FANCM and C19orf40

Number of citations of the paper that reports this interaction (PMID 17289582)
99

Data Source:
HPRD (two hybrid, in vivo)

		FANCM	C19orf40
Gene Name		Fanconi anemia, complementation group M	chromosome 19 open reading frame 40
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex	Nucleoplasm Intracellular Membrane-bounded Organelle Fanconi Anaemia Nuclear Complex
	Molecular Function	DNA Binding Chromatin Binding Helicase Activity Nuclease Activity Protein Binding ATP Binding	DNA Binding Chromatin Binding Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates DNA Repair Replication Fork Processing Nucleic Acid Phosphodiester Bond Hydrolysis	DNA Repair
Pathways		Fanconi Anemia pathway	Fanconi Anemia pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APITD1 APP C19orf40 ECT2 EME2 STRA13 SUMO1 TRIM27	4 interactors: APP EME2 FANCM TERT
Entrez ID		57697	91442
HPRD ID		13876	14547
Ensembl ID		ENSG00000187790
Uniprot IDs		B2RTQ9 Q8IYD8	K7EKQ4 Q9BTP7
PDB IDs		4BXO 4DAY 4DRB 4E45	2LYH 2M9M 2M9N 4BXO 4M6W
Enriched GO Terms of Interacting Partners?		Response To Stress DNA Repair Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Cellular Protein Metabolic Process Resolution Of Meiotic Recombination Intermediates DNA Metabolic Process Replication Fork Processing Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Chromosome Separation CENP-A Containing Nucleosome Assembly Cellular Response To Stimulus DNA Recombination Histone Exchange DNA Replication-independent Nucleosome Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Reciprocal Meiotic Recombination Centromere Complex Assembly Cellular Nitrogen Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Response To Stimulus Protein Complex Assembly Reproduction ATP-dependent Chromatin Remodeling Nitrogen Compound Metabolic Process Cell Division Meiotic Chromosome Segregation Response To Radiation Meiosis I DNA-dependent DNA Replication Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleosome Assembly Chromatin Assembly Positive Regulation Of Protein Ubiquitination Collateral Sprouting In Absence Of Injury Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly PML Body Organization Meiotic Nuclear Division Positive Regulation Of Protein Complex Assembly Regulation Of Protein Kinase Activity	Negative Regulation Of Production Of SiRNA Involved In RNA Interference Negative Regulation Of RNA Interference Transcription, RNA-templated Synaptic Growth At Neuromuscular Junction DNA Metabolic Process Collateral Sprouting In Absence Of Injury Age-dependent Telomere Shortening Telomere Formation Via Telomerase DNA Recombination Telomere Maintenance Via Telomere Shortening Collateral Sprouting Axon Midline Choice Point Recognition DNA Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Nucleic Acid Phosphodiester Bond Hydrolysis Axon Choice Point Recognition Telomere Assembly Nucleobase-containing Compound Metabolic Process Neuron Remodeling Replicative Cell Aging Telomere Maintenance Via Telomerase Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Production Of SiRNA Involved In RNA Interference Cellular Nitrogen Compound Metabolic Process Posttranscriptional Regulation Of Gene Expression Resolution Of Meiotic Recombination Intermediates RNA Interference Replication Fork Processing Replicative Senescence Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis RNA Processing RNA-dependent DNA Replication DNA Repair Regulation Of Gene Silencing Chromosome Separation Copper Ion Homeostasis Suckling Behavior Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity DNA Strand Elongation Telomere Maintenance Via Telomere Lengthening Mating Behavior Endoplasmic Reticulum Calcium Ion Homeostasis Cellular Response To Stimulus RNA Polyadenylation Cellular Response To DsRNA
Tagcloud ?		anemia arise atm deficiency encoding failure fanconi fertility germ hypogonadism includes instability maintenance males meiotic neonates overlaid partially pgcs phenotypes primordial progressive propagate propagation repair sexes testicular true
Tagcloud (Difference) ?		anemia arise atm deficiency encoding failure fanconi fertility germ hypogonadism includes instability maintenance males meiotic neonates overlaid partially pgcs phenotypes primordial progressive propagate propagation repair sexes testicular true
Tagcloud (Intersection) ?