PTPN1 and JAK2

Number of citations of the paper that reports this interaction (PubMedID 11694501)
0

Data Source:
HPRD (in vivo)

		PTPN1	JAK2
Description		protein tyrosine phosphatase non-receptor type 1	Janus kinase 2
Image
GO Annotations	Cellular Component	Cytoplasm Mitochondrial Matrix Early Endosome Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane Mitochondrial Crista Endosome Lumen Protein-containing Complex Sorting Endosome Cytoplasmic Side Of Endoplasmic Reticulum Membrane Postsynapse Glutamatergic Synapse	Euchromatin Nucleus Nucleoplasm Cytoplasm Endosome Cytosol Plasma Membrane Caveola Focal Adhesion Cytoplasmic Side Of Plasma Membrane Endomembrane System Membrane Extrinsic Component Of Plasma Membrane Granulocyte Macrophage Colony-stimulating Factor Receptor Complex Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Endosome Lumen Interleukin-12 Receptor Complex Membrane Raft Interleukin-23 Receptor Complex Postsynapse Glutamatergic Synapse
	Molecular Function	RNA Binding Phosphoprotein Phosphatase Activity Protein Tyrosine Phosphatase Activity Non-membrane Spanning Protein Tyrosine Phosphatase Activity Insulin Receptor Binding Protein Binding Zinc Ion Binding Hydrolase Activity Phosphatase Activity Enzyme Binding Protein Kinase Binding Receptor Tyrosine Kinase Binding Cadherin Binding Ephrin Receptor Binding Protein Phosphatase 2A Binding	Nucleotide Binding Protein Kinase Activity Protein Tyrosine Kinase Activity Non-membrane Spanning Protein Tyrosine Kinase Activity Signaling Receptor Binding Growth Hormone Receptor Binding Interleukin-12 Receptor Binding Protein Binding ATP Binding Kinase Activity Transferase Activity Protein Kinase Binding Heme Binding Signaling Receptor Activator Activity Type 1 Angiotensin Receptor Binding Acetylcholine Receptor Binding Histone H3Y41 Kinase Activity SH2 Domain Binding Histone Binding Identical Protein Binding Phosphatidylinositol 3-kinase Binding Insulin Receptor Substrate Binding Metal Ion Binding Peptide Hormone Receptor Binding
	Biological Process	Positive Regulation Of Systemic Arterial Blood Pressure Protein Dephosphorylation Negative Regulation Of Cell Population Proliferation Insulin Receptor Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Signal Transduction Positive Regulation Of Heart Rate Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Negative Regulation Of Cell-substrate Adhesion Negative Regulation Of Neuron Projection Development Actin Cytoskeleton Organization Regulation Of Endocytosis Regulation Of Proteolysis Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Endoplasmic Reticulum Unfolded Protein Response Response To Nutrient Levels Cellular Response To Insulin Stimulus Regulation Of Intracellular Protein Transport Cellular Response To Unfolded Protein Response To Endoplasmic Reticulum Stress Peptidyl-tyrosine Dephosphorylation Platelet-derived Growth Factor Receptor-beta Signaling Pathway Cellular Response To Platelet-derived Growth Factor Stimulus IRE1-mediated Unfolded Protein Response Insulin Receptor