XPO5 and NUP153

Number of citations of the paper that reports this interaction (PMID 11777942)
49

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		XPO5	NUP153
Gene Name		exportin 5	nucleoporin 153kDa
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Gene Ontology Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol	Nuclear Pore Nucleoplasm Nucleolus Cytoplasm Nuclear Membrane Nuclear Periphery Nuclear Inclusion Body Nuclear Pore Nuclear Basket
	Molecular Function	TRNA Binding RNA Binding Protein Binding Ran GTPase Binding Protein Transporter Activity Poly(A) RNA Binding	DNA Binding Transporter Activity Nucleocytoplasmic Transporter Activity Protein Binding Zinc Ion Binding Structural Constituent Of Nuclear Pore Identical Protein Binding Protein Anchor
	Biological Process	Protein Export From Nucleus Gene Expression Gene Silencing By RNA	Mitotic Cell Cycle Carbohydrate Metabolic Process Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Protein Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Viral Entry Into Host Cell Negative Regulation Of RNA Export From Nucleus MRNA Transport Nuclear Pore Complex Assembly Transmembrane Transport Viral Penetration Into Host Nucleus
Pathways		Regulatory RNA pathways MicroRNA (miRNA) biogenesis	Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS			Height ( 18391951) Obesity-related traits ( 23251661)
Protein-Protein Interactions		8 interactors: EEF1A1 FADD ILF3 NUP153 NUP214 RAN SMAD4 ZNF346	24 interactors: APC BRCA1 IPO5 KPNA2 KPNB1 MAPK1 MAPK14 MAPK3 NFX1 NUP62 NUTF2 NXF1 NXF2 RAN SENP2 SMAD2 SMAD3 TNPO1 TPR TRN-GTT2-1 XPO1 XPO5 XPO7 XPOT
Entrez ID		57510	9972
HPRD ID		06385	04899
Ensembl ID		ENSG00000124571	ENSG00000124789
Uniprot IDs		Q9HAV4	B4DIK2 F6QR24 P49790 Q4LE47 Q7Z743
PDB IDs		3A6P	2EBQ 2EBR 2EBV 2GQE
Enriched GO Terms of Interacting Partners?		Nuclear Import Viral Process Viral Life Cycle Intracellular Transport Of Virus Mitotic Nuclear Envelope Disassembly Nucleocytoplasmic Transport Protein Export From Nucleus Nuclear Transport Nuclear Envelope Disassembly Gene Expression Nuclear Envelope Organization Glucose Transport Hexose Transport Positive Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of Cell Proliferation Involved In Heart Valve Morphogenesis Viral Transcription RNA Biosynthetic Process Regulation Of Glucose Transport Positive Regulation Of Transcription, DNA-templated Nephrogenic Mesenchyme Morphogenesis Regulation Of CD8-positive, Alpha-beta Cytotoxic T Cell Extravasation Positive Regulation Of CD8-positive, Alpha-beta T Cell Extravasation Negative Regulation Of RNA Export From Nucleus Motor Neuron Apoptotic Process Viral Penetration Into Host Nucleus Nuclear Export MRNA Transport Protein Import Into Nucleus Nucleus Organization Carbohydrate Transport Positive Regulation Of Macromolecule Biosynthetic Process RNA Transport Positive Regulation Of Gene Expression Ribosomal Small Subunit Export From Nucleus Nephrogenic Mesenchyme Development Metanephric Mesenchyme Morphogenesis TRAIL-activated Apoptotic Signaling Pathway Nucleobase-containing Compound Metabolic Process RNA Localization Positive Regulation Of Cellular Biosynthetic Process Protein Import Mitotic Cell Cycle Process Cytoplasmic Transport Defense Response To Virus Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Protein Localization To Nucleus Mitotic Cell Cycle Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process	Nucleocytoplasmic Transport Nuclear Transport Cytoplasmic Transport Viral Process Nuclear Export Protein Transport Establishment Of Protein Localization Intracellular Transport RNA Transport Establishment Of Localization In Cell RNA Localization Protein Localization To Nucleus Intracellular Protein Transport Protein Localization Protein Import Into Nucleus Nuclear Import MRNA Transport Cellular Localization Protein Import Protein Export From Nucleus Transport Cellular Protein Localization Protein Localization To Organelle Establishment Of Protein Localization To Organelle Cellular Response To Organic Substance Protein Targeting Regulation Of Intracellular Transport Cell Cycle NLS-bearing Protein Import Into Nucleus Regulation Of Cytoskeleton Organization Gene Expression RNA Export From Nucleus Response To DsRNA Response To Organic Substance Cellular Response To Cytokine Stimulus MAPK Import Into Nucleus Viral Life Cycle Response To Growth Factor Regulation Of Nucleocytoplasmic Transport Positive Regulation Of Protein Import Into Nucleus Positive Regulation Of Transcription, DNA-templated Intracellular Transport Of Virus Positive Regulation Of Protein Localization To Nucleus Positive Regulation Of Nucleocytoplasmic Transport Ribosomal Small Subunit Export From Nucleus Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Cellular Localization Response To Epidermal Growth Factor Response To Cytokine Regulation Of Intracellular Protein Transport
Tagcloud ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup214 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Difference) ?			acted bona breakpoints chimeras deregulate fg fide functioned gly heterodimerization hox hoxa9 nih nucleoporin nucleoporins nup214 nup98 oncogenesis oncoproteins pbx phe physically recruit repeat repeats segments transactivation transactivators vp16
Tagcloud (Intersection) ?