XPO5 and ILF3

Number of citations of the paper that reports this interaction (PubMedID 11777942)
42

Data Source:
BioGRID (proximity labelling technology, two hybrid, pull down, affinity chromatography technology, pull down)
HPRD (two hybrid, in vivo, in vitro)

		XPO5	ILF3
Description		exportin 5	interleukin enhancer binding factor 3
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol RISC Complex RNA Nuclear Export Complex	Extracellular Region Nucleus Nucleoplasm Nucleolus Cytoplasm Mitochondrion Cytosol Membrane Ribonucleoprotein Complex
	Molecular Function	TRNA Binding RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding Small GTPase Binding Pre-miRNA Binding RISC Complex Binding	Virus Receptor Activity DNA Binding RNA Binding Double-stranded RNA Binding Single-stranded RNA Binding Protein Binding MRNA 3'-UTR AU-rich Region Binding
	Biological Process	RNA Export From Nucleus Protein Export From Nucleus Intracellular Protein Transport MiRNA Metabolic Process Protein Transport Regulatory NcRNA-mediated Gene Silencing Pre-miRNA Export From Nucleus	Protein Phosphorylation Negative Regulation Of Translation Negative Regulation Of Viral Genome Replication Negative Regulation Of DNA-templated Transcription Positive Regulation Of DNA-templated Transcription Symbiont Entry Into Host Cell Defense Response To Virus Spliceosome-depend Formation Of Circular RNA
Pathways		MicroRNA (miRNA) biogenesis	Regulation of CDH11 gene transcription Regulation of CDH11 gene transcription PKR-mediated signaling
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Platelet count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)	Bipolar disorder ( 31043756) Chronotype ( 30696823) Height ( 25282103 25429064) Obesity-related traits ( 23251661) Psoriasis ( 23143594 25574825 25903422) Psoriasis vulgaris ( 26626624) Rheumatoid arthritis ( 30423114) Systemic lupus erythematosus ( 28714469)
Interacting Genes		10 interacting genes: CEBPA EEF1A1 FADD ILF3 NUP153 NUP214 RAN SMAD4 SUMO2 ZNF346	44 interacting genes: CEBPA DHX9 DUX4 EIF2AK2 EP300 ERBB2 ERG ESR1 FUS GDF9 HNRNPH2 IL7R IRF3 IRF9 KRTAP4-12 LINC00624 LNX1 MAGEA11 MAPK1 MDFI NDRG1 OGT PLSCR1 PRMT1 PRMT5 PSMA3 PTEN RBM5 RBPMS SF1 SF3B4 SMN1 SPOP TRIM55 TRIM63 TRIP6 UBC USP7 VPS37C XAB2 XPO5 YWHAH ZNF346 ZNF830
Entrez ID		57510	3609
HPRD ID		06385	04420
Ensembl ID		ENSG00000124571	ENSG00000129351
Uniprot IDs		Q9HAV4	Q12906
PDB IDs		3A6P 5YU6 5YU7	2L33 3P1X 7RJM 7RJQ
Enriched GO Terms of Interacting Partners?		Nucleolus Protein-containing Complex Binding Regulation Of Protein Catabolic Process Interleukin-6-mediated Signaling Pathway RNA Export From Nucleus Nuclear Export Signal Receptor Activity Nuclear Export Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Protein Import Into Nucleus Nuclear Pore Regulation Of Protein Metabolic Process RNA Transport Structural Constituent Of Nuclear Pore Nuclear Localization Sequence Binding Protein Localization To Nucleus Protein Export From Nucleus Positive Regulation Of Proteolysis Nucleobase-containing Compound Transport Nucleoplasm Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Regulation Of Intracellular Transport Gland Development RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Cytoplasmic Side Of Nuclear Pore Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Protein-containing Complex Double-stranded RNA Binding Establishment Of Protein Localization To Organelle Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleus Regulation Of Proteolysis Response To Vitamin B2 C/EBP Complex RNA Binding Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Death-inducing Signaling Complex Assembly Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription	Nucleoplasm Nucleus Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Identical Protein Binding RNA Splicing Rhythmic Process Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Protein-RNA Complex Assembly Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Biosynthetic Process Regulation Of Gene Expression Cytosol Regulation Of Macromolecule Biosynthetic Process Intracellular Signal Transduction Cytoplasm Positive Regulation Of RNA Metabolic Process RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Spliceosomal Complex Assembly Protein Modification Process Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Nucleic Acid Binding Regulation Of Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions DNA-templated Transcription Termination RNA Binding Nucleic Acid Metabolic Process TORC1 Signaling Regulation Of Metabolic Process Positive Regulation Of Macromolecule Metabolic Process Response To Stress Positive Regulation Of Metabolic Process Positive Regulation Of Gene Expression Regulation Of Cell Population Proliferation Macromolecule Biosynthetic Process Cellular Component Assembly RNA Processing Cellular Response To Nutrient Levels Protein-containing Complex Assembly RISC Complex Binding Histone H4R3 Methyltransferase Activity Peptidyl-arginine Methylation TOR Signaling Chromatin DNA Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process
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