Recycling Negative Regulation Of MAP Kinase Activity Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of JNK Cascade Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Insulin Receptor Signaling Pathway Negative Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Regulation Of Type I Interferon-mediated Signaling Pathway Growth Hormone Receptor Signaling Pathway Via JAK-STAT Negative Regulation Of ERK1 And ERK2 Cascade Cellular Response To Hypoxia Cellular Response To Nitric Oxide Vascular Endothelial Cell Response To Oscillatory Fluid Shear Stress Regulation Of Postsynapse Assembly Regulation Of Hepatocyte Growth Factor Receptor Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of IRE1-mediated Unfolded Protein Response Negative Regulation Of PERK-mediated Unfolded Protein Response Cellular Response To Angiotensin Negative Regulation Of Vascular Associated Smooth Muscle Cell Migration Cellular Response To Nerve Growth Factor Stimulus Response To Angiotensin Positive Regulation Of Endothelial Cell Apoptotic Process Positive Regulation Of Receptor Catabolic Process	Microglial Cell Activation Positive Regulation Of Cytokine Production Adaptive Immune Response Immune System Process Chromatin Organization Chromatin Remodeling Transcription By RNA Polymerase II Apoptotic Process Immune Response Response To Oxidative Stress Cell Adhesion Signal Transduction Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Cytosolic Calcium Ion Concentration Cell Surface Receptor Signaling Pathway Via JAK-STAT Mesoderm Development Positive Regulation Of Cell Population Proliferation Negative Regulation Of Cell Population Proliferation Intrinsic Apoptotic Signaling Pathway In Response To Oxidative Stress Hormone-mediated Signaling Pathway Positive Regulation Of Platelet Activation Negative Regulation Of Cardiac Muscle Cell Apoptotic Process Positive Regulation Of Cell-substrate Adhesion Cytokine-mediated Signaling Pathway Regulation Of Cell-cell Adhesion Negative Regulation Of Cell-cell Adhesion Actin Filament Polymerization Myeloid Cell Differentiation Cell Differentiation Erythrocyte Differentiation Positive Regulation Of Cell Migration Axon Regeneration Lipopolysaccharide-mediated Signaling Pathway Nuclear Receptor-mediated Mineralocorticoid Signaling Pathway Positive Regulation Of Insulin Secretion Positive Regulation Of Type II Interferon Production Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-17 Production Positive Regulation Of Tumor Necrosis Factor Production Positive Regulation Of Natural Killer Cell Proliferation Response To Hydroperoxide Tumor Necrosis Factor-mediated Signaling Pathway Symbiont-induced Defense-related Programmed Cell Death Response To Tumor Necrosis Factor Post-embryonic Hemopoiesis Intracellular Signal Transduction Interleukin-12-mediated Signaling Pathway Cellular Response To Interleukin-3 Interleukin-5-mediated Signaling Pathway Collagen-activated Signaling Pathway Interleukin-23-mediated Signaling Pathway Interleukin-3-mediated Signaling Pathway Granulocyte-macrophage