XPO5

Description		exportin 5
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol RISC Complex RNA Nuclear Export Complex
	Molecular Function	TRNA Binding RNA Binding MRNA Binding Nuclear Export Signal Receptor Activity Protein Binding Small GTPase Binding Pre-miRNA Binding RISC Complex Binding
	Biological Process	RNA Export From Nucleus Protein Export From Nucleus Intracellular Protein Transport MiRNA Metabolic Process Protein Transport Regulatory NcRNA-mediated Gene Silencing Pre-miRNA Export From Nucleus
Pathways		MicroRNA (miRNA) biogenesis
Drugs
Diseases
GWAS		Hemoglobin levels ( 32327693) Platelet count ( 32888494) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		10 interacting genes: CEBPA EEF1A1 FADD ILF3 NUP153 NUP214 RAN SMAD4 SUMO2 ZNF346
Entrez ID		57510
HPRD ID		06385
Ensembl ID		ENSG00000124571
Uniprot IDs		Q9HAV4
PDB IDs		3A6P 5YU6 5YU7
Enriched GO Terms of Interacting Partners?		Nucleolus Protein-containing Complex Binding Regulation Of Protein Catabolic Process Interleukin-6-mediated Signaling Pathway RNA Export From Nucleus Nuclear Export Signal Receptor Activity Nuclear Export Regulation Of Nucleocytoplasmic Transport Import Into Nucleus Protein Import Into Nucleus Nuclear Pore Regulation Of Protein Metabolic Process RNA Transport Structural Constituent Of Nuclear Pore Nuclear Localization Sequence Binding Protein Localization To Nucleus Protein Export From Nucleus Positive Regulation Of Proteolysis Nucleobase-containing Compound Transport Nucleoplasm Nuclear Envelope Nuclear Transport Nucleocytoplasmic Transport Regulation Of Intracellular Transport Gland Development RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Negative Regulation Of Cardiac Myofibril Assembly Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Female Gonad Morphogenesis Cytoplasmic Side Of Nuclear Pore Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Protein-containing Complex Double-stranded RNA Binding Establishment Of Protein Localization To Organelle Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nucleus Regulation Of Proteolysis Response To Vitamin B2 C/EBP Complex RNA Binding Gonad Morphogenesis Nephrogenic Mesenchyme Morphogenesis RNA Nuclear Export Complex SnRNA Import Into Nucleus Pre-miRNA Export From Nucleus Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Death-inducing Signaling Complex Assembly Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription
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