XPO5 and ILF3

Number of citations of the paper that reports this interaction (PMID 11777942)
49

Data Source:
BioGRID (two hybrid, pull down, affinity chromatography technology, pull down)
HPRD (two hybrid, in vitro, in vivo)

		XPO5	ILF3
Gene Name		exportin 5	interleukin enhancer binding factor 3, 90kDa
Image
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Membrane Ribonucleoprotein Complex
	Molecular Function	TRNA Binding RNA Binding Protein Binding Ran GTPase Binding Protein Transporter Activity Poly(A) RNA Binding	DNA Binding RNA Binding Double-stranded RNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Protein Export From Nucleus Gene Expression Gene Silencing By RNA	Transcription, DNA-templated Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Defense Response To Virus
Pathways		Regulatory RNA pathways MicroRNA (miRNA) biogenesis
Drugs
Diseases
GWAS			Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: EEF1A1 FADD ILF3 NUP153 NUP214 RAN SMAD4 ZNF346	26 interactors: DHX9 EIF2AK2 ERG FUS GDF9 HNRNPH2 IL7R KRTAP4-12 LNX1 MAGEA11 MDFI NDRG1 PLSCR1 PRMT1 RBM5 RBPMS RNF113A SF1 SF3B4 SMN1 SNRPC TRIP6 XAB2 XPO5 ZNF346 ZNF830
Entrez ID		57510	3609
HPRD ID		06385	04420
Ensembl ID		ENSG00000124571	ENSG00000129351
Uniprot IDs		Q9HAV4	Q12906
PDB IDs		3A6P	2L33 3P1X
Enriched GO Terms of Interacting Partners?		Nuclear Import Viral Process Viral Life Cycle Intracellular Transport Of Virus Mitotic Nuclear Envelope Disassembly Nucleocytoplasmic Transport Protein Export From Nucleus Nuclear Transport Nuclear Envelope Disassembly Gene Expression Nuclear Envelope Organization Glucose Transport Hexose Transport Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Viral Transcription RNA Biosynthetic Process Regulation Of Glucose Transport Positive Regulation Of Transcription, DNA-templated Nephrogenic Mesenchyme Morphogenesis Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Negative Regulation Of RNA Export From Nucleus Motor Neuron Apoptotic Process Viral Penetration Into Host Nucleus Nuclear Export MRNA Transport Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Positive Regulation Of Macromolecule Biosynthetic Process RNA Transport Positive Regulation Of Gene Expression Ribosomal Small Subunit Export From Nucleus Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis TRAIL-activated Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process RNA Localization Positive Regulation Of Cellular Biosynthetic Process Protein Import Mitotic Cell Cycle Process Cytoplasmic Transport Defense Response To Virus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Localization To Nucleus Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process	MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions RNA Splicing RNA Processing MRNA Processing MRNA Metabolic Process Gene Expression RNA Metabolic Process Spliceosomal Complex Assembly Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Ribonucleoprotein Complex Assembly Regulation Of Gene Expression Regulation Of Female Gonad Development Ribonucleoprotein Complex Biogenesis Regulation Of Hematopoietic Progenitor Cell Differentiation Cellular Metabolic Process Regulation Of Protein Import Into Nucleus Spliceosomal SnRNP Assembly Regulation Of Nitrogen Compound Metabolic Process MRNA Splice Site Selection Negative Regulation Of Viral Genome Replication Regulation Of Protein Localization To Nucleus Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Evasion Or Tolerance By Virus Of Host Immune Response Negative Regulation Of Potassium Ion Export Regulation Of Nucleocytoplasmic Transport In Utero Embryonic Development Regulation Of RNA Metabolic Process Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulation Of MRNA Splicing, Via Spliceosome Regulation Of Intracellular Protein Transport Regulation Of Heart Rate By Hormone Interleukin-7-mediated Signaling Pathway Regulation Of Hematopoietic Stem Cell Differentiation Oocyte Growth Regulation Of Viral Genome Replication Negative Regulation Of Viral Process Cellular Response To Stress Cellular Macromolecular Complex Assembly Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Intestinal Epithelial Structure Maintenance Evasion Or Tolerance Of Host Defenses By Virus Regulation Of Metabolic Process Regulation Of MRNA Processing Regulation Of Transcription Factor Import Into Nucleus Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation
Tagcloud ?			acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored
Tagcloud (Difference) ?			acting analogues axis cll cytotoxicity dca dichloroacetate emphasize exhibits harboring hl indeed invariably knocking leukemic lymphocytic maver mec mediating merits options p21 p53mutated p53null p53wild proteomic purine sirnas underscored
Tagcloud (Intersection) ?