Colony-stimulating Factor Signaling Pathway Erythropoietin-mediated Signaling Pathway Thrombopoietin-mediated Signaling Pathway Positive Regulation Of T Cell Proliferation Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Tyrosine Phosphorylation Of STAT Protein Activation Of Janus Kinase Activity Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of MAPK Cascade Negative Regulation Of Neuron Apoptotic Process Post-translational Protein Modification T-helper 1 Cell Differentiation Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Nitric Oxide Biosynthetic Process Positive Regulation Of Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Receptor Signaling Pathway Via JAK-STAT Regulation Of Alpha-beta T Cell Activation Response To Antibiotic Protein Autophosphorylation Platelet-derived Growth Factor Receptor Signaling Pathway Regulation Of Inflammatory Response Modulation Of Chemical Synaptic Transmission Positive Regulation Of Cell Activation Positive Regulation Of NK T Cell Proliferation Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Type II Interferon-mediated Signaling Pathway Positive Regulation Of SMAD Protein Signal Transduction Growth Hormone Receptor Signaling Pathway Growth Hormone Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Growth Hormone Receptor Signaling Pathway Negative Regulation Of Growth Hormone Receptor Signaling Pathway Mammary Gland Epithelium Development Interleukin-6-mediated Signaling Pathway Positive Regulation Of Leukocyte Proliferation Response To Interleukin-12 Interleukin-35-mediated Signaling Pathway Cellular Response To Lipopolysaccharide Cellular Response To Dexamethasone Stimulus Extrinsic Apoptotic Signaling Pathway Cellular Response To Virus Positive Regulation Of Cold-induced Thermogenesis Defense Response To Symbiont Negative Regulation Of Cytokine Production Involved In Inflammatory Response Positive Regulation Of Platelet Aggregation Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Growth Factor Dependent Skeletal Muscle Satellite Cell Proliferation Positive Regulation Of Epithelial Cell Apoptotic Process Positive Regulation Of Vascular Associated Smooth Muscle Cell Proliferation Regulation Of Postsynapse To Nucleus Signaling Pathway Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Positive Regulation Of T-helper 17 Type Immune Response Positive Regulation Of Apoptotic Signaling Pathway
Pathways		Integrin signaling Negative regulation of MET activity Insulin receptor recycling Regulation of IFNG signaling PTK6 Down-Regulation MECP2 regulates neuronal receptors and channels Regulation of IFNA/IFNB signaling Growth hormone receptor signaling Growth hormone receptor signaling Turbulent (oscillatory, disturbed) flow shear stress activates signaling by PIEZO1 and integrins in endothelial cells	Interleukin-6 signaling Interleukin-6 signaling MAPK3 (ERK1) activation MAPK1 (ERK2) activation Prolactin receptor signaling Prolactin receptor signaling Signaling by SCF-KIT Signaling by Leptin RMTs methylate histone arginines