SIPA1L2 and AP3M1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SIPA1L2	AP3M1
Gene Name		signal-induced proliferation-associated 1 like 2	adaptor-related protein complex 3, mu 1 subunit
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Lysosome Lysosomal Membrane Golgi Apparatus Clathrin Adaptor Complex Cytoplasmic Vesicle Membrane
	Molecular Function	GTPase Activator Activity	Protein Binding Rab GTPase Binding
	Biological Process	Positive Regulation Of GTPase Activity Regulation Of Small GTPase Mediated Signal Transduction	Protein Targeting To Lysosome Anterograde Axon Cargo Transport Anterograde Synaptic Vesicle Transport
Pathways			Protein folding Chaperonin-mediated protein folding Association of TriC/CCT with target proteins during biosynthesis
Drugs
Diseases
GWAS		Immunoglobulin A ( 20694011)	Primary tooth development (number of teeth) ( 23704328) Primary tooth development (time to first tooth eruption) ( 23704328)
Protein-Protein Interactions		3 interactors: AP3M1 ORC5 TGM2	8 interactors: AGTRAP AQP4 CRMP1 RSPH14 RUFY1 SIPA1L2 TGOLN2 TRIM9
Entrez ID		57568	26985
HPRD ID		15346	16496
Ensembl ID		ENSG00000116991
Uniprot IDs		Q9P2F8	B4DRN6 Q9Y2T2
PDB IDs
Enriched GO Terms of Interacting Partners?		Isopeptide Cross-linking Via N6-(L-isoglutamyl)-L-lysine Salivary Gland Cavitation Positive Regulation Of Mitochondrial Calcium Ion Concentration Negative Regulation Of Endoplasmic Reticulum Calcium Ion Concentration Protein Targeting To Lysosome Protein Localization To Lysosome Positive Regulation Of Cytosolic Calcium Ion Concentration Involved In Phospholipase C-activating G-protein Coupled Signaling Pathway Mitochondrial Calcium Ion Homeostasis Anterograde Synaptic Vesicle Transport Protein Targeting To Vacuole Establishment Of Protein Localization To Vacuole Anterograde Axon Cargo Transport Branching Involved In Salivary Gland Morphogenesis Apoptotic Cell Clearance Endoplasmic Reticulum Calcium Ion Homeostasis DNA Replication Initiation Blood Vessel Remodeling Salivary Gland Morphogenesis Peptide Cross-linking Lysosomal Transport Salivary Gland Development Axon Cargo Transport Positive Regulation Of Smooth Muscle Cell Proliferation Exocrine System Development Phospholipase C-activating G-protein Coupled Receptor Signaling Pathway	Negative Regulation Of SNARE Complex Assembly Carbon Dioxide Transport Renal Water Absorption Renal Water Transport Angiotensin-activated Signaling Pathway Regulation Of SNARE Complex Assembly Pyrimidine Nucleobase Catabolic Process Negative Regulation Of Vesicle Fusion Hyperosmotic Salinity Response Glycerol Transport Renal Absorption Polyol Transport Regulation Of Vesicle-mediated Transport Cellular Water Homeostasis
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