KLHL42 and RCN3

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
HPRD (two hybrid)

		KLHL42	RCN3
Gene Name		kelch-like family member 42	reticulocalbin 3, EF-hand calcium binding domain
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Spindle Cul3-RING Ubiquitin Ligase Complex	Endoplasmic Reticulum Lumen
	Molecular Function	Ubiquitin-protein Transferase Activity Protein Binding	Calcium Ion Binding Protein Binding
	Biological Process	Protein Polyubiquitination Mitotic Nuclear Division Regulation Of Microtubule-based Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Cell Division
Pathways
Drugs
Diseases
GWAS			Hematological and biochemical traits ( 20139978)
Protein-Protein Interactions		15 interactors: CALCOCO2 COIL CUL3 DDI1 FAM168A RCN3 SERTAD1 SSX2IP STAM2 STXBP4 TRIM23 UBE2E3 UBQLN1 UBQLN4 USHBP1	9 interactors: HID1 KLHL42 MBD3 MKNK1 PACRGL PCSK6 PRUNE2 STAT6 SUFU
Entrez ID		57542	57333
HPRD ID		17237	17962
Ensembl ID		ENSG00000087448	ENSG00000142552
Uniprot IDs		B2RNT7 Q9P2K6	Q96D15
PDB IDs
Enriched GO Terms of Interacting Partners?			Response To Brefeldin A Determination Of Left/right Symmetry Determination Of Bilateral Symmetry T-helper 1 Cell Lineage Commitment Nerve Growth Factor Production Zygotic Determination Of Anterior/posterior Axis, Embryo Nerve Growth Factor Processing Positive Regulation Of Isotype Switching To IgE Isotypes Interleukin-4-mediated Signaling Pathway Smoothened Signaling Pathway Involved In Spinal Cord Motor Neuron Cell Fate Specification Smoothened Signaling Pathway Involved In Ventral Spinal Cord Interneuron Specification Negative Regulation Of Transcription From RNA Polymerase II Promoter Smoothened Signaling Pathway Involved In Ventral Spinal Cord Patterning Methylation-dependent Chromatin Silencing T-helper Cell Lineage Commitment Negative Regulation Of Smoothened Signaling Pathway Involved In Dorsal/ventral Neural Tube Patterning T-helper 1 Cell Differentiation Negative Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process CD4-positive Or CD8-positive, Alpha-beta T Cell Lineage Commitment Cell Fate Commitment Negative Regulation Of Type 2 Immune Response Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Ventral Spinal Cord Interneuron Specification Negative Regulation Of RNA Biosynthetic Process Mammary Gland Epithelial Cell Proliferation Embryo Development Cellular Response To Reactive Nitrogen Species Spinal Cord Motor Neuron Cell Fate Specification Positive Regulation Of Isotype Switching T Cell Lineage Commitment Ventral Spinal Cord Interneuron Fate Commitment Response To Organic Substance Anterior/posterior Axis Specification, Embryo Ventral Spinal Cord Interneuron Differentiation Positive T Cell Selection T-helper 1 Type Immune Response Cytoplasmic Sequestering Of Transcription Factor T-helper Cell Differentiation Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process
Tagcloud ?			advances attached ca2 cab45 calu calumenin carboxylase chaperone concern crec cytosol ef encoded epoxide erc localized participation parts pathophysiological rcn1 rcn2 reductase reticulocalbin ryanodine sarcoplasmic sdf4 secretory splicing transporting
Tagcloud (Difference) ?			advances attached ca2 cab45 calu calumenin carboxylase chaperone concern crec cytosol ef encoded epoxide erc localized participation parts pathophysiological rcn1 rcn2 reductase reticulocalbin ryanodine sarcoplasmic sdf4 secretory splicing transporting
Tagcloud (Intersection) ?