CASKIN1 and MINK1

Number of citations of the paper that reports this interaction (PMID 15032605)
1

Data Source:
HPRD (two hybrid)

		CASKIN1	MINK1
Gene Name		CASK interacting protein 1	misshapen-like kinase 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm	Cytoplasm Golgi Apparatus Cytosol Postsynaptic Density Cell Junction Axon Dendrite Postsynaptic Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding	Protein Kinase Activity Protein Serine/threonine Kinase Activity Receptor Signaling Protein Serine/threonine Kinase Activity Small GTPase Regulator Activity Protein Binding ATP Binding
	Biological Process	Signal Transduction	Regulation Of Cell-matrix Adhesion Protein Phosphorylation Response To Stress JNK Cascade Synaptic Transmission Multicellular Organismal Development Regulation Of Cell-cell Adhesion Microvillus Assembly Regulation Of Cell Migration Actin Cytoskeleton Reorganization Intracellular Signal Transduction Negative Thymic T Cell Selection Positive Regulation Of JNK Cascade Protein Autophosphorylation Dendrite Morphogenesis Regulation Of Catalytic Activity Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity
Pathways			Oxidative Stress Induced Senescence Cellular Senescence
Drugs
Diseases
GWAS		Height ( 20881960)
Protein-Protein Interactions		2 interactors: CASK MINK1	14 interactors: ABI1 ACTA2 CALM3 CASKIN1 KIFAP3 MAP1B NCK1 NEDD4L NEFM PKP4 SPTBN2 TUBA1B YWHAB YWHAZ
Entrez ID		57524	50488
HPRD ID		10809	11366
Ensembl ID		ENSG00000167971	ENSG00000141503
Uniprot IDs		Q8WXD9	Q8N4C8
PDB IDs		3SEI 3SEN
Enriched GO Terms of Interacting Partners?		Regulation Of Cell-matrix Adhesion Regulation Of Cell-substrate Adhesion Regulation Of Ion Transmembrane Transport Regulation Of Cell Adhesion Regulation Of Ion Transport Negative Regulation Of Keratinocyte Proliferation Negative Thymic T Cell Selection Positive Regulation Of Calcium Ion Import Negative T Cell Selection Regulation Of Alpha-amino-3-hydroxy-5-methyl-4-isoxazole Propionate Selective Glutamate Receptor Activity Thymic T Cell Selection Regulation Of Keratinocyte Proliferation Regulation Of Calcium Ion Import Cell Adhesion Calcium Ion Import Negative Regulation Of Cell-matrix Adhesion Protein Phosphorylation T Cell Selection Negative Regulation Of Cell-substrate Adhesion Nucleotide Phosphorylation Lactation Actin Cytoskeleton Reorganization Negative Regulation Of Wound Healing T Cell Differentiation In Thymus Phosphorylation Positive Regulation Of Ion Transmembrane Transport Dendrite Morphogenesis JNK Cascade Protein Stabilization Positive Regulation Of Calcium Ion Transport Body Fluid Secretion Negative Regulation Of Cellular Response To Growth Factor Stimulus Regulation Of Receptor Activity Stress-activated MAPK Cascade Stress-activated Protein Kinase Signaling Cascade Positive Regulation Of JNK Cascade Negative Regulation Of Epithelial Cell Proliferation Regulation Of Wound Healing Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Regulation Of Protein Stability Dendrite Development Positive Regulation Of Cellular Metabolic Process Regulation Of Ion Transmembrane Transporter Activity Regulation Of Transmembrane Transporter Activity T Cell Differentiation Regulation Of JNK Cascade Mammary Gland Development Phosphate-containing Compound Metabolic Process Regulation Of Cellular Response To Growth Factor Stimulus	Vascular Endothelial Growth Factor Receptor Signaling Pathway Cytoskeleton-dependent Intracellular Transport Cellular Component Assembly Transport Movement Of Cell Or Subcellular Component Fc Receptor Signaling Pathway Regulation Of Cellular Component Size Regulation Of Cellular Component Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Establishment Of Localization In Cell Microtubule-based Transport Negative Regulation Of Transport Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway Cell Projection Morphogenesis Cell Part Morphogenesis Regulation Of Intracellular Transport Immune System Process Enzyme Linked Receptor Protein Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Intracellular Transport Organelle Organization Positive Regulation Of Cation Channel Activity Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Cellular Localization Positive Regulation Of Apoptotic Signaling Pathway Axonogenesis Regulation Of Cellular Localization Cell Morphogenesis Negative Regulation Of Transporter Activity Axon Development Cell Morphogenesis Involved In Neuron Differentiation Cytoskeleton Organization Cell Development Negative Regulation Of Ion Transmembrane Transport Cell Projection Organization Lamellipodium Organization Positive Regulation Of Ion Transmembrane Transporter Activity Neuron Projection Morphogenesis Organelle Transport Along Microtubule Negative Regulation Of Transmembrane Transport Positive Regulation Of Protein Metabolic Process Positive Regulation Of Transporter Activity Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Cytokinesis Positive Regulation Of Mitochondrion Organization Immune Response Positive Regulation Of Cap-dependent Translational Initiation Positive Regulation Of Cap-independent Translational Initiation Positive Regulation Of Calcium-dependent Cell-cell Adhesion
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