Interleukin-3, Interleukin-5 and GM-CSF signaling Interleukin-3, Interleukin-5 and GM-CSF signaling RAF activation RAF/MAP kinase cascade Interleukin-4 and Interleukin-13 signaling IL-6-type cytokine receptor ligand interactions Signaling by moderate kinase activity BRAF mutants Signaling by BRAF and RAF1 fusions Paradoxical activation of RAF signaling by kinase inactive BRAF Cyclin D associated events in G1 Interferon gamma signaling Regulation of IFNG signaling Regulation of IFNG signaling Interleukin-20 family signaling Interleukin-35 Signalling Signaling by Erythropoietin Signaling by Erythropoietin Interleukin-12 signaling Interleukin-12 signaling Interleukin-23 signaling Interleukin-23 signaling Interleukin-27 signaling Interleukin-27 signaling Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Erythropoietin activates Phosphoinositide-3-kinase (PI3K) Erythropoietin activates Phospholipase C gamma (PLCG) Erythropoietin activates STAT5 Erythropoietin activates RAS Erythropoietin activates RAS Interleukin receptor SHC signaling Signaling downstream of RAS mutants Signaling by RAF1 mutants Signaling by phosphorylated juxtamembrane, extracellular and kinase domain KIT mutants Signaling by CSF3 (G-CSF) Signaling by CSF3 (G-CSF) Potential therapeutics for SARS Inactivation of CSF3 (G-CSF) signaling Inactivation of CSF3 (G-CSF) signaling IFNG signaling activates MAPKs Growth hormone receptor signaling Growth hormone receptor signaling Factors involved in megakaryocyte development and platelet production
Drugs		3-(Oxalyl-Amino)-Naphthalene-2-Carboxylic Acid 2-{[4-(2-Acetylamino-2-pentylcarbamoyl-ethyl)-naphthalen-1-YL]-oxalyl-amino}-benzoic acid 5-(2-Fluoro-5-{(1E)-3-[3-hydroxy-2-(methoxycarbonyl)phenoxy]-1-propen-1-yl}phenyl)-1,2-oxazole-3-carboxylic acid 2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Thiopyran-3-Carboxylic Acid 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid (4-Sulfamoyl-Phenyl)-Amide [[4-(Aminomethyl)Phenyl]Amino]Oxo-Acetic Acid, {4-[(2S)-2-({[(1S)-1-Carboxy-2-phenylethyl]carbamoyl}amino)-3-oxo-3-(pentylamino)propyl]phenoxy}malonic acid Compound 19 3-(4-{2-[2-(2-bromo-acetylamino)-ethyldisulfanyl]-ethylcarbamoyl}-cyclohexylcarbamoyl)-pyrazine-2-carboxylic acid 2-(Oxalyl-Amino)-Benzoic Acid {[2-(1h-1,2,3-Benzotriazol-1-Yl)-2-(3,4-Difluorophenyl)Propane-1,3-Diyl]Bis[4,1-Phenylene(Difluoromethylene)]}Bis(Phosphonic Acid) Novo Nordisk a/S Compound N-(Bromoacetyl)-beta-alanyl-N-(2-{4-[(carboxycarbonyl)amino]phenyl}ethyl)-L-serinamide 7-(1,1-Dioxo-1h-Benzo[D]Isothiazol-3-Yloxymethyl)-2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid PNU177836 2-(Oxalyl-Amino)-4,7-Dihydro-5h-Thieno[2,3-C]Pyran-3-Carboxylic Acid {[7-(Difluoro-Phosphono-Methyl)-Naphthalen-2-Yl]-Difluoro-Methyl}-Phosphonic Acid 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid [4-(Thiazol-2-Ylsulfamoyl)-Phenyl]-Amide (4S)-5-[[(2S)-1-[[(2S)-1-Amino-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-4-benzamido-5-oxopentanoic acid 