SLC38A7 and LYVE1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		SLC38A7	LYVE1
Description		solute carrier family 38 member 7	lymphatic vessel endothelial hyaluronan receptor 1
Image		No pdb structure
GO Annotations	Cellular Component	Lysosome Lysosomal Membrane Membrane Axon Cell Projection Neuronal Cell Body	Plasma Membrane Membrane Extracellular Exosome Cell Periphery
	Molecular Function	Protein Binding L-asparagine Transmembrane Transporter Activity L-glutamine Transmembrane Transporter Activity L-asparagine:sodium Symporter Activity L-glutamine:sodium Symporter Activity	Transmembrane Signaling Receptor Activity Protein Binding Hyaluronic Acid Binding Signaling Receptor Activity Cargo Receptor Activity
	Biological Process	Amino Acid Transmembrane Transport Monoatomic Ion Transport Sodium Ion Transport Amino Acid Transport Asparagine Transport Glutamine Transport	Positive Regulation Of Cellular Extravasation Glycosaminoglycan Catabolic Process Receptor-mediated Endocytosis Cell Adhesion Cell-matrix Adhesion Response To Wounding Anatomical Structure Morphogenesis Hyaluronan Catabolic Process
Pathways			Hyaluronan metabolism Hyaluronan degradation
Drugs			Hyaluronic acid
Diseases
GWAS		HDL cholesterol levels in HIV infection ( 33109212) Plasma anastrozole concentration in anastrozole-treated estrogen receptor positive breast cancer ( 30648747) QT interval ( 19305408) Schizophrenia ( 25056061 29483656) Suicide attempt severity in mood disorders ( 33783297)	Blood protein levels ( 30072576)
Interacting Genes		59 interacting genes: ACBD5 AMIGO1 APH1A AQP2 AQP6 AQP9 ARL13B BTNL9 CFTR CLCN7 CLDN7 CLEC10A CPLX4 CREB3L3 CYB561 CYB5R3 EDA ERGIC3 ERP29 EVI2B FAM209A FCER1G FFAR2 FKBP7 GJA8 GJB5 GPR152 GPR42 GPX8 IL10RA KIR2DL3 LMNA LY6G6C LYVE1 MMGT1 MUC1 ODF4 OPRM1 PANX1 PDCD1LG2 RNF5 SAR1A SCN3B SERP2 SHISAL1 SLC10A1 SLC10A6 SLC16A2 SLC18A1 SLC23A2 SLC30A2 SLC35H1 SPINT1 SSMEM1 SYPL2 TMEM237 TMEM52B TSPAN8 YIPF6	26 interacting genes: AIG1 AQP10 CLCN7 CYSRT1 EMP3 KRT34 KRTAP10-3 KRTAP10-8 KRTAP12-3 KRTAP6-2 KRTAP9-2 NBPF19 NINJ2 NOTCH2NLA NRSN1 PDGFB PIGF SERP2 SLC30A2 SLC38A7 SLC41A2 THSD7A THSD7B UBE2J1 VEGFA YIPF6
Entrez ID		55238	10894
HPRD ID		07701	05753
Ensembl ID		ENSG00000103042	ENSG00000133800
Uniprot IDs		H3BMC5 Q9NVC3	B2R672 Q9Y5Y7
PDB IDs			8OS2 8OXD
Enriched GO Terms of Interacting Partners?		Membrane Transmembrane Transport Plasma Membrane Protein Binding Organic Hydroxy Compound Transport Water Transport Fluid Transport Channel Activity Water Channel Activity Gap Junction Channel Activity Monoatomic Ion Transport Positive Regulation Of Acute Inflammatory Response Gap Junction Bile Acid:sodium Symporter Activity Endoplasmic Reticulum Basolateral Plasma Membrane Organic Anion Transport Endoplasmic Reticulum Membrane Monoatomic Cation Transport Glycerol Transmembrane Transport Renal Water Transport Monoatomic Anion Channel Activity Polyol Transmembrane Transport Carbohydrate Transmembrane Transport Regulation Of Acute Inflammatory Response Inorganic Ion Transmembrane Transport Carbohydrate Transport Amine Transport Transport Vesicle Membrane Serotonin Transport Metal Ion Transport Monoatomic Ion Transmembrane Transport Monoatomic Anion Transmembrane Transport Inorganic Cation Transmembrane Transport	Intermediate Filament Keratin Filament Positive Regulation Of Protein Autophosphorylation Regulation Of Protein Autophosphorylation Platelet-derived Growth Factor Receptor Binding Monoatomic Cation Transmembrane Transporter Activity
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