ESYT2

Description		extended synaptotagmin 2
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GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane Organelle Membrane Contact Site Endoplasmic Reticulum-plasma Membrane Contact Site
	Molecular Function	Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding Lipid Binding Phosphatidylethanolamine Binding Phosphatidylcholine Binding Phosphatidylinositol Binding Identical Protein Binding Cadherin Binding Metal Ion Binding
	Biological Process	Lipid Transport Endocytosis Endoplasmic Reticulum-plasma Membrane Tethering
Pathways		Glycosphingolipid transport
Drugs
Diseases
GWAS		Hearing loss in noise exposure ( 33242228) Mean platelet volume ( 27863252 32888494) Mild influenza (H1N1) infection ( 26379185) Mosaic loss of chromosome Y (Y chromosome dosage) ( 31624269) Platelet count ( 32888494) Refractive error ( 32231278)
Interacting Genes		1 interacting genes: SLC2A4
Entrez ID		57488
HPRD ID		13053
Ensembl ID		ENSG00000117868
Uniprot IDs		A0A499FIX8 A0FGR8 H7BXI1
PDB IDs		2DMG 4NPJ 4NPK 4P42
Enriched GO Terms of Interacting Partners?		Amylopectin Biosynthetic Process D-glucose Uniporter Activity Regulation Of Synaptic Vesicle Budding From Presynaptic Endocytic Zone Membrane Positive Regulation Of Brain-derived Neurotrophic Factor Receptor Signaling Pathway White Fat Cell Proliferation Insulin-responsive Compartment Glucose Import In Response To Insulin Stimulus Dehydroascorbic Acid Transport Fat Cell Proliferation D-glucose Transmembrane Transporter Activity Short-term Memory Trans-Golgi Network Transport Vesicle D-glucose Import Brown Fat Cell Differentiation D-glucose Transmembrane Transport Long-term Memory Hexose Transmembrane Transport Vesicle Membrane Cellular Response To Osmotic Stress Carbohydrate Transport Vitamin Transport Carbohydrate Transmembrane Transport T-tubule Multivesicular Body Sarcoplasmic Reticulum Response To Osmotic Stress Clathrin-coated Vesicle Transport Across Blood-brain Barrier Clathrin-coated Pit Cellular Response To Insulin Stimulus Cellular Response To Tumor Necrosis Factor Sarcolemma Response To Ethanol Response To Tumor Necrosis Factor Memory Fat Cell Differentiation Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Cellular Response To Oxygen Levels Cellular Response To Peptide Hormone Stimulus Vesicle Cytoplasmic Vesicle Membrane Response To Insulin Transmembrane Transporter Activity Trans-Golgi Network Carbohydrate Homeostasis Glucose Homeostasis Membrane Raft Presynapse Learning Or Memory
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