4-[[(2S)-1-[[6-[(1-Amino-1-oxo-3-sulfanylpropan-2-yl)amino]-6-oxohexyl]amino]-3-[4-[difluoro(phosphono)methyl]phenyl]-1-oxopropan-2-yl]amino]-3-[[2-[4-[difluoro(phosphono)methyl]phenyl]acetyl]amino]-4-oxobutanoic acid L-cysteic acid 2-(Oxalyl-Amino)-4,5,6,7-Tetrahydro-Thieno[2,3-C]Pyridine-3-Carboxylic Acid -Carbonyl]-Amino}-Butyric Acid Compound 5, 2-(Naphthalen-1-Yl-Oxalyl-Amino)-Benzoicacid 6-(Oxalyl-Amino)-1h-Indole-5-Carboxylic Acid 2-[{4-[(2S)-2-{[(Allyloxy)carbonyl]amino}-3-({4-[3-hydroxy-2-(methoxycarbonyl)phenoxy]butyl}amino)-3-oxopropyl]phenyl}(carboxycarbonyl)amino]benzoic acid 3-(3,5-Dibromo-4-Hydroxy-Benzoyl)-2-Ethyl-Benzofuran-6-Sulfonic Acid Dimethylamide [(4-{4-[4-(Difluoro-Phosphono-Methyl)-Phenyl]-Butyl}-Phenyl)-Difluoro-Methyl]-Phosphonic Acid {4-[(2s,4e)-2-(1,3-Benzothiazol-2-Yl)-2-(1h-1,2,3-Benzotriazol-1-Yl)-5-Phenylpent-4-Enyl]Phenyl}(Difluoro)Methylphosphonic Acid N-(3-Carboxypropanoyl)-L-phenylalanyl-3-carboxy-O-(carboxymethyl)-N-pentyl-L-tyrosinamide 1-METHYL-3-PHENYL-1H-PYRAZOL-5-YLSULFAMIC ACID ISIS 113715 Trodusquemine Ertiprotafib 4-BROMO-3-(CARBOXYMETHOXY)-5-[3-(CYCLOHEXYLAMINO)PHENYL]THIOPHENE-2-CARBOXYLIC ACID [(3S)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid 4-BROMO-3-(CARBOXYMETHOXY)-5-PHENYLTHIOPHENE-2-CARBOXYLIC ACID 5-(4-CHLORO-5-PHENYL-3-THIENYL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE 4-BROMO-3-(CARBOXYMETHOXY)-5-(4-HYDROXYPHENYL)THIOPHENE-2-CARBOXYLIC ACID [{2-bromo-4-[(2R)-3-oxo-2,3-diphenylpropyl]phenyl}(difluoro)methyl]phosphonic acid 5-[3-(BENZYLAMINO)PHENYL]-4-BROMO-3-(CARBOXYMETHOXY)THIOPHENE-2-CARBOXYLIC ACID 2-[(7-HYDROXY-NAPHTHALEN-1-YL)-OXALYL-AMINO]-BENZOIC ACID 3-(CARBOXYMETHOXY)THIENO[2,3-B]PYRIDINE-2-CARBOXYLIC ACID 4-PHOSPHONOOXY-PHENYL-METHYL-[4-PHOSPHONOOXY]BENZEN N-ACETYL-L-PHENYLALANYL-4-[DIFLUORO(PHOSPHONO)METHYL]-L-PHENYLALANINAMIDE [(3R)-3-(Methylcarbamoyl)-2-{[(2-methyl-2-propanyl)oxy]carbonyl}-1,2,3,4-tetrahydro-7-isoquinolinyl]sulfamic acid 5-(3-HYDROXYPHENYL)ISOTHIAZOL-3(2H)-ONE 1,1-DIOXIDE 5-(3-{3-[3-HYDROXY-2-(METHOXYCARBONYL)PHENOXY]PROPENYL}PHENYL)-4-(HYDROXYMETHYL)ISOXAZOLE-3-CARBOXYLIC ACID ISOTHIAZOLIDINONE ANALOG 4-[3-(dibenzylamino)phenyl]-2,4-dioxobutanoic acid p-Benzoyl-L-phenylalanine 6-(DIFLUORO-PHOSPHONO-METHYL)-NAPHTHALENE-2-CARBOXYLIC ACID (3R)-METHYLCARBAMOYL-7-SULFOAMINO-3,4-DIHYDRO-1H-ISOQUINOLINE-2-CARBOXYLIC ACID BENZYL ESTER 5-(4-METHOXYBIPHENYL-3-YL)-1,2,5-THIADIAZOLIDIN-3-ONE 1,1-DIOXIDE 1,2,5-THIADIAZOLIDIN-3-ONE-1,1-DIOXIDE (4-{(2S)-2-[(tert-butoxycarbonyl)amino]-3-methoxy-3-oxopropyl}phenyl)methaneseleninic acid	2-tert-butyl-9-fluoro-1,6-dihydrobenzo[h]imidazo[4,5-f]isoquinolin-7-one XL019 5-phenyl-1H-indazol-3-amine 4-(3-amino-1H-indazol-5-yl)-N-tert-butylbenzenesulfonamide 4-[(2-{4-[(CYCLOPROPYLCARBAMOYL)AMINO]-1H-PYRAZOL-3-YL}-1H-BENZIMIDAZOL-6-YL)METHYL]MORPHOLIN-4-IUM Ruxolitinib Tofacitinib Pacritinib Baricitinib Entrectinib Fostamatinib Fedratinib Abrocitinib Zanubrutinib Pralsetinib
Diseases			Polycythemia vera
