SLC38A7 and TSPAN8

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC38A7	TSPAN8
Description		solute carrier family 38 member 7	tetraspanin 8
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane Axon Cell Projection Neuronal Cell Body	Plasma Membrane Cell Surface Membrane Extracellular Exosome
	Molecular Function	Protein Binding L-asparagine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity	Integrin Binding Protein Binding
	Biological Process	Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Amino Acid Transport Asparagine Transport Glutamine Transport	Spermatogenesis Regulation Of Gene Expression Negative Regulation Of Blood Coagulation
Pathways
Drugs
Diseases
GWAS		HDL cholesterol levels in HIV infection ( 33109212) Plasma anastrozole concentration in anastrozole-treated estrogen receptor positive breast cancer ( 30648747) QT interval ( 19305408) Schizophrenia ( 25056061 29483656) Suicide attempt severity in mood disorders ( 33783297)	Asthma ( 34103634 32296059) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433) Medication use (adrenergics, inhalants) ( 31015401) Monobrow ( 27182965) Post bronchodilator FEV1/FVC ratio ( 26634245) Refractive error ( 32231278) Type 2 diabetes ( 30054458 32499647 30297969 18372903 29358691 28869590 22885922 20581827) Upper eyelid sagging severity ( 24869959)
Interacting Genes		59 interacting genes: ACBD5 AMIGO1 APH1A AQP2 AQP6 AQP9 ARL13B BTNL9 CFTR CLCN7 CLDN7 CLEC10A CPLX4 CREB3L3 CYB561 CYB5R3 EDA ERGIC3 ERP29 EVI2B FAM209A FCER1G FFAR2 FKBP7 GJA8 GJB5 GPR152 GPR42 GPX8 IL10RA KIR2DL3 LMNA LY6G6C LYVE1 MMGT1 MUC1 ODF4 OPRM1 PANX1 PDCD1LG2 RNF5 SAR1A SCN3B SERP2 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC35H1 SPINT1 SSMEM1 SYPL2 TMEM237 TMEM52B TSPAN8 YIPF6	6 interacting genes: MEP1B PNLIPRP1 PTCH1 SLC38A7 STX2 TIMM23
Entrez ID		55238	7103
HPRD ID		07701	02865
Ensembl ID		ENSG00000103042	ENSG00000127324
Uniprot IDs		H3BMC5 Q9NVC3	P19075
PDB IDs
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Plasma Membrane Protein Binding Organic Hydroxy Compound Transport Water Transport Fluid Transport Channel Activity Water Channel Activity Gap Junction Channel Activity Monoatomic Ion Transport Positive Regulation Of Acute Inflammatory Response Gap Junction Bile Acid:sodium Symporter Activity Endoplasmic Reticulum Basolateral Plasma Membrane Organic Anion Transport Endoplasmic Reticulum Membrane Monoatomic Cation Transport Glycerol Transmembrane Transport Renal Water Transport Monoatomic Anion Channel Activity Polyol Transmembrane Transport Carbohydrate Transmembrane Transport Regulation Of Acute Inflammatory Response Inorganic Ion Transmembrane Transport Carbohydrate Transport Amine Transport Transport Vesicle Membrane Serotonin Transport Metal Ion Transport Monoatomic Ion Transmembrane Transport Monoatomic Anion Transmembrane Transport Inorganic Cation Transmembrane Transport	Meprin A Complex Response To Chlorate Neural Plate Axis Specification Hedgehog Family Protein Binding Hedgehog Receptor Activity L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity Asparagine Transport L-asparagine Transmembrane Transporter Activity
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