FANCM

Gene Name		Fanconi anemia, complementation group M
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Fanconi Anaemia Nuclear Complex FANCM-MHF Complex
	Molecular Function	DNA Binding Chromatin Binding Helicase Activity Nuclease Activity Protein Binding ATP Binding
	Biological Process	Resolution Of Meiotic Recombination Intermediates DNA Repair Replication Fork Processing Nucleic Acid Phosphodiester Bond Hydrolysis
Pathways		Fanconi Anemia pathway
Drugs
Diseases
GWAS
Protein-protein Interactions		8 interactors: APITD1 APP C19orf40 ECT2 EME2 STRA13 SUMO1 TRIM27
Entrez ID		57697
HPRD ID		13876
Ensembl ID		ENSG00000187790
Uniprot IDs		B2RTQ9 Q8IYD8
PDB IDs		4BXO 4DAY 4DRB 4E45
Enriched GO Terms of Interacting Partners?		Response To Stress DNA Repair Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Cellular Protein Metabolic Process Resolution Of Meiotic Recombination Intermediates DNA Metabolic Process Replication Fork Processing Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Chromosome Separation CENP-A Containing Nucleosome Assembly Cellular Response To Stimulus DNA Recombination Histone Exchange DNA Replication-independent Nucleosome Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Reciprocal Meiotic Recombination Centromere Complex Assembly Cellular Nitrogen Compound Metabolic Process Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Cellular Component Assembly Response To Stimulus Protein Complex Assembly Reproduction ATP-dependent Chromatin Remodeling Nitrogen Compound Metabolic Process Cell Division Meiotic Chromosome Segregation Response To Radiation Meiosis I DNA-dependent DNA Replication Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Interleukin-2 Secretion Synaptic Growth At Neuromuscular Junction Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Nucleosome Assembly Chromatin Assembly Positive Regulation Of Protein Ubiquitination Collateral Sprouting In Absence Of Injury Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly PML Body Organization Meiotic Nuclear Division Positive Regulation Of Protein Complex Assembly Regulation Of Protein Kinase Activity
Tagcloud ?		anemia arise atm deficiency encoding failure fanconi fertility germ hypogonadism includes instability maintenance males meiotic neonates overlaid partially pgcs phenotypes primordial progressive propagate propagation repair sexes testicular true