GWAS		Appendicular lean mass ( 33097823) Basophil count ( 32888494) Colorectal cancer ( 30529582 31826910) Colorectal cancer or advanced adenoma ( 30510241) Eosinophil count ( 32888494) Eosinophil percentage of white cells ( 32888494) Intraocular pressure ( 29617998 29785010 30054594 31959993) Lymphocyte percentage of white cells ( 32888494) Thyroid stimulating hormone levels ( 30843173) Vitiligo ( 27723757)	Allergic disease (asthma, hay fever or eczema) ( 29083406) Chronic inflammatory diseases (ankylosing spondylitis, Crohn's disease, psoriasis, primary sclerosing cholangitis, ulcerative colitis) (pleiotropy) ( 26974007) Crohn's disease ( 18587394 21102463 23266558) Eosinophil count ( 32888494 27863252) Eosinophil percentage of white cells ( 32888494) Eosinophilic esophagitis ( 34506852) HDL cholesterol ( 30275531) Height ( 31562340) Inflammatory bowel disease ( 23128233) LDL cholesterol ( 30275531) Mean corpuscular hemoglobin ( 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte percentage of white cells ( 32888494) Myeloproliferative neoplasms ( 19287384 25849990 33057200) Neutrophil count ( 32888494) Pediatric autoimmune diseases ( 26301688) Platelet count ( 24777453 32888494 27863252 28031487) Plateletcrit ( 27863252 32888494) Psoriatic arthritis ( 26626624) Red blood cell count ( 32888494) Sum eosinophil basophil counts ( 27863252) Systemic lupus erythematosus ( 27399966 33272962) Total cholesterol levels ( 30275531) Ulcerative colitis ( 19915573 20228799 21297633 26398853) White blood cell count ( 32888494)
Interacting Genes		68 interacting genes: ABL1 ACTN1 AGR3 AKT1 AQP6 ASS1 BCAR1 BCAS3 BCR CAPN2 CASC3 CASZ1 CAV1 CCL5 CDH13 CDH2 CDK1 CLK1 CLK2 COP1 CRK CSNK2A1 CSNK2A2 CTNNB1 DIRAS3 EGFR ELOVL4 ESR1 FGFR1 GHR GLRX GRB2 GSK3B IGF1R INSR IRS1 JAK2 KLK7 LAT LRATD2 LTK MAPK1 MRC2 NFKBIA NTRK1 NTRK2 NTRK3 PDGFRB PIAS1 PIGP PIN1 PRKCA RHOBTB2 RRAS2 SNAI1 SRC STAM2 STAT3 STAT5A STAT5B THRSP TIMMDC1 TMEM31 TMEM41A TMEM86B TRPV6 TYK2 VPS45	99 interacting genes: ABL1 AGTR1 ARL11 ASS1 BCR BRCA1 CBL CCR5 CISH CRLF2 CSF2RB CSF3R CTLA4 CXCR4 DNAJA3 EGFR ELP2 EPOR ERBB2 ERBB3 EZH2 FES FYN GHR GRB10 GRB2 GTF2I H3-4 HES1 HES5 HSFY1 HSPA8 HTR2A IFNGR1 IFNGR2 IGF1R IKBKG IL12RB2 IL23R IL3RA IL4R IL5RA INSR IRS1 IRS2 JAK1 JAK3 KIT LEPR LYN MAP3K5 MDK MPL MST1R NFKBIA OSMR PDGFRB PIK3R1 PKD1 PLCG2 PPIA PPP1CC PPP2CA PPP2R1B PPP2R5A PRLR PRMT5 PTK2 PTK2B PTPN1 PTPN11 PTPN12 PTPN6 PTPRC RAF1 RBMX SH2B1 SH2B2 SHC1 SIRPA SOCS1 SOCS3 STAM STAM2 STAP2 STAT1 STAT2 STAT3 STAT5A STAT5B TEC TNFRSF1A TRAF6 TSHR TUB UBASH3B VAV1 VCP YES1
Entrez ID		5770	3717
HPRD ID		01477	00993
Ensembl ID		ENSG00000196396	ENSG00000096968
Uniprot IDs		A8K3M3 B4DSN5 P18031	A8K910 B4DYV1 O60674
