPase Binding
	Biological Process	Microtubule Cytoskeleton Organization Microtubule Bundle Formation Protein Phosphorylation Organelle Organization Nervous System Development Positive Regulation Of Programmed Cell Death	G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Organelle Organization Multicellular Organismal Development Spermatid Development Regulation Of Cilium Assembly
Pathways		Organelle biogenesis and maintenance Assembly of the primary cilium Anchoring of the basal body to the plasma membrane	Organelle biogenesis and maintenance Loss of proteins required for interphase microtubule organizationÂ from the centrosome Loss of Nlp from mitotic centrosomes G2/M Transition Assembly of the primary cilium Centrosome maturation Regulation of PLK1 Activity at G2/M Transition Mitotic G2-G2/M phases Anchoring of the basal body to the plasma membrane Recruitment of mitotic centrosome proteins and complexes Cell Cycle, Mitotic
Drugs
Diseases
GWAS
Protein-Protein Interactions		28 interactors: CDC42 HGS HNRNPK HPS6 KHDRBS3 KRT31 KRT40 MAP2 MAP4 MAPT MTUS2 NEDD4 NOTCH2NL ODF2 PARD6A PNMA1 PRKCG PRKCI PRNP RPTOR STK11 TUBA4A TUBB TUBG1 UBC YWHAB YWHAH YWHAZ	7 interactors: APP FBXO25 MARK4 ODF1 RAB8A SVIL ZDHHC17
Entrez ID		57787	4957
HPRD ID		09402	03601
Ensembl ID		ENSG00000007047	ENSG00000136811
Uniprot IDs		Q96L34	B3KSD5 B4DUU0 B4DX03 B4DX85 Q5BJF6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Localization G2/M Transition Of Mitotic Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Establishment Of Localization In Cell Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Golgi Localization Regulation Of Cell Projection Organization Positive Regulation Of Transport Cell Cycle Cell Cycle Process Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Intracellular Transport Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Neuron Development Positive Regulation Of Intracellular Transport Regulation Of Intracellular Transport Microtubule Cytoskeleton Organization Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Cellular Localization Regulation Of Cell Morphogenesis Response To Stimulus Microtubule-based Process Regulation Of Apoptotic Process Cellular Response To Organic Substance Cellular Component Assembly Establishment Of Golgi Localization Neuron Differentiation Cytoskeleton Organization Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Response To Stress Axonogenesis Regulation Of Cellular Component Organization Neuron Projection Development Negative Regulation Of ERBB Signaling Pathway Regulation Of Cell Death Generation Of Neurons Membrane Organization Axon Development Cell Morphogenesis Involved In Neuron Differentiation Apoptotic Signaling Pathway Positive Regulation Of Mitochondrion Organization Glucocorticoid Receptor Signaling Pathway Neurogenesis
Tagcloud ?		acetate activator antimetastatic ap atra benzamido benzoic bis consequently cytotoxicity derivative includes interfering inverted l5 metalloproteinase mmp noncytotoxic partly plasminogen proteolytic question tac tetradecanoylphorbol tpa trimethylsilyl urokinase zymographic	a3 a8 alpine androstenedione bucks cyp11a1 diameters fshr goat goats gsta3 haploid histoarchitecture hspa8 isomerization lhcgr livestock luteinizing marking maturity mo prm1 protamine1 seminiferous sox9 steadily stra8 testes testicular
Tagcloud (Difference) ?		acetate activator antimetastatic ap atra benzamido benzoic bis consequently cytotoxicity derivative includes interfering inverted l5 metalloproteinase mmp noncytotoxic partly plasminogen proteolytic question tac tetradecanoylphorbol tpa trimethylsilyl urokinase zymographic	a3 a8 alpine androstenedione bucks cyp11a1 diameters fshr goat goats gsta3 haploid histoarchitecture hspa8 isomerization lhcgr livestock luteinizing marking maturity mo prm1 protamine1 seminiferous sox9 steadily stra8 testes testicular
Tagcloud (Intersection) ?