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KLHL42 and FAM168A
Number of citations of the paper that reports this interaction (PubMedID
25416956
)
56
Data Source:
BioGRID
(two hybrid)
KLHL42
FAM168A
Description
kelch like family member 42
family with sequence similarity 168 member A
Image
No pdb structure
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Spindle
Cytosol
Cytoskeleton
Cul3-RING Ubiquitin Ligase Complex
Molecular Function
Ubiquitin-protein Transferase Activity
Protein Binding
Protein Binding
Biological Process
Protein Polyubiquitination
Protein Ubiquitination
Regulation Of Microtubule-based Process
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Cell Division
Positive Regulation Of Base-excision Repair
Pathways
Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Drugs
Diseases
GWAS
Electrocardiogram morphology (amplitude at temporal datapoints) (
32916098
)
Gut microbiota (functional units) (
27694959
)
Height (
31562340
)
Osteoarthritis (hip) (
30664745
)
Refractive error (
32231278
)
Resting heart rate (
27798624
)
Type 2 diabetes (
30054458
)
Apolipoprotein A1 levels (
32203549
)
Diastolic blood pressure (
30224653
)
Heel bone mineral density (
30598549
)
Lung function (FEV1/FVC) (
30061609
)
Platelet count (
32888494
)
Pulmonary function (smoking interaction) (
23284291
)
Refractive error (
32231278
)
Waist-hip ratio (
28552196
)
Interacting Genes
35 interacting genes:
ADD1
ANKRD33
CALCOCO2
CDCA4
CKMT2
COIL
CT55
CUL3
DAZAP2
DDI1
FAM168A
INCA1
KRTAP19-4
MYOG
OIP5
OSTF1
P4HB
PFDN5
POMC
RCN3
REL
SERTAD1
SERTAD3
SSX2IP
STAM2
STXBP4
TRIM23
TRIM54
TTC23
UBE2E3
UBQLN1
UBQLN2
UBQLN4
USHBP1
VPS52
77 interacting genes:
AKT1
ALKBH4
ATXN1
ATXN1L
BOLL
C10orf55
C1orf94
CALCOCO2
CAMK2A
DAB1
DAZAP2
DCUN1D1
DTX2
EPN2
EPN3
FAM168B
FBXW5
HGS
HIP1
HR
KLHL42
KRTAP19-1
KRTAP19-5
KRTAP19-7
KRTAP3-1
KRTAP3-3
KRTAP6-2
KRTAP7-1
KRTAP8-1
LASP1
MEIS2
NAF1
NFYC
OTUB2
OTULIN
PATZ1
PEF1
PITX1
PLEKHB2
PROP1
PRR20A
PRR20B
PRR20C
PRR20D
PRR20E
PSORS1C1
R3HDM2
RBFOX1
RBPMS
RBPMS2
RHOXF2
RNF216
RPS27A
SECISBP2
SF1
SMAP2
SNRPC
SS18L1
TAX1BP1
TFAP2D
TFG
TIAL1
TNIP1
TNK1
TOLLIP
UBA52
UBAC1
UBASH3B
UBB
UBC
UBE2V1
UBQLN2
UBXN6
UBXN7
VPS37C
YOD1
YTHDF1
Entrez ID
57542
23201
HPRD ID
17237
13792
Ensembl ID
ENSG00000087448
ENSG00000054965
Uniprot IDs
B2RNT7
F5H523
Q9P2K6
Q92567
PDB IDs
Enriched GO Terms of Interacting Partners
?
Autophagosome
Polyubiquitin Modification-dependent Protein Binding
Regulation Of Protein-containing Complex Disassembly
Protein Tag Activity
Intermediate Filament
Post-translational Protein Modification
Ubiquitin Protein Ligase Binding
Protein Binding
Proteolysis Involved In Protein Catabolic Process
Protein Modification By Small Protein Conjugation
Protein Ubiquitination
Cytoplasmic Stress Granule
Modification-dependent Protein Catabolic Process
Endocytic Vesicle Membrane
Positive Regulation Of Post-translational Protein Modification
Macromolecule Catabolic Process
Autophagy
Proteolysis
Regulation Of Post-translational Protein Modification
POZ Domain Binding
Cytosol
Positive Regulation Of Protein Monoubiquitination
Identical Protein Binding
Protein Modification Process
Regulation Of Protein Monoubiquitination
Glutamate Receptor Binding
Clathrin-coated Vesicle
Ubiquitin Conjugating Enzyme Binding
RNA Stabilization
Clathrin Binding
Clathrin Vesicle Coat
Regulation Of MRNA Metabolic Process
Protein Metabolic Process
Catabolic Process
Endosome Transport Via Multivesicular Body Sorting Pathway
Macroautophagy
Negative Regulation Of RNA Catabolic Process
Cytoplasm
Positive Regulation Of Macromolecule Metabolic Process
MRNA Binding
Protein K11-linked Deubiquitination
RNA Binding
Vesicle
Cellular Response To Granulocyte Macrophage Colony-stimulating Factor Stimulus
Positive Regulation Of Translational Initiation
Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway
Multivesicular Body Sorting Pathway
Ubiquitin Binding
Proteasomal Protein Catabolic Process
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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