PDB IDs		1A5Y 1AAX 1BZC 1BZH 1BZJ 1C83 1C84 1C85 1C86 1C87 1C88 1ECV 1EEN 1EEO 1G1F 1G1G 1G1H 1G7F 1G7G 1GFY 1I57 1JF7 1KAK 1KAV 1L8G 1LQF 1NL9 1NNY 1NO6 1NWE 1NWL 1NZ7 1OEM 1OEO 1OES 1OET 1OEU 1OEV 1ONY 1ONZ 1PA1 1PH0 1PTT 1PTU 1PTV 1PTY 1PXH 1PYN 1Q1M 1Q6J 1Q6M 1Q6N 1Q6P 1Q6S 1Q6T 1QXK 1SUG 1T48 1T49 1T4J 1WAX 1XBO 2AZR 2B07 2B4S 2BGD 2BGE 2CM2 2CM3 2CM7 2CM8 2CMA 2CMB 2CMC 2CNE 2CNF 2CNG 2CNH 2CNI 2F6F 2F6T 2F6V 2F6W 2F6Y 2F6Z 2F70 2F71 2FJM 2FJN 2H4G 2H4K 2HB1 2HNP 2HNQ 2NT7 2NTA 2QBP 2QBQ 2QBR 2QBS 2VEU 2VEV 2VEW 2VEX 2VEY 2ZMM 2ZN7 3A5J 3A5K 3CWE 3D9C 3EAX 3EB1 3EU0 3I7Z 3I80 3QKP 3QKQ 3SME 3ZMP 3ZMQ 3ZV2 4BJO 4I8N 4QAH 4QAP 4QBE 4QBW 4Y14 4ZRT 5K9V 5K9W 5KA0 5KA1 5KA2 5KA3 5KA4 5KA7 5KA8 5KA9 5KAA 5KAB 5KAC 5KAD 5QDE 5QDF 5QDG 5QDH 5QDI 5QDJ 5QDK 5QDL 5QDM 5QDN 5QDO 5QDP 5QDQ 5QDR 5QDS 5QDT 5QDU 5QDV 5QDW 5QDX 5QDY 5QDZ 5QE0 5QE1 5QE2 5QE3 5QE4 5QE5 5QE6 5QE7 5QE8 5QE9 5QEA 5QEB 5QEC 5QED 5QEE 5QEF 5QEG 5QEH 5QEI 5QEJ 5QEK 5QEL 5QEM 5QEN 5QEO 5QEP 5QEQ 5QER 5QES 5QET 5QEU 5QEV 5QEW 5QEX 5QEY 5QEZ 5QF0 5QF1 5QF2 5QF3 5QF4 5QF5 5QF6 5QF7 5QF8 5QF9 5QFA 5QFB 5QFC 5QFD 5QFE 5QFF 5QFG 5QFH 5QFI 5QFJ 5QFK 5QFL 5QFM 5QFN 5QFO 5QFP 5QFQ 5QFR 5QFS 5QFT 5QFU 5QFV 5QFW 5QFX 5QFY 5QFZ 5QG0 5QG1 5QG2 5QG3 5QG4 5QG5 5QG6 5QG7 5QG8 5QG9 5QGA 5QGB 5QGC 5QGD 5QGE 5QGF 5T19 6B8E 6B8T 6B8X 6B8Z 6B90 6B95 6BAI 6CWU 6CWV 6NTP 6OL4 6OLQ 6OLV 6OMY 6PFW 6PG0 6PGT 6PHA 6PHS 6PM8 6W30 6XE8 6XEA 6XED 6XEE 6XEF 6XEG 7FQM 7FQN 7FQO 7FQP 7FQQ 7FQR 7FQS 7FQT 7FQU 7FQV 7FQW 7FQX 7FQY 7FQZ 7FRE 7FRF 7FRG 7FRH 7FRI 7FRJ 7FRK 7FRL 7FRM 7FRN 7FRO 7FRP 7FRQ 7FRR 7FRS 7FRT 7FRU 7GS7 7GS8 7GS9 7GSA 7GSB 7GSC 7GSD 7GSE 7GSF 7GSG 7GSH 7GSI 7GSJ 7GSK 7GSL 7GSM 7GSN 7GSO 7GSQ 7GSR 7GST 7GSU 7GSV 7GSW 7GSX 7GSY 7GSZ 7GT0 7GT1 7GT2 7GT3 7GT4 7GT5 7GT6 7GT7 7GT8 7GT9 7GTA 7GTB 7GTC 7GTD 7GTE 7GTF 7GTG 7GTH 7GTI 7GTJ 7GTK 7GTL 7GTM 7GTN 7GTO 7GTP 7GTQ 7GTR 7GTS 7GTT 7GTU 7GTV 7GTW 7GTX 7GTY 7GTZ 7GU0 7GU1 7GU2 7GU3 7GU4 7GU5 7GU6 7GU7 7GU8 7GU9 7GUA 7GUB 7GUC 7KEN 7KEY 7KLX 7L0C 7L0H 7LFO 7MKZ 7MM1 7MN7 7MN9 7MNA 7MNB 7MNC 7MND 7MNE 7MNF 7MOU 7MOV 7MOW 7RIN 7S4F 8DU7 8EXI 8EXJ 8EXK 8EXM 8EXN 8EYA 8EYB 8EYC 8F88 8G65 8G67 8G68 8G69 8G6A 8SKL 8U1E 8XOY 9C66 9CYO 9CYP 9CYQ 9CYR	2B7A 2W1I 2XA4 3E62 3E63 3E64 3FUP 3IO7 3IOK 3JY9 3KCK 3KRR 3LPB 3Q32 3RVG 3TJC 3TJD 3UGC 3ZMM 4AQC 4BBE 4BBF 4C61 4C62 4D0W 4D0X 4D1S 4E4M 4E6D 4E6Q 4F08 4F09 4FVP 4FVQ 4FVR 4GFM 4GMY 4HGE 4IVA 4JI9 4JIA 4P7E 4YTC 4YTF 4YTH 4YTI 4Z32 4ZIM 5AEP 5CF4 5CF5 5CF6 5CF8 5HEZ 5I4N 5L3A 5TQ3 5TQ4 5TQ5 5TQ6 5TQ7 5TQ8 5USY 5USZ 5UT0 5UT1 5UT2 5UT3 5UT4 5UT5 5UT6 5WEV 5WIJ 5WIK 5WIL 5WIM 5WIN 6AAJ 6BBV 6BRW 6BS0 6BSS 6D2I 6DRW 6E2P 6E2Q 6G3C 6M9H 6OAV 6OBB 6OBF 6OBL 6OCC 6TPD 6VGL 6VN8 6VNB 6VNC 6VNE 6VNF 6VNG 6VNH 6VNI 6VNJ 6VNK 6VNL 6VNM 6VS3 6VSN 6WTN 6WTO 6WTP 6WTQ 6X8E 6XJK 7F7W 7JYO 7JYQ 7LL4 7LL5 7Q7I 7Q7K 7Q7L 7Q7W 7REE 7RN6 7SZW 7T0P 7T1T 7TEU 7UYW 8B8N 8B8U 8B99 8B9E 8B9H 8BA2 8BA3 8BA4 8BAB 8BAK 8BM2 8BPV 8BPW 8BX6 8BX9 8BXC 8BXH 8C08 8C09 8C0A 8CZ9 8EX0 8EX1 8EX2 8EXK 8EYA 8EYB 8F88 8G6Z 8G8O 8G8X
Enriched GO Terms of Interacting Partners?		Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Protein Tyrosine Kinase Activity Protein Kinase Activity Enzyme-linked Receptor Protein Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Kinase Activity Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Response To Growth Factor Phosphorylation Cellular Response To Growth Factor Stimulus Protein Phosphorylation Positive Regulation Of Cell Population Proliferation Cell Surface Receptor Signaling Pathway