XPO5 and ZNF346

Number of citations of the paper that reports this interaction (PMID 15254228)
20

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		XPO5	ZNF346
Gene Name		exportin 5	zinc finger protein 346
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nucleus Nucleoplasm Nucleolus Cytoplasm
	Molecular Function	TRNA Binding RNA Binding Protein Binding Ran GTPase Binding Protein Transporter Activity Poly(A) RNA Binding	Double-stranded RNA Binding Protein Binding Zinc Ion Binding Enzyme Binding Poly(A) RNA Binding
	Biological Process	Protein Export From Nucleus Gene Expression Gene Silencing By RNA	Positive Regulation Of Apoptotic Process
Pathways		Regulatory RNA pathways MicroRNA (miRNA) biogenesis
Drugs
Diseases
GWAS
Protein-Protein Interactions		8 interactors: EEF1A1 FADD ILF3 NUP153 NUP214 RAN SMAD4 ZNF346	5 interactors: ANKHD1 EIF2AK2 ILF3 TARBP2 XPO5
Entrez ID		57510	23567
HPRD ID		06385	05606
Ensembl ID		ENSG00000124571	ENSG00000113761
Uniprot IDs		Q9HAV4	B7Z367 B7Z4J8 D6RJ07 Q9UL40
PDB IDs		3A6P
Enriched GO Terms of Interacting Partners?		Nuclear Import Viral Process Viral Life Cycle Intracellular Transport Of Virus Mitotic Nuclear Envelope Disassembly Nucleocytoplasmic Transport Protein Export From Nucleus Nuclear Transport Nuclear Envelope Disassembly Gene Expression Nuclear Envelope Organization Glucose Transport Hexose Transport Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Viral Transcription RNA Biosynthetic Process Regulation Of Glucose Transport Positive Regulation Of Transcription, DNA-templated Nephrogenic Mesenchyme Morphogenesis Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Negative Regulation Of RNA Export From Nucleus Motor Neuron Apoptotic Process Viral Penetration Into Host Nucleus Nuclear Export MRNA Transport Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Positive Regulation Of Macromolecule Biosynthetic Process RNA Transport Positive Regulation Of Gene Expression Ribosomal Small Subunit Export From Nucleus Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis TRAIL-activated Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process RNA Localization Positive Regulation Of Cellular Biosynthetic Process Protein Import Mitotic Cell Cycle Process Cytoplasmic Transport Defense Response To Virus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Localization To Nucleus Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process	Regulation Of Viral Genome Replication Regulation Of Viral Process Regulation Of Translation Negative Regulation Of Defense Response To Virus Negative Regulation Of Gene Expression Negative Regulation Of Viral Genome Replication Posttranscriptional Regulation Of Gene Expression Gene Silencing By RNA Negative Regulation Of Viral Process Regulation Of Defense Response To Virus Negative Regulation Of Translation Gene Silencing Negative Regulation Of Cellular Protein Metabolic Process Evasion Or Tolerance By Virus Of Host Immune Response Negative Regulation Of Protein Metabolic Process Defense Response To Virus Regulation Of Hematopoietic Stem Cell Differentiation MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Gene Expression Evasion Or Tolerance Of Host Defenses By Virus Targeting Of MRNA For Destruction Involved In RNA Interference Regulation Of Translational Initiation By EIF2 Alpha Phosphorylation Response To Virus Regulation Of Hematopoietic Stem Cell Proliferation Production Of SiRNA Involved In RNA Interference Response To Host Immune Response RNA Interference Regulation Of NLRP3 Inflammasome Complex Assembly Negative Regulation Of Immune System Process Pre-miRNA Processing Negative Regulation Of Defense Response To Virus By Host Regulation Of Translational Initiation In Response To Stress Regulation Of Gene Expression Negative Regulation Of Osteoblast Proliferation Regulation Of Cellular Protein Metabolic Process Modulation By Virus Of Host Process Production Of MiRNAs Involved In Gene Silencing By MiRNA Negative Regulation Of Cellular Metabolic Process Regulation Of Translation In Response To Stress Response To Interferon-alpha Regulation Of Protein Metabolic Process Positive Regulation Of Viral Genome Replication Modulation By Virus Of Host Morphology Or Physiology Regulation Of Osteoblast Proliferation Regulation Of Defense Response To Virus By Virus Gene Silencing By MiRNA Regulation Of Hematopoietic Progenitor Cell Differentiation Regulation Of Defense Response To Virus By Host Cellular Response To DsRNA Response To Other Organism
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