PDZD4 and APIP

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		PDZD4	APIP
Description		PDZ domain containing 4	APAF1 interacting protein
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cell Cortex	Cytoplasm Cytosol
	Molecular Function		Protein Binding Zinc Ion Binding Lyase Activity Identical Protein Binding Methylthioribulose 1-phosphate Dehydratase Activity Metal Ion Binding
	Biological Process		Apoptotic Process Amino Acid Biosynthetic Process Methionine Biosynthetic Process L-methionine Salvage From Methylthioadenosine Negative Regulation Of Apoptotic Process Protein Homotetramerization Pyroptotic Inflammatory Response Regulation Of ERK1 And ERK2 Cascade
Pathways			Formation of apoptosome Methionine salvage pathway Regulation of the apoptosome activity
Drugs
Diseases
GWAS			Chronic obstructive pulmonary disease-related biomarkers ( 23144326) Cystic fibrosis severity ( 21602797) Gamma glutamyl transferase levels ( 29403010 33339817) Lung disease severity in cystic fibrosis ( 26417704) Prostate-specific antigen levels ( 28139693) Systemic lupus erythematosus ( 19838195)
Interacting Genes		15 interacting genes: APIP APP ASCL4 CEP76 CTDSP1 DNMT3L DYDC1 ENKD1 GFI1B IKZF3 JRK KCTD9 MTUS2 TRAF2 TRAF3	18 interacting genes: APAF1 BAZ2B CFAP206 GORASP2 IMPDH2 LNX1 NIF3L1 NTAQ1 NUDT18 PDZD4 PPP1CC PSMA1 SDCBP SKP1 TNPO2 VIM VPS25 ZBTB25
Entrez ID		57595	51074
HPRD ID		06601	14725
Ensembl ID		ENSG00000067840	ENSG00000149089
Uniprot IDs		B3KW03 Q17RL8 Q76G19	Q96GX9
PDB IDs			4M6R
Enriched GO Terms of Interacting Partners?		Thioesterase Binding CD40 Receptor Complex
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