ESYT2 and SLC2A4

Number of citations of the paper that reports this interaction (PMID 16396496)
24

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		ESYT2	SLC2A4
Gene Name		extended synaptotagmin-like protein 2	solute carrier family 2 (facilitated glucose transporter), member 4
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Integral Component Of Plasma Membrane Membrane Intrinsic Component Of Endoplasmic Reticulum Membrane Extrinsic Component Of Cytoplasmic Side Of Plasma Membrane Organelle Membrane Contact Site	Multivesicular Body Cytosol Plasma Membrane Integral Component Of Plasma Membrane Coated Pit External Side Of Plasma Membrane Endomembrane System Vesicle Membrane Membrane Clathrin-coated Vesicle Trans-Golgi Network Transport Vesicle T-tubule Insulin-responsive Compartment Membrane Raft Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Phosphatidylethanolamine Binding Phosphatidylcholine Binding Phosphatidylinositol Binding Identical Protein Binding	Glucose Transmembrane Transporter Activity Protein Binding D-glucose Transmembrane Transporter Activity
	Biological Process	Lipid Transport Endocytosis	Carbohydrate Metabolic Process Hexose Transport Pathogenesis Amylopectin Biosynthetic Process Glucose Transport Cellular Response To Insulin Stimulus Glucose Homeostasis Small Molecule Metabolic Process Response To Ethanol Glucose Import Brown Fat Cell Differentiation Transmembrane Transport Membrane Organization Cellular Response To Hypoxia Cellular Response To Osmotic Stress
Pathways			Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds Translocation of GLUT4 to the plasma membrane SLC-mediated transmembrane transport Hexose transport Myoclonic epilepsy of Lafora Transcriptional regulation of white adipocyte differentiation Facilitative Na+-independent glucose transporters Glycogen storage diseases Glucose transport Metabolism of carbohydrates
Drugs
Diseases
GWAS			Birth weight ( 23202124) Metabolite levels ( 22286219)
Protein-Protein Interactions		1 interactors: SLC2A4	38 interactors: ACOX1 ACTN1 ACTN4 AKT2 ARF3 ARFIP1 BSG C1QTNF5 CCDC116 CFL1 CTSD DAXX DLD EHD2 ESYT2 FAR1 FKBP10 GAPDH HADH HK2 HSP90AA1 IDH2 KLHL41 LNPEP MAP1S MVP P3H1 P3H4 PDIA6 PRKAR1A PSMD7 RAB7A SERPINH1 SRFBP1 STRN3 UBA52 UBE2I UBE2N
Entrez ID		57488	6517
HPRD ID		13053	00688
Ensembl ID		ENSG00000117868	ENSG00000181856
Uniprot IDs		A0FGR8	P14672 Q05BQ3
PDB IDs		2DMG
Enriched GO Terms of Interacting Partners?		Amylopectin Biosynthetic Process Glucose Import Hexose Transmembrane Transport Cellular Response To Osmotic Stress Brown Fat Cell Differentiation Carbohydrate Transmembrane Transport Glucose Transport Hexose Transport Response To Osmotic Stress Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Carbohydrate Transport Fat Cell Differentiation Response To Ethanol Glucose Homeostasis Pathogenesis Cellular Response To Insulin Stimulus Response To Insulin Response To Hypoxia Cellular Response To Peptide Hormone Stimulus Cellular Response To Peptide Response To Peptide Hormone Cellular Response To Organonitrogen Compound Response To Peptide	Generation Of Precursor Metabolites And Energy Catabolic Process Protein Localization To Tight Junction Protein Transport Establishment Of Protein Localization Protein Localization Small Molecule Metabolic Process Organelle Organization Positive Regulation Of Transferase Activity Monocarboxylic Acid Metabolic Process Regulation Of Body Fluid Levels Antigen Processing And Presentation Of Peptide Antigen Protein Targeting Blood Coagulation Hemostasis Pyruvate Metabolic Process Intracellular Protein Transport Oxidation-reduction Process Response To Stress Protein Localization To Cell Junction Glucose Metabolic Process Antigen Processing And Presentation Regulation Of Cellular Protein Metabolic Process Energy Derivation By Oxidation Of Organic Compounds Establishment Of Localization In Cell Protein Polyubiquitination Response To Stimulus Cellular Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Response To Organic Substance Cytoskeleton Organization Protein Localization To Membrane Platelet Degranulation Immune System Process Vesicle-mediated Transport Protein Ubiquitination Regulation Of Protein Metabolic Process Positive Regulation Of Ubiquitin-protein Transferase Activity Extracellular Matrix Organization Extracellular Structure Organization Collagen Metabolic Process Membrane Organization Actin Cytoskeleton Organization Positive Regulation Of Ligase Activity Intracellular Receptor Signaling Pathway Transport Wound Healing Multicellular Organismal Macromolecule Metabolic Process Protein Metabolic Process Regulation Of Protein Ubiquitination
Tagcloud ?		7q36 7qter affymetrix arise asymptomatic boy condensin delay deletion deletions dysmorphism encompassing father grandfather harbored heterozygosity inherited mcph1 microcephaly mother ncapg2 novo paternal prenatal psychomotor retardation snp vipr2 wdr60	atp1a2 atp1b2 beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc5a1 washings
Tagcloud (Difference) ?		7q36 7qter affymetrix arise asymptomatic boy condensin delay deletion deletions dysmorphism encompassing father grandfather harbored heterozygosity inherited mcph1 microcephaly mother ncapg2 novo paternal prenatal psychomotor retardation snp vipr2 wdr60	atp1a2 atp1b2 beef corpus cows diestrus follicle glandular gonadotropin lcl lf luteum manipulated nelore ovulation p4 periovulatory pof preovulatory proestrus receptivity slaughtered slc5a1 washings
Tagcloud (Intersection) ?