KLHL42 and FAM168A

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		KLHL42	FAM168A
Gene Name		kelch-like family member 42	family with sequence similarity 168, member A
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Spindle Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding
	Biological Process	Protein Polyubiquitination Mitotic Nuclear Division Regulation Of Microtubule-based Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cell Division
Pathways
Drugs
Diseases
GWAS			Pulmonary function (interaction) ( 23284291)
Protein-Protein Interactions		15 interactors: CALCOCO2 COIL CUL3 DDI1 FAM168A RCN3 SERTAD1 SSX2IP STAM2 STXBP4 TRIM23 UBE2E3 UBQLN1 UBQLN4 USHBP1	22 interactors: C1orf94 CALCOCO2 DAB1 DAZAP2 DTX2 KLHL42 NAF1 OTUB2 OTULIN PRR20A R3HDM2 RBFOX1 RBPMS SF1 SMAP2 SNRPC SS18L1 TAX1BP1 TNIP1 UBASH3B UBE2V1 VPS37C
Entrez ID		57542	23201
HPRD ID		17237	13792
Ensembl ID		ENSG00000087448	ENSG00000054965
Uniprot IDs		B2RNT7 Q9P2K6	Q92567
PDB IDs
Enriched GO Terms of Interacting Partners?			Modulation By Symbiont Of Host I-kappaB Kinase/NF-kappaB Cascade Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Activation Of Innate Immune Response Positive Regulation Of Innate Immune Response Intracellular Receptor Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway Regulation Of Innate Immune Response Toll-like Receptor Signaling Pathway Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Defense Response Immune Response-regulating Signaling Pathway Gene Expression Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway MRNA Splice Site Selection Regulation Of RNA Metabolic Process Negative Regulation Of Viral Genome Replication Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling RNA Processing Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Protein Linear Deubiquitination Error-free Postreplication DNA Repair Negative Regulation Of ERK1 And ERK2 Cascade Spliceosomal Complex Assembly Negative Regulation Of NF-kappaB Transcription Factor Activity Regulation Of Gene Expression Positive Regulation Of Immune Response Regulation Of Inflammatory Response Regulation Of Nitrogen Compound Metabolic Process Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Cerebellum Structural Organization Ribonucleoprotein Complex Biogenesis Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Positive Regulation Of Metabolic Process RNA Splicing Regulation Of Nucleic Acid-templated Transcription Regulation Of Metabolic Process Regulation Of RNA Biosynthetic Process Cellular Protein Metabolic Process Regulation Of Phosphorylation Lateral Motor Column Neuron Migration Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Inflammatory Response Cellular Metabolic Process Innate Immune Response Interaction With Host
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