ZBTB2 and MRPL11

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB2	MRPL11
Description		zinc finger and BTB domain containing 2	mitochondrial ribosomal protein L11
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Mitochondrion Mitochondrial Inner Membrane Mitochondrial Ribosome Mitochondrial Large Ribosomal Subunit Ribosome Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Binding Structural Constituent Of Ribosome Protein Binding Large Ribosomal Subunit RRNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process	Translation Mitochondrial Translation
Pathways			Mitochondrial translation initiation Mitochondrial translation elongation Mitochondrial translation elongation Mitochondrial translation termination Mitochondrial ribosome-associated quality control
Drugs
Diseases
GWAS		Appendicular lean mass ( 33097823) Chronic myeloid leukemia ( 21540461) Monocyte count ( 32888494) Refractive error ( 32231278)	Bipolar disorder ( 21926972) Hip circumference adjusted for BMI ( 34021172) Low density lipoprotein cholesterol levels ( 32154731)
Interacting Genes		25 interacting genes: CREBBP DAXX GABARAPL2 IP6K2 KAT5 LHX4 LNX1 MEOX2 MKLN1 MOS MRPL11 PICK1 PIN1 RASSF8 SP1 STAT6 SUMO1 SUMO2 SUV39H1 TENT5B TMC6 UBE2I ZBTB18 ZBTB49 ZMYND19	31 interacting genes: AGTRAP APP CAMK2A CAMK2B CAMK2D CAMK2G CCDC172 CRYAB ERCC6 FSD2 GOLGA6L9 HMBOX1 HOMEZ JAKMIP1 JAKMIP2 KRT40 MTUS2 PDCL PNMA1 SLC16A9 STX2 TAX1BP1 TFCP2 TFIP11 THAP1 VPS52 ZBTB14 ZBTB2 ZBTB8A ZNF438 ZNF526
Entrez ID		57621	65003
HPRD ID		10314	14739
Ensembl ID		ENSG00000181472	ENSG00000174547
Uniprot IDs		Q8N680	Q9Y3B7
PDB IDs			3J7Y 3J9M 5OOL 5OOM 6I9R 6NU2 6NU3 6VLZ 6VMI 6ZM5 6ZM6 6ZS9 6ZSA 6ZSB 6ZSC 6ZSD 6ZSE 6ZSG 7A5F 7A5G 7A5H 7A5I 7A5J 7A5K 7L08 7L20 7O9K 7O9M 7ODR 7ODS 7ODT 7OF0 7OF2 7OF3 7OF4 7OF5 7OF6 7OF7 7OG4 7OI6 7OI7 7OI8 7OI9 7OIA 7OIB 7OIC 7OID 7OIE 7PD3 7PO4 7QI4 7QI5 7QI6 8ANY 8K2A 8K2B 8OIR 8OIT 8PK0 8QSJ 8QU1 8QU5 8RRI 8XT0 8XT1 8XT2 8XT3
Enriched GO Terms of Interacting Partners?		Postsynaptic Cytosol Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Cellular Response To Nutrient Levels Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Transcription By RNA Polymerase II Cellular Response To Starvation Presynaptic Cytosol Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Response To Starvation Negative Regulation Of RNA Metabolic Process PML Body Small Protein Activating Enzyme Binding Protein Stabilization Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Sequence-specific DNA Binding Cellular Response To Glucose Starvation Transcription Coactivator Binding Negative Regulation Of Transcription By RNA Polymerase II Protein Sumoylation Negative Regulation Of DNA-templated Transcription Response To Nutrient Levels Negative Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Positive Regulation Of Metabolic Process Nucleoplasm Negative Regulation Of Macromolecule Metabolic Process Peptidyl-lysine Acetylation Positive Regulation Of DNA Recombination Nucleus Regulation Of Protein Stability Protein Tag Activity Regulation Of Gene Expression Negative Regulation Of Metabolic Process Cellular Response To Stress Regulation Of Macromolecule Biosynthetic Process Acetyltransferase Activity Regulation Of DNA Repair Cellular Response To Cadmium Ion SUMO Transferase Activity Transcription Factor Binding	Calcium- And Calmodulin-dependent Protein Kinase Complex Regulation Of Neuronal Synaptic Plasticity Calcium/calmodulin-dependent Protein Kinase Activity Long-term Synaptic Potentiation Positive Regulation Of Synaptic Transmission Sarcoplasmic Reticulum Endocytic Vesicle Membrane Regulation Of Synaptic Plasticity Protein Homodimerization Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Calcium Ion Transport Negative Regulation Of DNA Repair Negative Regulation Of Double-strand Break Repair Regulation Of Protein Localization To Plasma Membrane Sarcoplasmic Reticulum Membrane Negative Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Regulation Of Protein Localization To Cell Periphery Regulation Of Skeletal Muscle Adaptation Identical Protein Binding Regulation Of Protein Localization To Membrane Positive Regulation Of Cardiac Muscle Cell Apoptotic Process Neuron Projection Negative Regulation Of RNA Biosynthetic Process Regulation Of Calcium Ion Transmembrane Transport Via High Voltage-gated Calcium Channel Negative Regulation Of DNA-templated Transcription Regulation Of Metal Ion Transport Protein Binding Calmodulin Binding Regulation Of Amyloid Fibril Formation Transcription Factor Binding Angiotensin-activated Signaling Pathway Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Kinase Binding Regulation Of Monoatomic Ion Transport DNA Binding Regulation Of Transcription By RNA Polymerase II Regulation Of Long-term Neuronal Synaptic Plasticity Postsynaptic Density Microtubule Binding Amyloid-beta Complex Growth Cone Lamellipodium Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Response To Calcium Ion Negative Regulation Of Transcription By RNA Polymerase II Amylin Binding Positive Regulation Of Toll Signaling Pathway Adrenergic Receptor Binding Peptidyl-threonine Autophosphorylation
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