FANCM and STRA13

Number of citations of the paper that reports this interaction (PMID 20347428)
54

Data Source:
BioGRID (pull down)

		FANCM	STRA13
Gene Name		Fanconi anemia, complementation group M	stimulated by retinoic acid 13
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex	Condensed Chromosome Kinetochore Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex
	Molecular Function	DNA Binding Chromatin Binding Helicase Activity Nuclease Activity Protein Binding ATP Binding	DNA Binding Double-stranded DNA Binding Protein Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates DNA Repair Replication Fork Processing Nucleic Acid Phosphodiester Bond Hydrolysis	Resolution Of Meiotic Recombination Intermediates DNA Repair Nucleosome Assembly Mitotic Nuclear Division Replication Fork Processing Positive Regulation Of Protein Ubiquitination CENP-A Containing Nucleosome Assembly Cell Division Kinetochore Assembly
Pathways		Fanconi Anemia pathway	Chromosome Maintenance Nucleosome assembly Deposition of new CENPA-containing nucleosomes at the centromere
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: APITD1 APP C19orf40 ECT2 EME2 STRA13 SUMO1 TRIM27	7 interactors: APITD1 FANCM NKX3-1 REL TP53 TRIM54 UBE2I
Entrez ID		57697	201254
HPRD ID		13876	18121
Ensembl ID		ENSG00000187790	ENSG00000169689
Uniprot IDs		B2RTQ9 Q8IYD8	A8MT69 J3QRS1
PDB IDs		4BXO 4DAY 4DRB 4E45	4DRA 4DRB 4E44 4E45
Enriched GO Terms of Interacting Partners?		Response To Stress DNA Repair Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Cellular Protein Metabolic Process Resolution Of Meiotic Recombination Intermediates DNA Metabolic Process Replication Fork Processing Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Chromosome Separation CENP-A Containing Nucleosome Assembly Cellular Response To Stimulus DNA Recombination Histone Exchange DNA Replication-independent Nucleosome Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Reciprocal Meiotic Recombination Centromere Complex Assembly Cellular Nitrogen Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Response To Stimulus Protein Complex Assembly Reproduction ATP-dependent Chromatin Remodeling Nitrogen Compound Metabolic Process Cell Division Meiotic Chromosome Segregation Response To Radiation Meiosis I DNA-dependent DNA Replication Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleosome Assembly Chromatin Assembly Positive Regulation Of Protein Ubiquitination Collateral Sprouting In Absence Of Injury Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly PML Body Organization Meiotic Nuclear Division Positive Regulation Of Protein Complex Assembly Regulation Of Protein Kinase Activity	Cell Cycle Process Resolution Of Meiotic Recombination Intermediates Mitotic Cell Cycle Arrest Replication Fork Processing Cell Cycle Chromosome Separation Chromosome Segregation Reciprocal Meiotic Recombination Cellular Response To Drug Positive Regulation Of Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Protein Metabolic Process Meiotic Chromosome Segregation Somitogenesis Positive Regulation Of Signal Transduction Negative Regulation Of Gene Expression Positive Regulation Of SUMO Transferase Activity Negative Regulation Of Biosynthetic Process Somite Development Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Meiosis I DNA-dependent DNA Replication Cellular Response To Oxygen Levels Segmentation Cellular Response To Stress DNA Repair Negative Regulation Of Macromitophagy Positive Regulation Of Androgen Secretion Oligodendrocyte Apoptotic Process Chromatin Assembly Mitotic Cell Cycle Process Cell Cycle Arrest Chromatin Assembly Or Disassembly Negative Regulation Of Helicase Activity Negative Regulation Of Estrogen Receptor Binding Regulation Of Intrinsic Apoptotic Signaling Pathway Mitotic Cell Cycle Positive Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Meiotic Nuclear Division Response To Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Intracellular Signal Transduction DNA Packaging Cellular Macromolecule Biosynthetic Process Cellular Response To DNA Damage Stimulus Macromolecule Biosynthetic Process
Tagcloud ?		anemia arise atm deficiency encoding failure fanconi fertility germ hypogonadism includes instability maintenance males meiotic neonates overlaid partially pgcs phenotypes primordial progressive propagate propagation repair sexes testicular true	advance angiographically angiography arteriovenous auto autoantibodies autoimmunity bioinformatics camk2a carotid cd79a cerebrovascular collateral ctnnb1 custom devastating edil3 efna3 elisas fragile gps1 interpolating malformation mmd moyamoya occlusion ror1 stenosis supraclinoid
Tagcloud (Difference) ?		anemia arise atm deficiency encoding failure fanconi fertility germ hypogonadism includes instability maintenance males meiotic neonates overlaid partially pgcs phenotypes primordial progressive propagate propagation repair sexes testicular true	advance angiographically angiography arteriovenous auto autoantibodies autoimmunity bioinformatics camk2a carotid cd79a cerebrovascular collateral ctnnb1 custom devastating edil3 efna3 elisas fragile gps1 interpolating malformation mmd moyamoya occlusion ror1 stenosis supraclinoid
Tagcloud (Intersection) ?