Regulation Of Cell Motility Regulation Of Intracellular Signal Transduction Regulation Of MAPK Cascade Protein Autophosphorylation Intracellular Signaling Cassette Regulation Of Locomotion Regulation Of Cell Population Proliferation Regulation Of Cell Migration Positive Regulation Of Intracellular Signal Transduction Transmembrane Receptor Protein Tyrosine Kinase Activity Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Negative Regulation Of Apoptotic Process Regulation Of Apoptotic Process Positive Regulation Of MAPK Cascade Response To Lipid Negative Regulation Of Programmed Cell Death Regulation Of Programmed Cell Death Positive Regulation Of Signal Transduction Positive Regulation Of Cell Communication Positive Regulation Of Signaling Cellular Response To Oxygen-containing Compound Positive Regulation Of Metabolic Process Growth Hormone Receptor Signaling Pathway Via JAK-STAT Signal Transduction Enzyme Binding Intracellular Signal Transduction Nucleotide Binding Epidermal Growth Factor Receptor Signaling Pathway Positive Regulation Of Biosynthetic Process Protein Kinase Binding Regulation Of Signal Transduction SH2 Domain Binding Cell Population Proliferation ATP Binding Receptor Complex	Cell Surface Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Signal Transduction Positive Regulation Of Cell Population Proliferation Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cell Population Proliferation Regulation Of Multicellular Organismal Process Enzyme-linked Receptor Protein Signaling Pathway Cytokine Receptor Activity Regulation Of Signal Transduction Cell Surface Receptor Signaling Pathway Via STAT Receptor Complex Cell Surface Receptor Signaling Pathway Via JAK-STAT Positive Regulation Of Multicellular Organismal Process Regulation Of Cell Adhesion Plasma Membrane Regulation Of Signaling Regulation Of Cell Communication Protein Tyrosine Kinase Activity Immune System Process Regulation Of Immune System Process Positive Regulation Of Signal Transduction Cytokine Binding Regulation Of Cell Differentiation Regulation Of Developmental Process Positive Regulation Of Cell Communication Positive Regulation Of Signaling Regulation Of Cell-cell Adhesion Positive Regulation Of Metabolic Process Positive Regulation Of Immune System Process Regulation Of Cell Activation Cell Activation Intracellular Signal Transduction Positive Regulation Of Intracellular Signal Transduction Regulation Of Intracellular Signal Transduction Regulation Of Multicellular Organismal Development Regulation Of Cell Development Positive Regulation Of Lymphocyte Activation Regulation Of Leukocyte Cell-cell Adhesion Phosphotyrosine Residue Binding Positive Regulation Of Cell Activation Growth Hormone Receptor Signaling Pathway Leukocyte Activation Regulation Of Lymphocyte Activation Positive Regulation Of Cell-cell Adhesion Regulation Of Hemopoiesis Regulation Of MAPK Cascade Regulation Of Programmed Cell Death Response To Cytokine Regulation Of T Cell Activation
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